Abstract: A method and kit for predicting increased risk of sight-threatening diabetic retinopathy which includes isolating genomic DNA from a sample from a diabetic patient. The genetic polymorphism pattern for the genes IL-1A, IL-1B and IL-1RN is then identified in the DNA. The identified pattern is compared with control patterns of known polymorphisms, and patients expressing a genetic polymorphism pattern associated with increased risk of sight-threatening diabetic retinopathy are identified.
Type:
Grant
Filed:
March 10, 1998
Date of Patent:
March 30, 2004
Assignee:
Interleukin Genetics, Inc.
Inventors:
Gordon W. Duff, Patrick R. S. Richardson, Ian G. Rennie