Patents Represented by Attorney, Agent or Law Firm Jacqueline S. Larson
  • Patent number: 7784724
    Abstract: A fishing reel that employs a non-contact line sensor to capture images of the backlash zone of a baitcast fishing reel, together with image analysis and feedback to a direct contact spool brake, with the result of gradual to near-instantaneously halting spool rotation, thereby decreasing or preventing backlash under all fishing conditions while maximizing cast distance.
    Type: Grant
    Filed: October 11, 2008
    Date of Patent: August 31, 2010
    Inventor: James P. Beckham
  • Patent number: 7776896
    Abstract: This invention is directed to compounds of formula (I): where A, B, D, E, m, and R1-R5 are as described herein, as single stereoisomers or as mixtures of stereoisomers, or pharmaceutically acceptable salts, clathrates, or prodrugs thereof, which compounds are useful in treating respiratory diseases associated with influenza A viruses, such as for example H5N1 and its mutations. Pharmaceutical compositions comprising the compounds of the invention and methods of preparing the compounds of the invention are also disclosed.
    Type: Grant
    Filed: March 27, 2008
    Date of Patent: August 17, 2010
    Assignee: Bayer Schering Pharma Aktiengesellschaft
    Inventors: William Guilford, Werner Skuballa, Daryl H. Faulds, Monica Kochanny, Wheeseong Lee, Bernd Radüchel
  • Patent number: 7737145
    Abstract: This invention is directed to compounds of formula (I): where r, q, R, R2, R3, R4, R5a, R5b, R5c, R6a, R6b, R6c, R7, R8, and R9 are described herein, as single stereoisomers or as mixtures of stereoisomers, or pharmaceutically acceptable salts, solvates, clathrates, polymorphs, ammonium ions, N-oxides or prodrugs thereof; which are leukotriene A4 hydrolase inhibitors and therefore useful in treating inflammatory disorders. Pharmaceutical compositions comprising the compounds of the invention and methods of preparing the compounds of the invention are also disclosed.
    Type: Grant
    Filed: December 22, 2006
    Date of Patent: June 15, 2010
    Assignee: Estrellita Pharmaceuticals, LLC
    Inventors: Damian Arnaiz, Greg Brown, Emmanuel Claret, Arwed Cleve, David Davey, William Guilford, Seock-Kyu Khim, Thomas Kirkland, Monica J. Kochanny, Amy Liang, David Light, John Parkinson, David Vogel, Guo Ping Wei, Bin Ye
  • Patent number: 7662873
    Abstract: The present invention is directed to the preparation of fibrous substrates, including textiles, marked with colloidal particle nanobar codes, to the fibrous substrates so prepared, and to methods for detecting the nanobar codes on the fibrous substrates for use in quality control, counterfeiting, and the like.
    Type: Grant
    Filed: February 20, 2004
    Date of Patent: February 16, 2010
    Assignee: Nano-Tex, Inc.
    Inventors: David A. Offord, William Ware, Jr.
  • Patent number: 7434757
    Abstract: A fishing reel directly measuring line travel (not velocity or acceleration) past two or more points along the line, with said data being fed back in real time to a comparative control loop which initiates a direct contact spool brake to slow or near-instantaneously halt spool rotation in order to maximize casting distance while eliminating backlash under all casting conditions. During the cast, the line length fed from the spool is prevented from exceeding (to the point of backlash) the line length being pulled out from the spool. During a cast in which the lure is suddenly halted (as in the case of the lure striking a structure or object), the system senses control instability and fully halts the spool rotation so that backlash is prevented.
    Type: Grant
    Filed: July 25, 2007
    Date of Patent: October 14, 2008
    Inventor: James P. Beckham
  • Patent number: 7427300
    Abstract: This invention is directed to fabric finishes or treatment preparations for nylon, polyester, and other textile and fibrous substrate materials that will render them hydrophilic. The finishes of the invention are comprised primarily of polymers that contain carboxyl groups, salts of carboxyl groups, or moieties that can be converted to carboxyl groups by some chemical reaction.
    Type: Grant
    Filed: March 24, 2005
    Date of Patent: September 23, 2008
    Assignee: Nano-Tex, Inc.
    Inventors: David S. Soane, Dan B. Millward, Matthew R. Linford, Ryan Lau, Eric G. Green, William Ware, Jr.
  • Patent number: 7141566
    Abstract: The invention relates to compounds of formula (I), the tautomeric and isomeric forms and salts thereof, in addition to a method for production and use thereof in medicaments.
    Type: Grant
    Filed: August 23, 2000
    Date of Patent: November 28, 2006
    Assignee: Schering Aktiengesellschaft
    Inventors: Peter Hölscher, Hartmut Rehwinkel, Stefan Jaroch, Detlev Sülzle, Margrit Hillmann, Gerardine Anne Burton, Fiona Mcdougall McDonald
  • Patent number: 7084142
    Abstract: Compounds of the following formula: where m, n, R1, R2, R3, R4 and R6 are described herein, are useful as inhibitors of platelet adenosine diphosphate. Pharmaceutical compositions containing these compounds, methods of using these compounds as antithrombotic agents and processes for synthesizing these compounds are also described herein.
    Type: Grant
    Filed: January 12, 2006
    Date of Patent: August 1, 2006
    Assignee: Schering Aktiengesellschaft
    Inventors: Judi Bryant, Brad Buckman, Imadul Islam, Raju Mohan, Michael Morrissey, Guo Ping Wei, Wei Xu, Shendong Yuan
  • Patent number: 7053112
    Abstract: A compound is disclosed, which is useful in treating a mammal having a disease-state characterized by thrombotic activity. The compound is of the following formula: wherein A, B, R1, R2, R3 and R4 are as defined herein or an isomer or isomeric mixture thereof or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: September 23, 2003
    Date of Patent: May 30, 2006
    Assignee: Schering Aktiengesellschaft
    Inventors: Damian O. Arnaiz, Yuo-Ling Chou, Brian D. Griedel, Raju Mohan, Kenneth J. Shaw
  • Patent number: 6951712
    Abstract: The present invention is directed to a cryoprotective system that comprises an aqueous solution containing polymeric nano- and micro-particles that exhibit a reversible temperature-dependent volume change. It is also directed to a method for providing cryoprotection to an organism or parts of an organism by pumping the cryoprotective system into the vasculature of the organism prior to exposing the organism to a lower, preferably below 0° C., temperature.
    Type: Grant
    Filed: March 14, 2001
    Date of Patent: October 4, 2005
    Inventors: David S. Soane, Stephen E. Barry, Rachel Decor
  • Patent number: 6949262
    Abstract: A treatment composition for use in providing relief of dryness of the nasal tissues and other dry skin, and particularly to providing such relief without the use of petroleum products.
    Type: Grant
    Filed: May 27, 2003
    Date of Patent: September 27, 2005
    Assignee: LouSal Enterprises, Inc.
    Inventor: Don L. Smothers
  • Patent number: 6884842
    Abstract: Synthetic polymer complements (SPCs) are provided, as well as methods for their synthesis and use. The SPCs may have surfaces that include functional groups that are complementary to surface sites of targets such as nanostructures or macromolecular targets, and may be capable of specifically interacting with such targets. The positions of the functional groups in one embodiment are stabilized by a polymer network. The SPCs are formed by contacting the target with a set of monomers which self-assemble on the target, and then are polymerized into a network to form the synthetic polymer complement. At least a portion of the surface of the resulting SPC thus may include an imprint of the target. The complex of the SPC and the target may be the desired product. Alternatively, the target is released, for example, by controllably expanding and contracting the crosslinked network. The SPC is isolated and used in many applications.
    Type: Grant
    Filed: October 26, 2001
    Date of Patent: April 26, 2005
    Assignee: Alnis BioSciences, Inc.
    Inventors: David S. Soane, Stephen E. Barry, Andrew Goodwin, David A. Offord, Michael G. Perrott
  • Patent number: 6821458
    Abstract: This disclosure describes a processing approach for the rapid and efficient in-situ polymerization of specially prepared precursor mixtures to achieve near-net-shape production of objects/articles with exact dimensions. The process relies on the use of polymerizable compositions comprised of a mixture of a dead polymer, a reactive plasticizer and an initiator, which compositions are semi-solid-like prior to curing and induce low shrinkage upon curing as a result of their partially polymerized nature prior to processing. The partially polymerized nature of the precursor mixtures also allows extremely impact-resistant objects/articles to be fabricated. Other desirable engineering property attributes can similarly be achieved via the judicious blending of starting ingredients in formulating the polymerizable (curable) mixtures.
    Type: Grant
    Filed: December 5, 2001
    Date of Patent: November 23, 2004
    Assignee: ZMS, LLC
    Inventors: David S. Soane, Michael R. Houston, Toshiaki Hino
  • Patent number: 6821509
    Abstract: The present invention is directed to a hair treatment preparation comprising a payload in an intimate relationship to a polymeric nanostructure, the polymeric nanostructure being reactive to hair or capable of being immobilized onto or in hair. The nanoscopic nature of the entities being engineered ensures three distinct characteristics. First, the imparted attribute can be either nearly permanent or semi-permanent, depending on the attachment chemistry. In the semi-permanent version, the intended effect can be controllably erased by removal of the nanostructure by simple chemical or physical means. Second, the nanoscopic entities are invisibly small. Their presence does not deteriorate the hand or feel of the hair. Third, the nano-technology approach is infinitely flexible and adaptable. It can be coupled with many existing dyes, colorants, UV absorbers, fragrances, softening agents and the like for hair treatment.
    Type: Grant
    Filed: October 11, 2002
    Date of Patent: November 23, 2004
    Assignee: Cosmetica, Inc.
    Inventors: David S. Soane, Matthew R. Linford
  • Patent number: 6749779
    Abstract: This disclosure describes a processing approach for the rapid and efficient in-situ polymerization of specially prepared precursor mixtures to achieve near-net-shape production of objects/articles with exact dimensions. The process relies on the use of polymerizable compositions comprised of a mixture of a reactive plasticizer and an initiator, optionally also including a dead polymer, which compositions are semi-solid-like and induce little shrinkage upon curing as a result of their partially polymerized nature prior to processing. The articles of the invention have a surface and an interior core, the composition of the surface material being distinct from the composition of the core material while at the same time the surface and the core are an integral, monolithic entity. In addition, the articles are dimensionally stable and exhibit high fidelity replication.
    Type: Grant
    Filed: September 14, 2001
    Date of Patent: June 15, 2004
    Assignee: ZMS, LLC
    Inventors: David S. Soane, Michael R. Houston, Toshiaki Hino
  • Patent number: 6733700
    Abstract: This invention is directed to a process for the rapid in-situ curing of polymerizable materials to provide macro-molecular networks and articles of manufacture that are “morphology-trapped”; that is, they exhibit a fixed phase morphology and/or molecular orientation that is locked in by the curing step. The process includes the steps of mixing together a dead polymer or a prepolymer, a reactive plasticizer or a diulent, and an initiator to give a polymerizable composition; further processing the mixture in order to achieve a desired phase morphology and/or moelcular orientation of the polymeric constitutents; shaping the polymerizable composition into a desired geometry; and exposing the polymerizable composition to a source of polymerizing energy, without mixing to give a final product with the desired phase morphology and/or moelcular orientation locked in place.
    Type: Grant
    Filed: December 9, 2002
    Date of Patent: May 11, 2004
    Assignee: ZMS, LLC
    Inventors: Michael R. Houston, Toshiaki Hino, David S. Soane
  • Patent number: 6679924
    Abstract: This invention is directed to treatments for dyed textile goods that will improve their fastness properties. More particularly, the invention is directed to certain fixatives that, when placed on the dyed textile, allow the dye to be permanently or substantially permanently affixed to the fabric. The dye-reactive fixative comprises a water-soluble or water-dispersible polymer or oligomer having reactive groups that react with a dye on a dyed web to affix the dye to the web.
    Type: Grant
    Filed: January 31, 2003
    Date of Patent: January 20, 2004
    Assignee: Nano-Tex, LLC
    Inventors: William Ware, Jr., David S. Soane, Dan B. Millward, Matthew R. Linford
  • Patent number: 6638984
    Abstract: The present invention is directed to thermo-expandable microspheres and to the expanded microballoons, microcellular foam or foamed composite material that results upon heating the microspheres. The thermo-expandable microsphere of the present invention is characterized by having a polymeric wall surrounding one or more pockets or particles of blowing agent or propellant within the microsphere. The polymeric wall may have reactive functional groups on its surface to give a fusible microsphere. When the microspheres are heated, they expand to form microballoons comprising polymeric shells surrounding one or more internal gaseous voids, and when the microspheres are expanded while in contact with each other, a microcellular foam may be formed. The foam consists of a plurality of microballoons fused together, optionally aided by functional groups present on the surface of the heated microspheres that act to crosslink the material.
    Type: Grant
    Filed: September 5, 2002
    Date of Patent: October 28, 2003
    Assignee: Nano-Tex, LLC
    Inventors: David S. Soane, Michael R. Houston
  • Patent number: 6617364
    Abstract: The present invention is directed to thermo-expandable microspheres and to the expanded microballoons, microcellular foam or foamed composite material that results upon heating the microspheres. The thermo-expandable microsphere of the present invention is characterized by having a polymeric wall surrounding one or more pockets or particles of blowing agent or propellant within the microsphere. The polymeric wall may have reactive functional groups on its surface to give a fusible microsphere. When the microspheres are heated, they expand to form microballoons comprising polymeric shells surrounding one or more internal gaseous voids, and when the microspheres are expanded while in contact with each other, a microcellular foam may be formed. The foam consists of a plurality of microballoons fused together, optionally aided by functional groups present on the surface of the heated microspheres that act to crosslink the material.
    Type: Grant
    Filed: September 5, 2002
    Date of Patent: September 9, 2003
    Assignee: Nano-Tex, LLC
    Inventors: David S. Soane, Michael R. Houston
  • Patent number: 6617268
    Abstract: This invention is directed to methods for the treatment of cellulose-containing fibers and yarn to provide protection to the cellulose from attack by enzymes. The method comprises the steps of exposing cellulose-containing fibers and yarn to an aqueous solution of an enzyme-repelling chemical to give the fibers or yarn a protective coating, and using the protectively coated fibers and yarn to prepare cloth or fabric. In another embodiment, the method of the invention comprises the step of exposing a fabric comprising cellulose-containing yarn to an aqueous solution of an enzyme-repelling chemical to give the fabric a protective coating. The invention also encompasses cellulose-containing fibers and yarn, including cotton, having a protective enzyme-repelling coating. The invention is further directed to denim fabric comprising cotton fill yarn having a protective enzyme-repelling coating.
    Type: Grant
    Filed: June 26, 2000
    Date of Patent: September 9, 2003
    Assignee: Nano-Tex, LLC
    Inventors: David A. Offord, David S. Soane, William Ware, Jr., Matthew R. Linford