Abstract: Toothpaste compositions containing pyrophosphate or phosphonic acid salt and 3 pyridylmethanol, which compositions are effective against calculus.

Abstract: Oral compositions containing a cationic antimicrobial agent and benzoic acid and phthalic acid or salts of these acids, which compositions are effective against plaque and gingivitis, are disclosed. Also disclosed are methods for reducing plaque and gingivitis.

Abstract: Disclosed are oral compositions containing phosphocitrate to provide improved anticalculus activity.

Abstract: Anhydrous oral compositions are disclosed containing an anhydrous humectant and a carboxyvinyl polymer neutralized with an appropriate base.

Abstract: The present invention involves process for the preparation of compounds having the chemical structure: ##STR1## wherein Ar--H is an aromatic compound which is activated to an electrophilic attack, and wherein --Y is an aliphatic group having a labile moiety, especially where the labile moiety is a terminally unsaturated moiety: --C.tbd.CH, ##STR2## or aldehydes in the form of their acetals. The process comprises the step of reacting Ar--H and ##STR3## wherein --X is --Cl or --Br, and where the reaction step is carried out in a solvent medium at a temperature of from about -40.degree. C. to about -100.degree. C. using stannic chloride as a catalyst.

Abstract: Oral compositions effective against caries containing strontium EDTA and a soluble fluoride ion source are described herein.

Abstract: Skin conditioning/cleansing compositions containing specific propoxylated glycerol derivatives are disclosed. These compositions possess both excellent skin conditioning and aesthetic properties.

Abstract: This disclosure relates to drug-polymer matrix compositions comprising an active ingredient having an amine or amido group and a pharmaceutically acceptable copolymer having a plurality of carboxylic acid and ester groups wherein the matrix dissociates in a media having a pH of less than 4, thereby releasing the active ingredient into the media.

Abstract: The present invention involves processes for making aminomethylene phosphonoalkylphosphinate compounds comprising:(a) heating a substantially anhydrous mixture comprising an amine, an ester of an alkyl phosphite, and an ester of a phosphate acetal; and then(b) adding water to the mixture.

Abstract: An oil-in-water-in-silicone fluid (o/w/s) emulsion composition comprising (a) a silicone fluid continuous phase, (b) an aqueous discontinuous phase comprising an oil-in-water (o/w) emulsion, and (c) an effective dispersing amount of dimethicone copolyol for dispersing (b) in (a).

Abstract: The invention involves methods for the treatment and prophylaxis of human or animal subjects having infectious gastrointestinal disorders of the upper gastrointestinal tract caused or mediated by Campylobacter-like organisms comprising the step of administering to the subjects safe and effective amounts of nitrofurantoin.

Abstract: Oral compositions such as toothpastes, mouthwashes, lozenges and chewing gum containing an antimicrobial agent which is effective against plaque/gingivitis and mouth odor ar disclosed.

Abstract: Novel cyclic geminal-diphosphonic acid compounds, and pharmaceutical compositions containing these compounds, which are useful for treating diseases characterized by abnormal calcium and phosphate metabolism; and a method of treating diseases characterized by abnormal calcium and phosphate metabolism utilizing these novel cyclic diphosphonic acid compounds.

Abstract: The present invention relates to novel chromophore-containing compounds useful as sunscreen agents which have the ability to absorb both UVA and UVB wavelength radiation. These compounds comprise a specific type of UVA-absorbing chromophore covalently bonded to a specific type of UVB-absorbing chromophore. The chromophore moieties are covalently bonded together such that the electron systems of these moieties are directly coupled to thereby form a new chromophore.The present invention further relates to sunscreen compositions containing the hereinbefore described type of sunscreen agents. Furthermore, the present invention relates to methods for protecting the skin or humans or lower animals from the effects of UVA and UVB wavelength radiation. This method comprises topically applying to the skin an effective coating of a sunscreen composition of the present invention.

Abstract: Disclosed are oral anesthetic pharmaceutical compositions comprising: (a) from about 0.02% to about 25% of a pharmaceutically acceptable acid salt of a .beta.-aminopropiophenone, such as dyclonine HCl; (b) from about 0.02% to about 20% of saccharin; and (c) from about 1% to about 99% of a pharmaceutically acceptable oral carrier. Also provided are methods for providing an anesthetic effect in humans or animals which comprises orally administering to said human or animal a safe and effective amount of these pharmaceutically compositions. Also provided is a novel process for the manufacture of anesthetic lozenges containing a .beta.-aminopropiophenone along with saccharin.

Abstract: Novel pharmaceutical compositions of matter are disclosed for use in eliciting a topical anesthetic and antimicrobial response, preferably for oral health care purposes, said compositions comprising dyclonine hydrochloride and phenol. When used in combination, dyclonine hydrochloride and phenol provide an improved antimicrobial response.

Abstract: Disclosed are wax based cosmetic stick compositions comprising: from about 10% to about 50% of a wax type solidifying agent; and from about 5% to about 90% of a polyalphaolefin. These compositions preferably comprise from about 1.0% to about 40% of an active component, such as a sunscreen agent, analgesic, moisturizing and antiperspirant or a deodorant active.

Abstract: Compounds and diastereomeric mixtures of specific 2-naphthyl-containing ester compounds, especially naproxen ester and naproxol ester compounds, having two or more chiral centers. These compounds are effective as anti-inflammatory agents, analgesic agents, and/or antipyretic agents. They are readily absorbed as the diastereomeric mixture, especially through the skin following topical application.

Abstract: Methods for reducing calculus are disclosed utilizing oral compositions containing stannous ions complexed with certain carboxylic acids or polyhydric alcohols.

Abstract: Methods of treating non-inflammatory diseases characterized by abnormal calcium and phosphate metabolism comprising administering a pharmaceutical composition comprising a geminal diphosphonic acid compound in which the diphosphonic acid-containing carbon is linker via a sulfur atom or a sulfur-containing chain to a 6-membered aromatic ring containing one or more nitrogen atoms.