Patents Represented by Attorney James E. R. Potter

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  • Recombinant human CSF-1 dimer and compositions thereof
    Patent number: 5861150
    Abstract: The present invention is directed to a biologically active CSF-1 dimer comprising a first CSF-1 monomer and a second CSF-1 monomer, wherein at least one of the monomers is truncated at the C-terminus after residue position 223. The dimers also include point mutations in one or both of the CSF-1 monomer. The invention also includes pharmaceutical compositions that comprise the CSF-1 dimer in a pharmaceutical excipient.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: January 19, 1999
    Assignee: Chiron Corporation
    Inventors: Robert Halenbeck, Kirston Koths, Cynthia Cowgill, Walter J. Laird