Patents Represented by Attorney, Agent or Law Firm Isabella A. S. Blundell
  • Water insoluble derivatives of polyanionic polysaccharides
    Patent number: 6610669
    Abstract: A water insoluble, biocompatible gel is prepared by reacting carboxymethylcellulose and a carbodiimide, wherein the reaction is conducted in an aqueous medium containing a water miscible organic solvent, such as a lower alkanol, an alkyl pyrrolidone, DMSO or acetone. The present method permits the reaction to contain higher concentrations of carboxymethycellylose and less carbodiimide than conventional methods.
    Type: Grant
    Filed: December 22, 1999
    Date of Patent: August 26, 2003
    Assignee: Genzyme Corporation
    Inventors: Pericles Calias, Robert J. Miller