Abstract: A method for treating asthma in a patient using an agent selected from the group consisting of:(a) an antibody capable of binding to ELAM-1;(b) a fragment of the antibody (a), the fragment being capable of binding to ELAM-1;(c) ELAM-1, being substantially free of natural contaminants;(d) a functional derivative of ELAM-1;(e) an antibody capable of binding to an ELAM-1 receptor;(f) a fragment of the antibody (e), the fragment being capable of binding to an ELAM-1 receptor;(g) an ELAM-1 receptor, being substantially free of natural contaminants; and .(h) a functional derivative of an ELAM-1 receptor.
Type:
Grant
Filed:
July 19, 1995
Date of Patent:
December 1, 1998
Assignee:
Boehringer Ingelheim
Inventors:
Robert H. Gundel, Craig D. Wegner, L. Gordon Letts, C. Wayne Smith
Abstract: The invention relates to a method of identifying the individual autosomal and sex chromosomes of a human karyotype through the use of a set of combinatorially labeled oligonucleotide probes each member thereof: (i) having a predetermined label distinguishable from the label of any other member of said set, and (ii) being capable of specifically hybridizing with one predetermined autosomal or sex chromosome of a human karyotype.
Type:
Grant
Filed:
May 1, 1996
Date of Patent:
August 11, 1998
Assignee:
BioRad Laboratories, Inc.
Inventors:
Franklin R. Witney, David M. Heffelfinger
Abstract: The invention relates to a set of combinatorially labeled oligonucleotide probes each member thereof: (i) having a predetermined label distinguishable from the label of any other member of said set, and (ii) being capable of specifically hybridizing with one predetermined autosomal or sex chromosome of a human karyotype, and to the use of such molecules to identify the individual autosomal and sex chromosomes of a human karyotype.
Type:
Grant
Filed:
May 1, 1996
Date of Patent:
June 2, 1998
Assignee:
Yale University
Inventors:
David C. Ward, Michael Speicher, Stephen Gwynn Ballard