Abstract: Methods, assays and kits are disclosed for detecting a mother's or a fetus's susceptibility to an adverse pregnancy outcome such as low birth weight. The methods comprise obtaining a biological sample from a patient and determining the presence or absence of an IL-1 allele 2 of a marker that is associated with an adverse pregnancy outcome.
Type:
Grant
Filed:
October 20, 2000
Date of Patent:
May 11, 2004
Assignees:
Interleukin Genetics, Inc., The University of North Carolina at Chapel Hill
Inventors:
Kenneth S. Kornman, Gordon W. Duff, Steven Offenbacher