Abstract: Certain variants of Lipolase (wild-type Humicolalanuginosa lipase) have a particularly good first-wash performance in a detergent solution. The variants should comprise one or more substitutions with positive amino acids near the N-terminal in the three-dimensional structure. The variants should further comprise a peptide addition at the C-terminal and/or should meet certain limitations on electrically charged amino acids at positions 90-101 and 210.
Type:
Grant
Filed:
March 30, 2000
Date of Patent:
September 6, 2005
Assignee:
Novozymes A/S
Inventors:
Jesper Vind, Allan Svendsen, Shamkant Anant Patkar, Kim Vilbour Andersen, Dorte Aaby Halkier, Kirsten Bojsen