Patents Represented by Attorney Jane C. McLaughlin

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  • 3'-expression enhancing fragments and method
    Patent number: 4910141
    Abstract: The invention concerns a method for extending the half-life of mRNAs. The half-life extension is conferred upon the mRNA by a co-transcribed positive retroregulatory element which is ligated to the 3' end of the DNA sequence encoding the RNA. RNAs having an extended half-life conferred by a co-transcribed positive retroregulatory element are also claimed.
    Type: Grant
    Filed: March 29, 1985
    Date of Patent: March 20, 1990
    Assignee: Cetus Corporation
    Inventors: Hing C. Wong, Shing Chang