Abstract: The invention provides various antibodies that bind to lymphotoxin-?, methods for making such antibodies, compositions and articles incorporating such antibodies, and their uses in treating, for example, an autoimmune disorder. The antibodies include murine, chimeric, and humanized antibodies.
Type:
Grant
Filed:
February 11, 2011
Date of Patent:
July 10, 2012
Assignee:
Genentech, Inc.
Inventors:
Camellia W. Adams, Jane L. Grogan, Austin L. Gurney, Krista McCutcheon
Abstract: Novel anti-NRP1 antibodies and variants thereof having unique structural and functional characteristics are disclosed. Also provided are uses of the antibodies in research, diagnostic and therapeutic applications.