Abstract: A method of determining at least one patient physiological parameter from an imaging procedure includes at least the steps of measuring time enhancement outputs for at least two different regions of interest, and determining at least one difference between the time enhancement outputs to provide a measure of the at least one patient physiological parameter. The physiological parameter can be a parameter of the cardiopulmonary system. It can also be the cardiac output, the blood volume in a region, a rate transfer term or a transit delay. A first time enhancement output may be measured in the ascending aorta or the descending aorta and a second time enhancement output may be measured in the pulmonary artery trunk.

Abstract: A system and method of extracting at least one time-value curve enables determination of a protocol for a patient in an imaging procedure. The method includes the step of determining a series of 0 through T M-dimensional data sets of pixel values of an imaged portion of the patient acquired using an imaging system. M and T are integers, and the 0 and T data sets correspond to sets at times t=0 and t=T, respectively. Other steps include: computing a predetermined number of correlated segments of the imaged portion corresponding to a number of regions of interest by computing a similarity metric of a time series of pixel values; computing the at least one time-value curve for at least one of those regions; and determining a protocol for a diagnostic scan using the imaging system based at least in part upon data from the at least one time value curve.

Abstract: A method of controlling an injector system for delivering a contrast enhancing fluid to a patient. The method includes the step of determining at least one patient transfer function for the patient based upon data specific to the patient, with the at least one patient transfer function providing a time enhancement output for a given input. The data specific to the patent may include at least one of an estimate of physiologic parameters of the patient, an estimate of anatomic parameters of the patient and an enhancement caused by an injection of the contrast enhancing fluid into the patient. Other steps involve: determining a desired time enhancement output; using the at least one patient transfer function to determine an injection procedure input; and controlling the injector system at least in part on the basis of the determined injection procedure input.

Abstract: A fluid connector system features a stopper and an extending section. Installable within an outlet of a fluid container, the stopper defines a passage therethrough. Defining air and fluid conduits, the extending section has a first abutment member threadably connectible thereto and a second abutment member affixed thereto. The extending section is adapted to be extended through the passage of the stopper when assembled thereto. When the first abutment member is tightened about the extending section, the first and second abutment members abut against the exterior and interior sides, respectively, of the stopper. With the stopper installed within the outlet and the extending section and the abutment members therewith assembled to the stopper thereby sealing the passage therein, fluid within the container may be extracted via the fluid conduit as air exterior to the container flows therein via the air conduct to displace the fluid being extracted from the container.

Abstract: An injection system includes an injector for injecting a fluid into a patient and a controller in operative communication with the injector for control thereof. The controller controls a diagnostic injection of the fluid based upon at least one mathematical model individualized to the patient. The model(s) are determined by collecting data corresponding to a time response curve resulting from at least one test injection of the fluid into the patient. The time response curve represents a response of a region of interest of the patient over time due to the fluid passing therethrough. An imaging system having such an injection system is also disclosed, as is a system for effecting a medical procedure. A method of delivering such a fluid to a patient using such an injection system is also disclosed, as is a method of modeling propagation of such a fluid in a patient.

Abstract: A method of coordinating an imaging procedure and an injection procedure, the method comprising the steps of providing an injector system having first and second pressurizing units for pressurizing a contrast medium and a diluent for injection into a patient; providing an imaging system for producing an image of an internal region of the patient from a signal resulting from energy applied to the patient; and providing a data interface interconnecting the injector and imaging systems for enabling exchange of digital information therebetween such that the digital information transmitted between the systems is usable to enable closed loop control of at least one of the injection and the imaging procedures during which the contrast medium and the diluent injected into the patient is adjustable so as to achieve a desired level of enhancement within the internal region of the patient of which the images are acquired during the imaging procedure.

Abstract: An occlusive guidewire system having an ergonomic handheld control mechanism and torqueable kink-resistant guidewire having a distally located inflatable balloon. The present invention provides convenient structure and overall mechanism for operation of a torqueable kink-resistant guidewire, including evacuation and inflation control of an occlusive balloon, and sealing and severing of a crimpable inflation tube which is in communication with an occlusive balloon. The torqueable kink-resistant guidewire includes a centrally located shaft which imparts robustness to the torqueable kink-resistant guidewire. An inflation lumen aligns within the torqueable kink-resistant guidewire for inflation of the balloon.

Abstract: An interface unit enables communication with an injector system that is used for pressurizing a fluid medium for injection into a patient during an injection procedure. The interface unit includes a processor and a storage unit. The processor controls operation of the interface unit and enables exchange of digital information between the interface unit and the injector system. The storage unit, under control of the processor, records the digital information gathered from the injector system during communication therewith. The digital information includes at least injection profile, history and dose data pertaining to the injection procedure. The processor enables at least the injection profile, history and dose data of the digital information recorded within the storage unit of the interface unit to be communicable to at least one of an imaging system linked thereto and an external device linked thereto.

Abstract: A disposable flow set for use with a pump includes a first administration tube, at least one tube-segment having a first end and a second end, the first end connected to the first administration tube, a second administration tube connected to the second end of the at least one tube-segment; and an identifying key member connected to the at least one tube-segment. The identifying key member includes a number of teeth that define a unique code, including a combination of location and width. The teeth fit into compatible niches located in the pump.

Abstract: A system for collecting, managing and disseminating information relating to medical procedures includes a central computer and a plurality of medical devices each in communication with an injector, a scanner, a hospital system and/or at least one other device. Each medical device receives (I) before a procedure is performed, patient identification information from a user interface, the scanner and/or the hospital system and (II) during and/or after the procedure, injection information from the injector and imaging study information from the scanner. Each medical device has an associated database for storing as a record therein the patient identification information, the injection information and the imaging study information for each procedure performed on each patient.

Abstract: A system for producing a contrast-enhanced medical image of a patient includes a source of a contrast or enhancement medium, a pressurizing unit in fluid connection with the source of contrast or enhancement medium, an energy source operable to apply energy to a region of the patient, an imaging unit providing a visual display of an internal view of the patient based upon a signal resulting from the energy applied to the region of the patient, and a control unit. In an embodiment, the signal is affected by a condition of the contrast or enhancement medium in the patient. To control the procedures, the control unit adjusts the condition of the contrast or enhancement medium in the patient based upon the signal. A communication interface preferably enables information between an injector subsystem and an imaging subsystem.

Abstract: A fluid injection apparatus includes at least one pressurizing mechanism and at least a first fluid container (for example, a syringe or a bulk container) operably associated with the at least one pressurizing mechanism. The first fluid container is adapted to contain a first fluid to be injected. The fluid injection apparatus also includes a controller operably associated with the at least one pressurizing mechanism. The controller includes a programming system to allow programming of an injection protocol including, for example, a plurality of phases. At least one parameter generator is provided to determine parameters of at least one of the plurality of phases of the protocol based at least in part upon a type of the injection procedure.

Abstract: A head coil for use with a parallel-imaging compatible MR system is disclosed, as is a method of making, and a neurovascular array (NVA) equipped with, same. The head coil includes conductive rings and rods configured to produce a plurality of electrically-adjacent primary resonant substructures about a birdcage-like structure, with each such primary resonant substructure including two rods neighboring each other and the short segment of each of the first and second rings interconnecting them. The primary resonant substructures are isolated from each other via a preamplifier decoupling scheme and an offset tuning scheme thereby enabling each primary resonant substructure (i) to receive an MR signal from tissue within its field of view and (ii) to be operatively couplable to one processing channel of the MR system for conveyance of the MR signal received thereby (iii) while being simultaneously decoupled from the other primary resonant substructures.

Abstract: An intracavity probe for use with an MR system allows images or spectra of a region of interest within a cavity of a patient to be obtained. The probe includes a shaft, a balloon at one end thereof, and a coil loop within the balloon. The coil loop preferably includes two drive capacitors and a tuning capacitor, all of which in series. A junction node between the drive capacitors serves as a ground for electrically balancing the coil loop. Diametrically opposite the junction node, the tuning capacitor enables the coil loop to resonate at the operating frequency of the MR system. Across each drive capacitor is connected an output cable having an electrical length of SL+n(?/4). The output cables terminate in a plug that is used to connect the coil loop to an interface device for the intracavity probe.

Abstract: An apparatus for holding a fluid container, such as a syringe or a vial, is provided for securing the container in an upside down or other suitable position for use in various medical procedures such as those of the type that involve use of a medical pump. The fluid container holding apparatus is capable of operatively connecting to any of a number of support structures including a wall, ceiling, desk, table, post, hangar, or IV stand. A fluid delivery system including such a fluid container, and a fluid conduit, such as IV tubing, may include the fluid container holding apparatus of the present invention.

Abstract: An MR system features an intracavity probe and associated interface device. The probe includes a shaft, a balloon at one end thereof, and a coil loop within the balloon. The loop has two drive capacitors and a tuning capacitor, all of which in series. A junction node between the drive capacitors serves as a ground for electrically balancing the loop. Diametrically opposite the node, the tuning capacitor enables the loop to resonate at the operating frequency of the MR system. The interface allows the MR system to couple the loop to a port of the MR system during a receive cycle thereof and decouple it from the port during a transmit cycle thereof. With its balloon inserted and inflated within a cavity of a patient, the probe allows the MR system to generate images and/or spectra of the region of interest using the MR signals received by the loop.

Abstract: An injector for injection a fluid into a patient, including: a first pressurizing mechanism adapted to operatively connect with a first fluid container to pressurize fluid therein; at least a second pressurizing mechanism to operatively connect with a second fluid container to pressurize a fluid therein; a single drive; and a transmission to control how power from the drive is distributed to the first pressurizing mechanism of the first container and to the second pressurizing mechanism of the second container to control injection of fluid from the first container and from the second container. The drive can, for example, be an electric motor or other drive.

Abstract: A device for injection of a fluid into a patient includes a container adapted to hold the fluid and defining an outlet through which the fluid can exit the container. A pressurizing mechanism is in connection with the container for pressurizing the fluid, and an actuator is in fluid connection with the outlet. The actuator has a first state in which fluid is prevented from flowing through the outlet and a second state in which fluid can flow through the outlet. The injection device further includes a flow regulator to control the flow rate of fluid in fluid connection with the outlet. The container, the pressurizing mechanism, the actuator and the flow regulator can be MR compatible, thereby making the device suitable for use in or near the bore of an MR scanner.

Abstract: A method of substituting an MRI incompatible pump for delivering fluid to a patient with an MRI compatible pump, both pumps being microprocessor controlled. The first pump operates upon administration tubing for pumping fluid from a source thereof to the patient. The method includes the steps of: providing the second pump to be substituted for the first pump; providing second tubing having a portion thereof that is operable to function with the second pump; connecting the second tubing to the administration tubing to establish an altered fluid path from the source to the patient, the altered path including portions of both the administration and second tubing; placing the second pump for operation upon the second tubing to enable the second pump to pump the fluid through the altered path according to programming thereof; and disconnecting the first pump from the administration tubing before bringing the patient into the MRI environment.

Abstract: A battery charger system, for use with an injector system, comprises a power supply and a battery pack. The power supply converts AC power to DC power. The battery pack includes a battery and a charging module. The module monitors the operating mode of the injector system. When the battery pack is disconnected from the injection control unit, the module enables the power supply to charge the battery with DC power. When the battery pack is connected to the injection control unit: (A) upon detecting the injector system in an idle mode, the module routes DC power from the power supply to both the battery for charging thereof and the injection control unit for operation thereof; and (B) upon detecting the injector system in a non-idle mode, the module prevents the power supply from charging the battery and enables the battery to provide DC power to the injection control unit.