Abstract: The invention provides segments of HSV-1 and HSV-2 glycoprotein B which include antigenic epitopes in the gB amino-proximal region that react with human antibodies in a type-specific manner, and epitopes in the gB carboxy-proximal region that cross-react with HSV-1 and HSV-2 antibodies.
Type:
Grant
Filed:
April 19, 1996
Date of Patent:
March 6, 2001
Assignee:
University of New Mexico
Inventors:
Diane E. Goade, Richard Bell, Steven Jenison