Patents Represented by Attorney Jeffrey A. McKinney

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  • Conjugates of biological substances
    Patent number: 7989638
    Abstract: Chemically reactive carbocyanine dyes that are intramolecularly crosslinked between the 1-position and 3?-position, their bioconjugates and their uses are described. 1,3?-crosslinked carbocyanines are superior to those of conjugates of spectrally similar 1,1?-crosslinked or non-crosslinked dyes. The invention includes derivative compounds having one or more benzo nitrogens.
    Type: Grant
    Filed: July 12, 2010
    Date of Patent: August 2, 2011
    Assignee: AnaSpec Incorporated
    Inventors: Zhenjun Diwu, Jianheng Zhang, Yi Tang, Xiang Guobing
  • Dye conjugates of nucleotides and other biological substances
    Patent number: 7985552
    Abstract: Chemically reactive carbocyanine dyes that are intramolecularly crosslinked between the 1-position and 3?-position, their bioconjugates and their uses are described. 1,3?-crosslinked carbocyanines are superior to those of conjugates of spectrally similar 1,1?-crosslinked or non-crosslinked dyes. The invention includes derivative compounds having one or more benzo nitrogens.
    Type: Grant
    Filed: September 1, 2010
    Date of Patent: July 26, 2011
    Assignee: AnaSpec Incorporated
    Inventors: Zhenjun Diwu, Jianheng Zhang, Yi Tang, Xiang Guobing
  • Conversational user interface that mimics the organization of memories in a human brain
    Patent number: 7805309
    Abstract: A conversational user interface (CUI) is implemented in a computer by mimicking the organization and retrieval of linguistic memories of human conversation. To mimic the organization of linguistic memories in a human brain, the artificial memories are stored as sequences of patterns, are stored in invariant form, are organized hierarchically, and are recalled auto-associatively. To mimic the recall of linguistic memories in a human brain, the same algorithm performs the recall of the various memories. Each artificial memory is a pairing of the invariant representation and an associated responsive message. When a received utterance is determined to match the invariant representation of a memory, the memory is evoked and the associated responsive message is presented to the person.
    Type: Grant
    Filed: February 15, 2006
    Date of Patent: September 28, 2010
    Assignee: Celf Corporation
    Inventor: Carl Edward Carpenter
  • Reactive 1,3?-crosslinked carbocyanine
    Patent number: 7465810
    Abstract: Chemically reactive carbocyanine dyes that are intramolecularly crosslinked between the 1-position and 3?-position, their bioconjugates and their uses are described. 1,3?-crosslinked carbocyanines are superior to those of conjugates of spectrally similar 1,1?-crosslinked or non-crosslinked dyes. The invention includes derivative compounds having one or more benzo nitrogens.
    Type: Grant
    Filed: October 21, 2005
    Date of Patent: December 16, 2008
    Assignee: AnaSpec, Inc.
    Inventors: Zhenjun Diwu, Jianheng Zhang, Yi Tang, Xiang Guobing