Abstract: The present invention relates to a new pharmaceutical composition with synergistic properties, to dosage units thereof, and to the use of the said composition and dosage units in the human or veterinary practice for the treatment of patients suffering from infectious diseases. The composition contains as active ingredients an amidinopenicillanic acid derivative of the formula ##STR1## in which R is hydrogen or a lower alkanoyloxymethyl radical including the pivaloyloxymethyl radical or atoxic salts thereof in combination with 2,4-diamino-5(3,4,5-trimethoxybenzyl)-pyrimidine, also known under the name trimethoprim, used hereinafter, or atoxic salts thereof.

Abstract: This involves an in vitro assay system to screen for mutagenic and/or carcinogenic agents based on alterations in the fidelity of DNA synthesis. In the system, chemicals will be tested for their mutagenicity or carcinogenicity by measuring increases in the number of mistakes incorporated by purified DNA polymerases using synthetic polynucleotide templates. This system offers the advantage of performing this analysis in the test tube so that all parameters in the reaction can be monitored. Agents that enhance misincorporation during DNA synthesis would be predicted to have a higher probability of being mutagens or carcinogens in the human population.

Abstract: This is a process and product in which excellent properties are achieved with a relatively low alloy steel and normal rolling with a steel having the following composition in addition to iron and impurities, in percentages by weight:______________________________________ Carbon .05 to .12 Manganese .25 to .90 Silicon .15 to .50 Nickel .15 to .50 Copper .15 to .50 Aluminum .02 to .110 Niobium (Columbium) .07 to .140 Nitrogen .007 to .015 Phosphorus .010 maximum Sulfur .025 maximum.

Abstract: A wire connector having an insulating body of S-shaped cross section wherein the bends of the S form wire-receiving channels. A pair of hinged and latched covers keep the wires in the channels. A metal contact plate is supported in the body and electrically connects the wires.

Abstract: Nasal protection for the nostrils comprising a U-shaped wire-spring having an ellipsoidal-like nub fastened to each end for pressing the nostrils.

Abstract: A cape especially valuable for dealing with the hair made preferably of turkish toweling or in a particular case plastic, but suitably of various other materials, consisting of a shoulder-embracing portion, a slot for the head, two tongues surrounding the neck, there being curving lobes at the base of the tongues for overlapping on the chest or behind the shoulders. Special surface-type fasteners sit on the tongues near the end, and cooperating contact surface-type fastening places are near the top of the lobes. There are preferably also loops near the tops of the lobes which can surround the other tongues.

Abstract: A treatment for hypertension by the conjoint use of phenoxybenzamine and propranolol, desirably with the conjoint use also of a diuretic.

Abstract: In flux-cored wire electrodes for vertical automatic welding, from bottom to top, there is an electric arc under gaseous protection, the wires having diameters of 1 to 4 mm and generally shaped internally in any configuration, such as tubular, heart-shaped and composite, characterized by a sheath of steel strip, and a powdered filling flux most preferably including the following ingredients in qualitative and quantitative composition by powder weight:______________________________________ Iron powder 73% Silicofluoride of potassium (K.sub.2 SiF.sub.6) 4% Cryolite (Na.sub.3 AlF.sub.6) 2% Nickel powder 3% Ferro-molybdenum (at 65 up to 75%) 0.8% Refined ferromanganese (85 up to 90%) 9.9% Ferrosilicon (45%) 1% Ferrotitanium (30%) 0.5% Micaceous iron oxide 1% Fine silica 4% Silicocalcium (SiCa) 0.8% 100.0% ______________________________________The flux-cored wires most preferably have a filling coefficient of 32 grams of powder weight per 100 grams of strip.

Abstract: Compounds of the general formulae ##STR1## in which R.sub.1 represents a straight or branched, optionally substituted alkyl, alkenyl or alkynyl radical; R.sub.2 stands for an optionally substituted phenyl radical; Y stands for oxygen, sulphur or a methylene radical; X stands for O or H.sub.2 ; their salts and esters and methods for their preparation.The compounds of the invention possess an outstanding diuretic and saluretic activity with a very low excretion of potassium ions and a low toxicity.

Abstract: Flux-cored wire for automatic or semi-automatic arc welding process, comporting specific powder compositions as detailed in the description, which are high in amounts of metallic powders, mixed with metallic silicate solution to form a paste and baked before its introduction within a low-carbon or low-alloy steel sheath.

Abstract: The invention relates to single, paired opposite phased and multiple stacked insulated flexible or rigid bus bar electrical conductors of copper or aluminum assembled side by side (optionally in a factory or at installation site) as high current density circuits into open trays of substantial length and covers to totally enclose a heat transfer tray co-extensive with the tray and having clamps extending across the tray to secure the cover to the tray and urging the cover upon conductors or conductor joints in the tray by tightening single bolts per clamp. Also, the invention involves making externally operable end to end overlap compression circuit joints of bus bar conductors simultaneously with one or more single bolt clamps for each single, paired phase and multiple stack, electrically insulated apart and supported within the metal tray.

Abstract: A writing device including a barrel containing a battery powered motor having a shaft extending through one end of the barrel, preferably interchangeable writing tips and a connection to the shaft by a very flexible connector. The device enables production of impressions and designs on a writing surface whose character is dependent upon the flexible connection, the tip and the writing surface, and whose variety is limited only by the will of the operator. The device is useful for example as a toy or an artist's tool.

Abstract: Our invention relates to the feeding of sodium to aluminum containing silicon as an alloying element in hypoeutectic percentages by flowing the molten aluminum through a trough and feeding a tube which contains sodium within it into the aluminum in the trough, the tube being preferably fed in countercurrent direction with special mixing and a protective surface coating for the flowing molten aluminum. The invention appears primarily applicable to casting large masses of aluminum such as are used in the melts which produce aluminum ingots for sale to foundries.

Abstract: The present invention relates to a series of new compounds, their salts and esters and to methods for the preparation of the compounds having the general formula: ##SPC1##In which R.sub.1 represents a straight or branched C.sub.1 -C.sub.6 alkyl, alkenyl or alkynyl radical, or a C.sub.1 -C.sub.3 alkyl radical substituted with phenyl, halophenyl, trifluoromethylphenyl, (lower alkoxy)phenyl, or with a 5-membered or 6-membered heterocyclic ring containing not more than two heteroatoms selected from the group consisting of oxygen, sulphur and nitrogen; R.sub.2 stands for hydrogen or a straight or branched C.sub.1 -C.sub.6 alkyl, alkenyl, alkynyl or alkoxy radical, optionally being substituted with halogen, a lower alkoxy or di-(lower alkyl) amino radical; Ar stands for a phenyl radical, optionally being substituted with halogen, lower alkyl, or lower alkoxy; Y stands for oxygen, sulphur or a methylene radical.

Abstract: Compounds of the general formula ##SPC1##In which R.sub.1 represents a straight or branched C.sub.1 -C.sub.6 alkyl, alkenyl or alkynyl radical, or a C.sub.1 -C.sub.3 alkyl radical substituted with phenyl, halophenyl, trifluoromethylphenyl, (lower alkoxy)phenyl, or with a 5-membered or 6-membered heterocyclic ring containing not more than two heteroatoms selected from the group consisting of oxygen, sulphur and nitrogen; R.sub.2 stands for a phenyl radical, optionally being substituted with halogen, lower alkyl, hydroxy, or lower alkoxy; X and Y stand for oxygen or sulphur; their salts and esters and methods for their preparation. The compounds of the invention possess an outstanding diuretic and saluretic activity with a very low excretion of potassium ions and a low toxicity.

Abstract: The invention comprises an improved electrolytic cell of the Keidel type, U.S. Pat. No. 2,830,945, in which the original set of electrodes is replaced by two sets having a ratio of length of not less than 3 to 1 and having independent terminals and independent bodies coupled together. The invention also may comprise potting the element including the longer set of electrodes and leaving the element including the shorter set of electrodes unpotted.

Abstract: The invention relates to hitherto unknown derivatives of 6-aminopenicillanic acids of the formula ##SPC1##In which R.sub.1 and R.sub.2 are similar or different aliphatic, cycloaliphatic, aromatic or heterocyclic substituents linked directly or through alkyl groups to the nitrogen atom, or R.sub.1 and R.sub.2 together with the nitrogen atom form a heterocyclic ring, and R.sub.3 is a hydroxyl or substituted hydroxyl group; to pharmaceutically acceptable salts, and to methods for producing these new compounds having a strong antibacterial effect, especially on gram-negative bacteria, to pharmaceutical preparations in dosage unit forms containing the compounds of the invention solely, or in synergistic mixtures with penicillins, and to methods of treating patients with the dosage units.

Abstract: The present invention relates to pivaloyloxymethyl D(-)-.alpha.-aminobenzylpenicillinate of the formula I in a novel and improved form, i.e. the crystalline form ##SPC1##To methods of producing said crystalline pivaloyloxymethyl D(-)-.alpha.-aminobenzylpenicillinate and to pharmaceutical preparations containing said crystalline pivaloyloxymethyl D(-)-.alpha.-aminobenzylpenicillinate.Crystalline pivaloyloxymethyl D(-)-.alpha.-aminobenzylpenicillinate has no bitter taste, is only slightly soluble in water, and is stable and readily absorbable.

Abstract: The invention relates to a series of new compounds, to salts of these compounds and to methods for the preparation of the compounds. The new compounds have the general formula: ##EQU1## in which n is an integer from 0 to 5; and A is selected from the group consisting of an unsubstituted or substituted aliphatic, alicyclic, aromatic and heterocyclic radical.The compounds of the invention are broad-spectrum antibiotics especially usable for oral administration.

Abstract: The invention relates to a new lock for the inner race of a self-aligning bushing to a shaft.