Abstract: There are provided amphiphilic biodegradable copolymers comprising a hydrophilic backbone with pendant aliphatic groups as the hydrophobic component. The polymers form nanoscale molecular aggregates in aqueous environments, which have hydrophobic interiors that are capable of solubilizing insoluble organic compounds such as drugs, vitamins, dyes, and imaging agents. The polymers optionally feature reactive functional groups that provide attachment points for antibodies, ligands, and other targeting moieties useful for the targeted delivery of drugs and imaging agents.
Type:
Grant
Filed:
January 19, 2006
Date of Patent:
May 8, 2012
Assignee:
AllExcel Inc.
Inventors:
Anil Diwan, Ann Louise Onton, Jayant G. Tatake
Abstract: A breakage-resistant form of separatory funnel or other laboratory glassware, such as addition funnel, flask, buret, or chromatography column, is provided. The glassware features an unbreakable plastic stem, preferably removably attached, below the glass stopcock in place of the usual glass stem.