Patents Represented by Attorney Jennifer Chapman

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  • Use of zolendronate for the manufacture of a medicament for the treatment of bone metabolism diseases
    Patent number: 8324189
    Abstract: A method of intravenously administering a bisphosphonate to a patient in need of bisphosphonate treatment comprising intravenously administering 4 mg of 2-(imidazol-1yl)-1-hydroxyethane-1,1-diphosphonic acid (zoledronic acid) or a pharmaceutically acceptable salt thereof over a period of 15 minutes to a patient in need of said treatment.
    Type: Grant
    Filed: November 8, 2006
    Date of Patent: December 4, 2012
    Assignee: Novartis Pharmaceuticals Corporation
    Inventors: Bruno Galli, Horst F Schran, John J Seaman
  • Rapamycin assay
    Patent number: 8039599
    Abstract: Monoclonal antibodies to rapamycin and to 40-O-alkylated derivatives of rapamycin are provided, together with novel haptens, immunogenic conjugates, and processes for making them and assay kits for using them.
    Type: Grant
    Filed: June 2, 2000
    Date of Patent: October 18, 2011
    Assignee: Novartis AG
    Inventors: Richard Sedrani, Valerie Quesniaux
  • Rapamycin assay
    Patent number: 8039600
    Abstract: Monoclonal antibodies to rapamycin and to 40-O-alkylated derivatives of rapamycin are provided, together with novel haptens, immunogenic conjugates, and processes for making them and assay kits for using them.
    Type: Grant
    Filed: August 20, 2001
    Date of Patent: October 18, 2011
    Assignee: Novartis AG
    Inventors: Richard Sedrani, Valerie Q Ryffel
  • Microparticles comprising somatostatin analogues
    Patent number: 7759308
    Abstract: Disclosed are microparticles comprising a somatostatin analogue embedded in a biocompatible pharmacologically acceptable polymer matrix for a long acting release and pharmaceutical compositions comprising such microparticles.
    Type: Grant
    Filed: November 12, 2004
    Date of Patent: July 20, 2010
    Assignee: Novartis AG
    Inventors: Markus Ahlheim, Michael Ausborn, Olivier Lambert, Marc Riemenschnitter
  • Process for the manufacture of organic compounds
    Patent number: 7572917
    Abstract: A method for preparing an alkali metal salt comprising: (a) condensing a disilyloxydiene with an aldehyde in the presence of a titanium (IV) catalyst in an inert solvent to form a 5(S)-hydroxy-3-ketoester; (b) reducing the 5(S)-hydroxy-3-ketoester to a 3(R),5(S)-dihydroxyester in the presence of a di(lower alkyl)methoxyborane; and (c) hydrolyzing the 3(R),5(S)-dihydroxyester in the presence of an aqueous base to form an alkali metal salt.
    Type: Grant
    Filed: July 14, 2004
    Date of Patent: August 11, 2009
    Assignee: Novartis AG
    Inventors: Guang-Pei Chen, Prasad K Kapa, Eric M Loeser, Ulrich Beutler, Werner Zaugg, Michael J Girgis