Patents Represented by Attorney, Agent or Law Firm Ivor Elrifi
  • Contour measuring device and method
    Patent number: 6550151
    Abstract: The disclosed invention is an improvement on the traditional measuring wheel. When the odometry information is combined with two robust attitude sensors and an on-board computer, the instrument is able to perform useful measurements such as the calculation of an area or the description of a non-linear contour, as well as the traditional distance measurements and other uses.
    Type: Grant
    Filed: January 19, 2001
    Date of Patent: April 22, 2003
    Inventors: Donald R. Airey, Herman Servatius
  • Apparatus for deposition of ultrasound energy in body tissue
    Patent number: 6135971
    Abstract: An apparatus for providing ultrasonic energy for deposition in body tissue including an array of elements having at least two different sizes and at least one element being aperiodically spaced with the respect to other elements in the array. Excitation of the elements produces a beam of ultrasonic energy having reduced grating lobes. Reduced grating lobe magnitude permits improved ultrasonic beam focusing and/or the use of larger element sizes.
    Type: Grant
    Filed: November 8, 1996
    Date of Patent: October 24, 2000
    Assignee: Brigham and Women's Hospital
    Inventors: Erin Hutchinson, Mark Buchanan, Kullervo Hynynen
  • Methods for making immunoisolatory implantable vehicles with a biocompatiable jacket and a biocompatible matrix core
    Patent number: 5834001
    Abstract: A method of forming an implantable and retrievable immunoisolatory vehicle is disclosed, the method comprising the steps of first forming a jacket of biocompatible thermoplastic or hydrogel, and then loading the jacket with a core comprising a volume of at least 1 .mu.l and at least 10.sup.4 cells capable of secreting a biocompatible matrix comprising a hydrogel or extracellular matrix, said jacket having a molecular weight cutoff permitting passage of molecules thereacross to provide said biologically active product or said function.
    Type: Grant
    Filed: May 24, 1995
    Date of Patent: November 10, 1998
    Assignee: Brown University Research Foundation
    Inventors: Keith E. Dionne, Dwaine F. Emerich, Diane Hoffman, Paul R. Sanberg, Lisa Christenson, Orion D. Hegre, David W. Sharp, Paul E. Lacy, Patrick Aebischer, Alfred V. Vasconcellos, Michael J. Lysaght, Frank T. Gentile
  • Apparatus for forming hollow fibers and said fibers
    Patent number: 5656372
    Abstract: A nozzle assembly for forming hollow fibers, particularly a "Z-fiber" having longitudinally oriented trabeculae with the fiber wall, is disclosed. The nozzle assembly contains a replaceable nozzle cap, a replaceable seal-guide, and a retractable central bore used to supply core material for the hollow fibers. The Z-fibers are particularly useful in enabling cells, solutes, or the like, to enter the fiber wall and move longitudinally into the center of the fiber wall.
    Type: Grant
    Filed: June 1, 1995
    Date of Patent: August 12, 1997
    Assignee: Brown University Research Foundation, Inc.
    Inventors: Frank T. Gentile, Michael J. Lysaght, Nicholas F. Warner
  • Microdrive for use in stereotactic surgery
    Patent number: 5643286
    Abstract: The present invention is directed to microdrive apparatus useful in human stereotactic surgery. Such apparatus permits safe and accurate placement of a surgical instrument, such as a cannula, into a portion of the central nervous system, e.g. the brain and spinal cord, of a patient by simple mechanical operation.
    Type: Grant
    Filed: June 24, 1994
    Date of Patent: July 1, 1997
    Assignee: CytoTherapeutics, Inc.
    Inventors: Nicholas Warner, Moses Goddard, John Mills