Patents Represented by Attorney, Agent or Law Firm James D. Darnley
  • Compositions and methods for treating bacterial infections
    Patent number: 6544991
    Abstract: A composition having antibacterial activity is disclosed. More particularly, a mixture of an oxazolidinone compound, sulbactam, and ampicillin active agents, demonstrating activity against resistant strains of bacteria is disclosed. Methods for using an oxazolidinone compound, sulbactam, and ampicillin to treat a bacterial infection are also described.
    Type: Grant
    Filed: June 21, 2001
    Date of Patent: April 8, 2003
    Assignee: Pharmacia & Upjohn Company
    Inventors: Donald H. Batts, Keiichi Hiramatsu
  • Pseudorabies virus protein
    Patent number: 6521231
    Abstract: The present invention provides recombinant DNA molecules comprising a sequence encoding a pseudorabies virus (PRV) glycoprotein selected from the group consisting of gI, gp50, and gp63, host cells transformed by said recombinant DNA molecule sequences, the gI, gp50 and gp63 polypeptides. The present invention also provides subunit vaccines for PRV, methods for protecting animals against PRV infection and methods for distinguishing between infected and vaccinated animals.
    Type: Grant
    Filed: October 20, 2000
    Date of Patent: February 18, 2003
    Assignee: Pharamcia & Upjohn Company
    Inventors: Erik Aivars Petrovskis, Leonard Edwin Post, James G. Timmins
  • Methanol derivatives for treatment of retroviral infections especially HIV infections
    Patent number: 6191124
    Abstract: The present invention relates to compounds of formula (I) which are imidazo[2,1-b]benzothiazole-3-methanol and imidazo[2,1-b]thiazole-5-methanol derivatives useful for inhibiting a retrovirus in a mammalian cell infected with said retrovirus, wherein R1 is —H or —CH3; wherein R2 is —H or —CH3; or wherein R1 and R2 taken together are (a) formula (II), or (b) formula (III).
    Type: Grant
    Filed: April 7, 1997
    Date of Patent: February 20, 2001
    Assignee: Pharmacia & Upjohn Company
    Inventor: Herman W. Smith
  • Pseudorabies virus protein
    Patent number: 6172186
    Abstract: The present invention provides recombinant DNA molecules comprising a sequence encoding a pseudorabies virus (PRV) glycoprotein selected from the group consisting of gI, gp50, and gp63, host cells transformed by said recombinant DNA molecule sequences, the gI, gp50 and gp63 polypeptides. The present invention also provides subunit vaccines for PRV, methods for protecting animals against PRV infection and methods for distinguishing between infected and vaccinated animals.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: January 9, 2001
    Assignee: Pharmacia & Upjohn Company
    Inventors: Erik Aivars Petrovskis, Leonard Edwin Post, James G. Timmins