Abstract: A recombinant DNA vector is provided that expresses exons of genomic DNA fragments that are inserted into the vector. The vector contains a promoter and a genomic DNA fragment so characterized and configured that the vector, upon transcription in a transfected eukaryotic cell culture, expresses the corresponding RNA segment of the genomic DNA fragment free of any intron.
Type:
Grant
Filed:
May 23, 1995
Date of Patent:
November 4, 1997
Assignee:
Genentech, Inc.
Inventors:
Daniel J. Capon, Richard M. Lawn, Gordon A. Vehar, William I. Wood