Patents Represented by Attorney, Agent or Law Firm Irving M. Fishman
  • Controlled release drug delivery device
    Patent number: 5681584
    Abstract: A drug delivery device for delivering a drug either intermittently or to a pre-selected region of the gastro-intestinal tract, particularly to the colon, consists of an a solid core comprising an active agent coated with a delay jacket, then coated with a semi-permeable membrane which is optionally drilled to provide a release orifice, and then optionally further coated with an enteric material. The device delivers substantially all of the active agent to the targeted site.
    Type: Grant
    Filed: March 22, 1996
    Date of Patent: October 28, 1997
    Assignee: Ciba-Geigy Corporation
    Inventors: Louis Savastano, James Carr, Elizabeth Quadros, Shailesh Shah, Satish Chaudra Khanna
  • Method of using abrasive blast media containing corrosion inhibitor
    Patent number: 5681205
    Abstract: A blast media is provided for cleaning a metal surface by wet blasting and which comprises a particulate abrasive such as sodium bicarbonate and a corrosion inhibitor comprising an alkali metal phosphate. The corrosion inhibitor has been found to greatly reduce the discoloration of metals which have been wet blasted with alkaline salt abrasives.
    Type: Grant
    Filed: April 21, 1995
    Date of Patent: October 28, 1997
    Assignee: Church & Dwight Co., Inc.
    Inventor: Benny S. Yam
  • Stable sodium percarbonate formulation
    Patent number: 5676933
    Abstract: This invention provides a stable hydrogen peroxide-releasing formulation in liquid or gel form, having a content of sodium percarbonate which is stabilized by a specific proportion of deionized water. The formulation ingredients can be incorporated in detergent or dentifrice compositions, and the sodium percarbonate ingredient exhibits long term stability during manufacture and storage of the compositions.
    Type: Grant
    Filed: July 13, 1995
    Date of Patent: October 14, 1997
    Assignee: Church & Dwight Co., Inc.
    Inventor: John P. Hauschild
  • Abrasive blast media containing corrosion inhibitor
    Patent number: 5669945
    Abstract: A blast media is provided for cleaning a metal surface by wet blasting and which comprises a particulate abrasive such as sodium bicarbonate and a corrosion inhibitor comprising an alkali metal phosphate. The corrosion inhibitor has been found to greatly reduce the discoloration of metals which have been wet blasted with alkaline salt abrasives.
    Type: Grant
    Filed: September 30, 1996
    Date of Patent: September 23, 1997
    Assignee: Church & Dwight Co., Inc.
    Inventor: Benny S. Yam
  • Use of compositions for combating tumour diseases
    Patent number: 5663168
    Abstract: The present invention relates to the use of inhibitors of HIV aspartate proteases, such as HIV-1- or HIV-2-protease, and their salts and to prodrugs for inhibiting the growth of tumors, especially those tumors which do not respond to the inhibition of HIV aspartate proteases themselves, and in the preparation of pharmaceutical compositions intended for use in the prophylaxis and especially the treatment of tumor diseases, and to methods and pharmaceutical compositions for the treatment of tumors with those compounds.
    Type: Grant
    Filed: May 16, 1994
    Date of Patent: September 2, 1997
    Assignee: CIBA-Geigy Corporation
    Inventors: Johannes Rosel, Urs Regenass, Marc Lang, Guido Bold, Frederic Cumin
  • Bicarbonate salt-containing deodorant cosmetic stick product
    Patent number: 5650141
    Abstract: This invention provides a deodorant cosmetic stick product which has a translucent or transparent light transmitting appearance. The cosmetic stick has a content of ingredients such as sodium bicarbonate, propylene glycol, sodium stearate, Steareth-100, Pentadoxynol-200, and water. An invention deodorant cosmetic stick has excellent esthetics when applied underarm, such as smoothness and a comfortable dry feel, and without a visually perceptible residue.
    Type: Grant
    Filed: September 13, 1995
    Date of Patent: July 22, 1997
    Assignee: Church & Dwight Co., Inc.
    Inventors: Wolfgang R. Bergmann, Richard T. Murphy, Linda J. Lancaster
  • Deodorant cosmetic stick composition
    Patent number: 5650143
    Abstract: This invention provides a deodorant cosmetic stick product which has a translucent or transparent light transmitting appearance. The cosmetic stick has a content of ingredients such as propylene glycol, sodium stearate, dimethicone copolyol, Triclosan, Pentadoxynol-200, and water. An invention deodorant cosmetic stick has excellent esthetics when applied underarm, such as smoothness and a comfortable dry feel, and without a visually perceptible residue.
    Type: Grant
    Filed: May 30, 1996
    Date of Patent: July 22, 1997
    Assignee: Church & Dwight Co., Inc.
    Inventors: Wolfgang R. Bergmann, Richard T. Murphy, Linda J. Lancaster
  • Deodorant cosmetic stick product
    Patent number: 5650140
    Abstract: This invention provides a deodorant cosmetic stick product which has a translucent or transparent light transmitting appearance. The cosmetic stick has a content of ingredients such as sodium bicarbonate, propylene glycol, sodium stearate, dimethicone copolyol, Pentadoxynol-200, and water. An invention deodorant cosmetic stick has excellent esthetics when applied underarm, such as smoothness and a comfortable dry feel, and without a visually perceptible residue.
    Type: Grant
    Filed: July 19, 1995
    Date of Patent: July 22, 1997
    Assignee: Church & Dwight Co., Inc.
    Inventors: Wolfgang R. Bergmann, Richard T. Murphy, Linda J. Lancaster
  • Bicarbonate-containing deodorant cosmetic stick compositions
    Patent number: 5650142
    Abstract: This invention provides a deodorant cosmetic stick product which has a translucent or transparent light transmitting appearance. The cosmetic stick has a content of ingredients such as sodium bicarbonate, propylene glycol, sodium stearate, Poloxomer 407, Pentadoxynol-200, and water. An invention deodorant cosmetic stick has excellent esthetics when applied underarm, such as smoothness and a comfortable dry feel, and without a visually perceptible residue.
    Type: Grant
    Filed: September 27, 1995
    Date of Patent: July 22, 1997
    Assignee: Church & Dwight Co., Inc.
    Inventors: Wolfgang R. Bergmann, Richard T. Murphy, Linda J. Lancaster
  • Aqueous metal cleaner
    Patent number: 5650385
    Abstract: A metal cleaning composition useful in aqueous solution comprises an alkalinity providing agent and a combination of surfactants comprising an ethoxylated thiol surfactant and a nitrogen-containing surfactant which reduces the odor of the thiol-containing surfactant. The aqueous cleaning solutions of this invention are particularly useful in metal parts washers typically placed in garages, service stations and the like in which the cleaning solution can be filtered and reused in the parts washer.
    Type: Grant
    Filed: March 4, 1996
    Date of Patent: July 22, 1997
    Assignee: Church & Dwight Co., Inc.
    Inventors: Steven Dunn, Anthony Winston
  • Production of enantiomerically enriched ortho-substituted .alpha.,.alpha.-diaromatic methanols
    Patent number: 5646330
    Abstract: A method of producing compounds of formula I ##STR1## wherein one of R.sub.1 and R.sub.2 is selected from --OH, --SH, and --NHR.sub.7 ; and the other of R.sub.1 and R.sub.2 is selected from H, --OH, --SH, --NHR.sub.7, and R.sub.8 ; R.sub.3 and R.sub.4 are each independently selected from R.sub.8 ; n and m are each independently 3; and each R.sub.5 and each R.sub.6 is independently selected from --OH, --SH, --NHR.sub.7, and R.sub.8 ; and R.sub.8 is as detailed in the specification;in enantiomerically enriched form, comprising reducing a compound of formula II ##STR2## wherein R.sub.1 -R.sub.6 are defined as in formula I, in the presence of B-haloisopinocampheylborane.
    Type: Grant
    Filed: February 17, 1995
    Date of Patent: July 8, 1997
    Assignee: Ciba-Geigy Corporation
    Inventors: Wen-Chung Shieh, William R. Cantrell, John Alan Carlson
  • Ultrafine sodium bicarbonate powder
    Patent number: 5645840
    Abstract: This invention provides alkali metal bicarbonate powder consisting of a narrow size distribution range of ultrafine particles. The ultrafine powder has a large surface area, and provides enhanced reactivity in applications such as deodorization or neutralization, and exhibits increased antibacterial/antifungal activity. The ultrafine powder also has an exceptional capability to form a homogenous solid-phase suspension in a liquid medium which has long term stability.
    Type: Grant
    Filed: October 12, 1995
    Date of Patent: July 8, 1997
    Assignee: Church & Dwight Co., Inc.
    Inventors: M. Stephen Lajoie, Anthony E. Winston
  • 5-amino-4-hydroxyhexanoic acid derivatives
    Patent number: 5643878
    Abstract: Compounds of formula I ##STR1## or their hydroxy-protected derivatives, and compounds of formula I' ##STR2## wherein T is an acyl radical of formula Z ##STR3## wherein R.sup.z is unsubstituted or substituted hydrocarbyl wherein at least one carbon atom has been replaced by a hetero atom with the proviso that a hetero atom is not bonded directly to the carbonyl to which the radical R.sup.z is bonded, alkyl having two or more carbon atoms, lower alkenyl, lower alkynyl, aryl or unsubstituted or substituted amino, and wherein the radicals R.sub.1, B.sub.1, R.sub.2, R.sub.3, A.sub.1, A.sub.2 and NR.sub.4 R.sub.5 are as defined in the description, and precursors thereof, are described. The compounds have pharmaceutical activity, for example in the treatment of retroviral diseases, such as AIDS.
    Type: Grant
    Filed: March 8, 1994
    Date of Patent: July 1, 1997
    Assignee: Ciba-Geigy Corporation
    Inventors: Guido Bold, Marc Lang, Alexander Fassler, Hans-Georg Capraro, Shripad Bhagwat, Peter Schneider, Peter van Hoogevest
  • Cosmetic deodorant products containing encapsulated co-micronized bicarbonate ingredient
    Patent number: 5631013
    Abstract: This invention provides cosmetic stick, roll-on and cream deodorant and deodorant-antiperspirant products. The cosmetic products consisting of an organic matrix having a dispersed phase of encapsulated particles of a co-micronized crystallite blend of inorganic compounds such as sodium bicarbonate and zinc oxide. The particle surfaces are coated with a polymer such as maltodextrin starch. When this type of cosmetic product is applied to underarm surfaces, a sustained deodorant activity by the encapsulated particles is obtained.
    Type: Grant
    Filed: August 7, 1995
    Date of Patent: May 20, 1997
    Assignee: Church & Dwight Co., Inc.
    Inventors: Wolfgang R. Bergmann, Richard T. Murphy
  • Anhydrous cosmetic product containing deodorant and desiccant ingredients
    Patent number: 5628990
    Abstract: This invention provides cosmetic deodorant stick, roll-on and cream formulations. An invention deodorant product comprises an organic matrix having a dispersed solids phase which includes discrete crystallites of bicarbonate salt ingredient and particulate boron oxide desiccant ingredient. When an invention deodorant product is applied to a skin surface, the boron oxide reacts with moisture, and converts to boric acid which neutralizes any content of a strong basic irritant such as alkali metal carbonate which is present as an impurity in an alkali metal bicarbonate salt.
    Type: Grant
    Filed: October 25, 1995
    Date of Patent: May 13, 1997
    Assignee: Church & Dwight Co., Inc.
    Inventors: Richard T. Murphy, Wolfgang R. Bergmann
  • Chewing gum product with dental care benefits
    Patent number: 5618517
    Abstract: The present invention provides a chewing gum product which has a content of one or more active ingredients for improved dental health. In one embodiment a present invention chewing gum product has a content of ingredients which include a gum base, dispersed particles of organic-encapsulated sodium bicarbonate, a bulking sweetener, and a flavorant.
    Type: Grant
    Filed: October 3, 1995
    Date of Patent: April 8, 1997
    Assignee: Church & Dwight Co., Inc.
    Inventor: Regina M. Miskewitz
  • Cosmetic deodorant products containing a polymer/fragrance-encapsulated bicarbonate ingredient
    Patent number: 5614179
    Abstract: This invention provides deodorant and antiperspirant-deodorant cosmetic stick and roll-on products with an organic matrix having a dispersed particle phase of an encapsulated bicarbonate salt ingredient such as sodium bicarbonate. The particle surfaces are coated with a film-forming medium comprising a blend of a polymer and a fragrance ingredient. When this type of cosmetic product is applied to underarm surfaces, the deodorizing activity is signaled by the release of a fragrance aroma.
    Type: Grant
    Filed: September 27, 1995
    Date of Patent: March 25, 1997
    Assignee: Church & Dwight Co., Inc.
    Inventors: Richard T. Murphy, Wolfgang R. Bergmann
  • Metal cleaner with novel anti-corrosion system
    Patent number: 5614027
    Abstract: A metal cleaning composition useful in aqueous solution comprises an alkalinity providing agent and a corrosion inhibitor comprising magnesium ions, zinc ions or both. The corrosion inhibitor is provided in the form of magnesium or zinc compounds such as magnesium oxide or water soluble salts thereof.
    Type: Grant
    Filed: September 23, 1994
    Date of Patent: March 25, 1997
    Assignee: Church & Dwight Co., Inc.
    Inventors: Steven Dunn, Anthony Winston
  • Pharmaceutical compositions comprising hybrid .alpha.-interferon
    Patent number: 5609868
    Abstract: The present invention provides a stable aqueous solution of hybrid .alpha.-Interferon which contains as the stabilizer a buffer at a pH of from 3.0 to 5.0.
    Type: Grant
    Filed: August 10, 1994
    Date of Patent: March 11, 1997
    Assignee: Ciba-Geigy Corporation
    Inventors: Nicholas Lowther, John D. Allen, Colin Howes
  • Blast media with defoamers
    Patent number: 5605491
    Abstract: A blast media for use in wet blasting to clean contaminants from a substrate surface comprises abrasive particles, at least one surfactant and a defoaming agent so as to reduce the amount of foam which is produced during the wet blasting process.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: February 25, 1997
    Assignee: Church & Dwight Co., Inc.
    Inventors: Benny S. Yam, Andrew Logan