Patents Represented by Attorney James H. Harrington

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  • Format for minimizing interferences in chemiluminescent thin-film immunoassays
    Patent number: 6090568
    Abstract: A multilayer dry immunoassay element comprising 1) a spreading layer having a sample application area and a signal read area and 2) a separate receptor layer residing on 3) a radiation-transmissive support characterized in that the spreading layer contains a light absorbing material.
    Type: Grant
    Filed: August 4, 1997
    Date of Patent: July 18, 2000
    Assignee: Clinical Diagnostic Systems, Inc.
    Inventors: Richard Troconis Belly, Caroline Erdrich, Richard Calvin Sutton
  • Mutants of Myceliophthora laccase with enhanced activity
    Patent number: 5770419
    Abstract: The present invention relates to mutants of a blue multi-copper oxidase, comprising (a) a substitution of one or more amino acid residues with other amino acid residues, (b) an insertion of one or more amino acid residues and/or (c) a deletion of one or more amino acid residues, wherein the substitution, insertion or deletion is carried out at a position which is located no greater than 15 .ANG. from a Type I (T1) copper site. The present invention also relates to nucleic acid constructs comprising a nucleic acid sequence encoding the mutants of the present invention, host cells comprising the construct of the present invention, and methods for producing mutants of the present invention.
    Type: Grant
    Filed: August 30, 1996
    Date of Patent: June 23, 1998
    Assignee: Novo Nordisk Biotech, Inc.
    Inventors: Xu Feng, Randy M. Berka, Jill Angela Wahleithner