Abstract: The present application relates to a group of novel substituted pentose and hexose monosaccharide derivatives, not previously disclosed, which exhibit potent anti-cell adhesion and anti-inflammatory activities. Methods of preparation, pharmaceutical compositions containing the compounds and methods of treatment, suppression and prevention of cell adhesion mediated chronic inflammatory disorders are also described.
Type:
Grant
Filed:
October 1, 1999
Date of Patent:
December 11, 2001
Assignee:
Ranbaxy Laboratories Limited
Inventors:
Sudershan K. Arora, Madan P. Tanwar, Jang P. Gupta, Geeta Sharma