Abstract: A refractory boride body or coating made of a boride of titanium, chromium, vanadium, ziconium, hafnium, niobium, tantalum, molybednum and cerium is produced from a slurry of the refractory boride or a precursor in a collidal carrier preferably composed of two more different grades of the same colloidal carrier selected from colloidal alumina, yttria, ceria, thoria, zirconia, magnesia, lithia, monoaluminum phosphate and cerium acetate. The slurry can also comprise an organic additive selected from polyvinyl alcohol; polyacrylic acid; hydroxyy propyl methyl cellulose; polythylene glycol; ethylene glycol, butyl benzyl phthalate; ammonium polymethacrylate and mixtures thereof. The retractory boride body or coated body is useful as a component of aluminum electrowinning cells.

Abstract: A non-carbon, metal-based, high temperature resistant, electrically conductive and electrochemically active anode of a cell for the production of aluminum has a metal-based oxidation-resistant substrate to which an adherent multi-layer coating is applied prior to its immersion into the electrolyte and start up of the electrolysis by connection to the positive current supply. The multi-layer coating is obtainable from one or more applied layers selected from: a liquid solution, a dispersion in a liquid or a paste, a suspension in a liquid or a paste, and a pasty or non-pasty slurry, and combinations thereof, with or without heat treatment between two consecutively applied layers. At least one layer of the multi-layer coating contains a polymeric and/or a colloidal carrier. The coating is after final heat treatment electrically conductive and has during operation in the cell an electrochemically active surface for the oxidation of oxygen ions present at the surface of the anode.

Abstract: Novel piperzine derivatives substituted on one nitrogen by an aromatic system and on the other nitrogen by (2,5-dioxopyrrolidin)-1-yl) alkanes or (2,6-dioxopiperidin-1-yl) alkanes have been found to exhibit selective &agr;1A adrenergic activity. The compounds are useful for treatment of disease conditions, such as peripheral vascular disease, congestive heart failure, hypertension and especially benign prostatic hypertrophy.

Abstract: Novel piperzine derivatives substituted on one nitrogen by an aromatic system and on the other nitrogen by (2,5-dioxopyrrolidin)-1-yl) alkanes or (2,6-dioxopiperidin-1-yl) alkanes have been found to exhibit selective &agr;1A adrenergic activity. The compounds are useful for treatment of disease conditions, such as peripheral vascular disease, congestive heart failure, hypertension and especially benign prostatic hypertrophy.

Abstract: Novel piperzine derivatives substituted on one nitrogen by an aromatic system and on the other nitrogen by (2,5-dioxopyrrolidin)-1-yl) alkanes or (2,6-dioxopiperidin-1-yl) alkanes have been found to exhibit selective &agr;1A adrenergic activity. The compounds are useful for treatment of disease conditions, such as peripheral vascular disease, congestive heart failure, hypertension and especially benign prostatic hypertrophy.

Abstract: A cell of advanced design for production aluminum by the electrolysis of an aluminum compound dissolve in a molten ectrolyte, has a cathode (30) of drained configuration, and at least one non-carbon anode (10) facing the cathode both covered by the electrolyte (54). The upper part of the cell contains a removable thermic insulating cover (60) placed just above the level of the electrolyte (54). Preferably, the cathode (30) comprises a cathode mass (32) supported by a cathode carrier (31) made of electrically conductive material which serves also for the uniform distribution of electric current feeders (42) which connect the cathode carrier (31) to the negative busbars.

Abstract: An adherent protective coating of a refractory material is produced on the surface of carbonaceous, refractory, ceramic, metallic or other materials serving as components of electrolytic cells operating at high temperature, by applying to such surfaces a well chosen micropyretic reaction layer from a slurry, which when dried is ignited to initiate a self-sustaining micropyretic reaction, along a combustion front, to produce condensed matter forming such refractory protective adherent coating. The slurry is preferably applied in several layers, the first layer(s) to facilitate adherence and the last layer(s) to provide protection, and may contain some preformed non-reactant materials. The electrolytic cells whose components require such coatings are especially those operating at high temperature with a molten salt electrolyte, particularly those for the production of metals, aluminium being the most important.

Abstract: There is described a process for the preparation of a pure amorphous form of cefuroxime axetil which involves dissolving crystalline cefuroxime axetil in acetic acid including at least 5% v/v water and recovering said amorphous form of cefuroxime axetil from the solution by the addition of additional water, the solution being added all at once to the additional water being present in a volume which is sufficient to precipitate said amorphous cefuroxime axetil.

Abstract: A non-carbon metal-based anode of a cell for the electrowinning of aluminium comprising an electrically conductive metal substrate resistant to high temperature, the surface of which becomes passive and substantially inert to the electrolyte, and a coating adherent to the metal substrate making the surface of the anode electrochemically active for the oxidation of oxygen ions present at the electrolyte interface. The substrate metal may be selected from nickel, cobalt, chromium, molybdenum, tantalum and the Lanthanide series. The active constituents of the coating are for example oxides such as spinels or perovskites, oxyfluorides, phosphides or carbides, in particular ferrites. The active constituents may be coated onto the substrate from a slurry or suspension containing colloidal material and the electrochemically active material.

Abstract: A cell for the electrowinning of aluminium comprising one or more anodes, each having a metal-based anode substrate, comprising a metal core covered with an metal layer, an oxygen barrier layer, one or more intermediate layers and an iron layer. The anode substrate is covered with an electrochemically active iron oxide-based outside layer, particularly a hematite-based layer, which remains dimensionally stable during operation in a cell by maintaining in the electrolyte a sufficient concentration of iron species. The cell operating temperature is sufficiently low so the required concentration of iron species in the electrolyte is limited by the reduced solubility of iron species in the electrolyte at the operating temperature, limiting the contamination of the product aluminium by iron to an acceptable level. The iron oxide-based layer is an applied coating or an oxidised surface of a substrate, the surface of which contains iron.

Abstract: A non-carbon, metal-based, high temperature resistant, electrically conductive and electrochemically active anode of an aluminum production cell has a metal-based substrate having an adherent coating applied prior to its immersion into the electrolyte and start up of the electrolysis. The coating is obtainable from one or more layers applied from: a liquid solution, a dispersion or suspension in a liquid or a paste, a pasty or non-pasty slurry, and combinations thereof with or without one or more further applied layers, with or without heat treatment between two consecutively applied layers when at least two layers are applied.

Abstract: Method and cell component for the electrowinning of aluminum by the electrolysis of alumina dissolved in a molten fluoride electrolyte comprises a porous micropyretic reaction product of nickel, aluminum, iron, copper and at least one additive element selected from silicon, tin zinc, vanadium, indium, hafnium, tungsten, elements from the lanthanide series starting from praesodymium, and misch metal. The micropyretic reaction product contains metallic and intermetallic phases, with a composite oxide surface produced in-situ by anodic polarization of the porous micropyretic reaction product in a molten fluoride electrolyte containing dissolved alumina, or by high temperature treatment in an oxidizing gas. The composite oxide surface usually comprises an iron-rich relatively dense outer portion and an aluminate-rich relatively porous inner portion.

Abstract: A method of coating an electronically conductive and heat resistant substrate of an anode of a cell for the electrowinning of metals, in particular a cell for the electrowinning of aluminium, to protect and make the surface of the anode active for the oxidation of the oxygen ions present in the electrolyte. The method comprises applying onto the substrate a slurry comprising at least one oxide or oxide precursor as a non-dispersed but suspended particulate in a colloidal and/or inorganic polymeric carrier. The applied-slurry is then solidified and made adherent to the substrate upon heat treatment to form an adherent, protective, predominantly oxide-containing coating. The colloidal and/or inorganic polymeric carrier may comprise at least one of alumina, ceria, lithia, magnesia, silica, thoria, yttria, zirconia, tin oxide and zinc oxide. The oxide of the coating may be a chromite or a ferrite, such as a ferrite selected from cobalt, copper, manganese, nickel and zinc.

Abstract: A cell for the production of aluminium by the electrolysis of an aluminium compound dissolved in a molten electrolyte, in which an outer mechanical structure forming an outer shell (21) houses therein one or more inner electrically-conductive cathode holder shells or plates (31) which contain a cathode mass (32) and is/are connected electrically to the busbar. The cathode mass (32) has an aluminium-wettable top surface (37), preferably at a slope forming a drained cathode. The inner cathode holder shell or shells (31) is/are separated from the outer shell (21) by an electric and thermic insulation (40), the cathode holder shell(s) (31) also serving to distribute current uniformly to the cathode mass (32). The or each cathode (30) formed by the cathode holder shell (31) and cathode mass (32) is removable from the cell as a unit.

Abstract: This invention relates to a process of mixing of crystalline cefuroxime axetil with amorphous cefuroxime axetil for the preparation of a bioavailable oral dosage form comprising of amorphous cefuroxime axetil containing from 7 to 25% crystalline cefuroxime axetil.

Abstract: A method of protecting a cathode during the start-up procedure of an aluminum electrowinning cell where the cathode is optionally coated with an aluminium-wettable refractory material and when in use, aluminium is produced thereon. The start-up procedure comprises applying, before preheating the cell, one or more start-up layers in intimate contact on the aluminium-wettable refractory coating which form(s) a temporary protection against damage of chemical and/or mechanical origin to the aluminium-wettable coating; this temporary protection being eliminated before or during the initial normal cell operation. The temporary protection layers may be obtained from at least one pliable aluminium foil having a thickness of less than 0.1 mm and/or an applied aluminium-containing metallization, optionally in combination with inter alia a boron-containing solution, a polymer, a phosphates of aluminium-containing solution, or a colloid that gels while preheating the cell, or combinations thereof.

Abstract: A process for the preparation of the esters of 1,8-disubstituted-1,3,4,9-tetrahydropyrano (3,4-b)-indole-1-acetic acid is delineated.

Abstract: This invention relates to a bioavailable oral dosage form comprising of amorphous cefuroxime axetil containing from 7 to 25% crystalline cefuroxime axetil.

Abstract: A stable solid pharmaceutical composition in the form of tablets or capsules is disclosed including enalapril maleate as active ingredient and pharmaceutically acceptable excipients wherein at least one excipient is maleic acid or other edible desiccants.

Abstract: Carbon-containing components of cells for the production of aluminium by the electrolysis of alumina dissolved in a cryolite-based molten electrolyte are protected from attack by liquid and/or gaseous components of the electrolyte in the form of elements, ions or compounds, by a refractory boride coating applied from a slurry composed of pre-formed particulate refractory boride in a colloidal carrier which is dried and heated to consolidate the coating.