Abstract: The present invention provides a combined needle and dilator comprising a needle having a head with an outer diameter greater than the outer diameter of the body of the needle and a dilating sheath carried about the needle and abutting the rearward needle portion of the needle head. The dilating sheath has a front portion with an outer diameter substantially equal to the outer diameter of the needle head to define, with the head, a generally smooth surface; a body portion with an outer diameter greater than that of the front portion; and a tapered portion disposed between the front and body portions. The tapered portion has an outer surface smoothly merging into the outer surfaces of the front portion and the body portion.

Abstract: A guide useful for guiding a catheter within a blood vessel is formed of a single length of shape memory alloy. The guide has a central portion of uniform diameter and substantially identical tapered end portions each terminating in enlarged diameter portions defining smoothly rounded beads which function to reduce trauma to the lumen of a blood vessel.

Abstract: A material heating oven for sterilizing items for use in a sterile environment or the like comprising a hot air supply device having a filter, a cool air supply device having a filter, an oven cavity separate from the hot air supply and cool air supply devices, and a dampering system for selectively drawing air from the hot air supply and cool air supply devices to regulate the temperature of the oven cavity. Both the hot air supply and cool air supply devices include independent air recirculation loops for maintaining substantially constant temperature airstreams from which selected quantities of air are exchanged with the oven cavity. The nearly constant temperature airstreams prevent the filters in the devices from being thermally stressed which may cause them to shed particles to the clean environment. An electrically controlled temperature control system is used to regulate the temperature of the airstream flowing through the hot air supply and cool air supply devices.

Abstract: A medical guide wire for insertion into body channels for accessing specific inner body areas without major surgery. The guide wire comprises an elongated, flexible guide having a core of a shape memory alloy, the guide utilizing the two-way memory properties of the shape memory alloy to impart tip-deflecting and rotational movement to the guide wire in response to a controlled thermal stimulus.

Abstract: To improve chip resistance of an alkyd-type electro-depositable coating composition, there may be added to the composition an ethylenically unsaturated, addition-polymerizable monomer or oligomer having a substantially linear backbone, having a molecular weight of at least about 150, and being reactive with fatty acid unsaturation of the alkyd.

Abstract: The biocompatibility of biomaterials having solid surfaces is improved through coating the same with biocompatible agents where the biocompatible agents are covalently bonded to the solid surface via a chemical linking moiety. The method for modifying the solid surface to improve biocompatibility employs molecules of a biocompatible agent and a chemical linking moiety possessing a photochemically reactive group capable upon activation of covalently bonding to the solid surface and possessing a different reactive group as capable upon activation of covalently bonding to separate molecules of the biocompatible agent. One of the groups is unresponsive to activation by a stimulus to which the other group is responsive.

Abstract: A method for reducing the occurrence of falsely elevated results in a peroxidase-catalyzed, enzyme assay is described. Interference in an assay caused by blood or bood products in a clinical specimen is eliminated or reduced by reacting the specimen with an oxidizing agent such as sodium hypochlorite, hydrogen peroxide or sodium meta-periodate.

Abstract: An easily produced, reliable mount for gems comprising a band (21, 22) embracing the periphery of the setting side of the gem (18), said band having a slit (15). At the upper edge of the band (21, 22), holding elements (19, 20) are disposed for the gem (18). Holding tongues (12, 13) disposed on the band (21, 22) and inclined outwardly and upwardly, serve to fix the mount in a carrier opening.

Abstract: A catheter useful in draining cerebrospinal fluid from the ventricles of a brain. The catheter utilizes a series of holes arranged in a helical pattern at the forward or ventricular end portion of the catheter. Exterior grooves may be provided in the ventricular end of the catheter within which the holes are protectively sheltered from contact with surrounding ventricular tissue. The catheter, and particularly its ventricular end, may be capable of elastic elongation upon insertion of a rigid stylet within the catheter, the diameter of the ventricular end portion become reduced in response to its axial elongation to facilitate disengagement of the catheter with the surrounding ventricular tissue to permit the catheter to be withdrawn.

Abstract: An organ preservation solution, particularly valuable in the preservation of mammalian hearts intended for transplantation, in aqueous solution, at least about 3% by weight of polypropylene glycol having an average molecular weight of at least about 15,000 daltons and being free of material retained by 10 micron filtration, a buffer buffering the pH of the solution perfusate to a value in the range of about 7.1 to about 7.5, and an impermeant composition for retarding the passage of water across cell membranes of an organ treated with the solution.

Abstract: A polypeptide transforming growth factor found in porcine platelets, having activity in the TGF-.beta. assay and a molecular weight of about 25 kDa. The factor is a heterodimer, one chain of which has an N-terminal sequence very different from human platelet TGF-.beta., and the other chain of which has an N-terminal sequence identical to that of human platelet TGF-.beta.. The factor is purified using gel filtration and reverse phase HPLC.

Abstract: A method is disclosed for reducing the propensity of a dairy cow to develop severe milk fever upon calving comprising administering thereto a composition comprising a water-soluble calcium compound and a complexing agent for serum phosphorus.

Abstract: Arthroscopic instrumentation for use in arthroscopic surgery and similar procedures. The instrumentation includes a cannula having a curved lumen and an elongated, flexible normally straight shape memory alloy probe. The probe is insertable into the lumen of the cannula, which in turn can be directed to a hard to reach operative site. The cannula causes the probe to bend as it passes the curves of the cannula, but the shape memory character of the probe causes the probe to exit the distal end of the cannula in a substantially straight orientation.

Abstract: An immunoassay procedure for the detection of chlamydia trachomatis antigen in a urogenital clinical specimen including a method for substantially eliminating the occurrence of false negative and false positive results of the immunoassay procedure. The method comprises treating a patent specimen with an aqueous solution having a final concentration of 0.1M NaOH or 0.1M KOH and then neutralizing the specimen-containing solution before conducting the immunoassay.

Abstract: An alkyd-type electrodepositable coating composition derived from the reaction of a base alkyd with ethylenically unsaturated monomers including an amine-functional monomer is provided with improved resistance to chipping by chemically incorporating in it by covalent bonding one or more chemical agents selected from the group of:(a) preformed elastomers having functional groups reactive with carboxyl or hydroxyl groups of acid and polyol alkyl precursors, and(b) an addition polymerizable monomer having primary and secondary ethylenic unsaturation.

Abstract: A liquid-retaining railroad car liner for lining the interiors of railroad cars enabling the cars to transport liquids. The liner serves as a bladder which may be carried by an open-topped railroad car enabling the car to be filled with liquid. The bladder, when empty, can be flattened and used as a waterproof tarpaulin to cover cargo carried by a railroad car thus protecting the cargo from the elements and helping to prevent spillage on railways.

Abstract: A method of producing multi-pane glass units having a non-air gas in the interpane space. The method includes the steps of assembling several glass units, each of which has a pair of spaced glass panes and a peripheral spacer. A separator device is interposed between one of the panes and the peripheral spacer of each of the units. When the units have been so assembled, a vacuum is drawn on the units in an evacuable chamber to remove substantially all of the air from the interpane spaces. The chamber is then refilled with a suitable gas, such as argon, to refill the interpane space of each of the units. The separator is then removed from the glass units, to close the opening between the pane and the peripheral spacer of each unit, thereby completely sealing the interpane space of each unit from the vacuum chamber environment. The units can then be removed from the vacuum chamber and further processed.

Abstract: A radiant heating system especially useful for floor heating is provided with a fluid flow apparatus that includes means for pumping a fluid such as water, a temperature-responsive actuator and a valve positionable within a valve housing in response to measured fluid temperature. The system includes heat transfer means, typically a tube embedded in the floor that receives heated fluid from the flow apparatus which in turn receives fluid at generally a higher temperature from a fluid heating apparatus such as a water boiler. The amount of heated fluid recirculated to the heat transfer means is controlled by the position of the valve in the valve housing.