Patents Represented by Attorney Jennifer K. Johnson

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  • Tryptase-like polypeptide ztryp1
    Patent number: 6514741
    Abstract: The present invention relates to polynucleotide and polypeptide molecules for mouse ztryp1, a novel member of the serine protease family of proteins. The polynucleotides encoding mouse ztryp1 can be used to identify a human ortholog or to create a mouse model associated with human disease states. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.
    Type: Grant
    Filed: August 9, 2000
    Date of Patent: February 4, 2003
    Assignee: ZymoGenetics, Inc.
    Inventors: Scott R. Presnell, David W. Taft
  • Human thyroid protein ZSIG45
    Patent number: 6500925
    Abstract: The present invention relates to polynucleotide and polypeptide molecules for zsig45, a novel human protein expressed in thyroid. The polypeptides, and polynucleotides encoding them, may be used for detecting human disease states and chromosomal abnormalities, and as a therapeutic. The present invention also includes antibodies to the zsig45 polypeptides.
    Type: Grant
    Filed: March 10, 2000
    Date of Patent: December 31, 2002
    Assignee: ZymoGenetics, Inc.
    Inventors: Theresa A. Deisher, Paul O. Sheppard
  • Antibodies and methods of making antibodies to human thyroid protein zsig45
    Patent number: 6486304
    Abstract: The present invention relates to polynucleotide and polypeptide molecules for zsig45, a novel human protein expressed in thyroid. The polypeptides, and polynucleotides encoding them, may be used for detecting human disease states and chromosomal abnormalities, and as a therapeutic. The present invention also includes antibodies to the zsig45 polypeptides.
    Type: Grant
    Filed: March 10, 2000
    Date of Patent: November 26, 2002
    Assignee: Zymogenetics, Inc.
    Inventors: Theresa A. Deisher, Paul O. Sheppard
  • Ring finger protein zapop3
    Patent number: 6440697
    Abstract: The present invention relates to polynucleotide and polypeptide molecules for zapop3, a novel human member of the RING finger protein family. The polypeptides, and polynucleotides encoding them, may be used for detecting human chromosomal abnormalities. The present invention also includes antibodies to the zapop3 polypeptides.
    Type: Grant
    Filed: November 4, 1999
    Date of Patent: August 27, 2002
    Assignee: ZymoGenetics, Inc.
    Inventors: Domenick Venezia, Angelika Grossmann
  • Human 2-19 protein homologue, z219a
    Patent number: 6388064
    Abstract: The present invention relates to polynucleotide and polypeptide molecules for z219a, a novel member of the human 2-19 protein family. The polypeptides, and polynucleotides encoding them, may be used for detecting human chromosomal abnormalities. The present invention also includes antibodies to the z219a polypeptides.
    Type: Grant
    Filed: October 6, 1998
    Date of Patent: May 14, 2002
    Assignee: ZymoGenetics, Inc.
    Inventors: Darrell C. Conklin, Hal Blumberg
  • Secreted salivary ZSIG63 Polypeptide
    Patent number: 6331413
    Abstract: The present invention relates to polynucleotide and polypeptide molecules for zsig63, a novel secreted salivary protein. The polypeptides, and polynucleotides encoding them, may exhibit anti-microbial activity and may be used in the study or treatment of microbial infections. The polynucleotides encoding zsig63, are located on chromosome 4, and can be used to identify a region of the genome associated with human disease states. The present invention also includes antibodies to the zsig63 polypeptides.
    Type: Grant
    Filed: March 17, 2000
    Date of Patent: December 18, 2001
    Assignee: ZymoGenetics, Inc.
    Inventors: David A. Adler, Paul O. Sheppard
  • Human thyroid protein zsig45
    Patent number: 6140084
    Abstract: The present invention relates to polynucleotide and polypeptide molecules for zsig45, a novel human protein expressed in thyroid. The polypeptides, and polynucleotides encoding them, may be used for detecting human disease states and chromosomal abnormalities, and as a therapeutic. The present invention also includes antibodies to the zsig45 polypeptides.
    Type: Grant
    Filed: December 1, 1998
    Date of Patent: October 31, 2000
    Assignee: ZymoGenetics, Inc.
    Inventors: Theresa A. Deisher, Paul O. Sheppard
  • Human prohormone convertase 4
    Patent number: 6127162
    Abstract: The present invention provides polynucleotide and polypeptide molecules for a novel human prohormone convertase 4. The polynucleotides encoding human prohormone convertase 4, are located on chromosome 19, and may, for example, be used to identify a region of the genome associated with human disease states. The present invention also includes methods for producing the protein and antibodies thereto.
    Type: Grant
    Filed: August 6, 1999
    Date of Patent: October 3, 2000
    Assignee: ZymoGenetics, Inc.
    Inventors: Si Lok, Stephen R. Jaspers
  • Human prohormone convertase 4
    Patent number: 6100041
    Abstract: The present invention provides polynucleotide and polypeptide molecules for a novel human prohormone convertase 4. The polynucleotides encoding human prohormone convertase 4, are located on chromosome 19, and may, for example, be used to identify a region of the genome associated with human disease states. The present invention also includes methods for producing the protein and antibodies thereto.
    Type: Grant
    Filed: August 6, 1999
    Date of Patent: August 8, 2000
    Assignee: ZymoGenetics, Inc.
    Inventors: Si Lok, Stephen R. Jaspers
  • Human prohormone convertase 4
    Patent number: 6013503
    Abstract: The present invention provides polynucleotide and polypeptide molecules for a novel human prohormone convertase 4. The polynucleotides encoding human prohormone convertase 4, are located on chromosome 19, and may, for example, be used to identify a region of the genome associated with human disease states. The present invention also includes methods for producing the protein and antibodies thereto.
    Type: Grant
    Filed: May 1, 1998
    Date of Patent: January 11, 2000
    Assignee: ZymoGenetics, Inc.
    Inventors: Si Lok, Stephen R. Jaspers
  • Human amyloid protein precursor homolog and kunitz-type inhibitor
    Patent number: 5935854
    Abstract: The present invention provides isolated DNA molecules comprising a DNA segment encoding a novel human amyloid protein precursor homologue and novel Kunitz-type inhibitors. Also provided are DNA constructs comprising a first DNA segment encoding a novel human amyloid protein precursor homologue or a novel Kunitz-type inhibitor wherein said first DNA segment is operably linked to additional DNA segments required for the expression for the first DNA segment, as well as host cells containing such DNA constructs and methods for producing proteins from the host cells.
    Type: Grant
    Filed: April 18, 1995
    Date of Patent: August 10, 1999
    Assignee: ZymoGenetics, Inc.
    Inventors: Cindy A. Sprecher, Donald C. Foster, Kjeld E. Norris