Patents Represented by Attorney, Agent or Law Firm Jill A. Mello
  • Manganese superoxide dismutase regulatory elements and uses thereof
    Patent number: 6800458
    Abstract: A novel transcriptional regulatory element which was isolated from the MnSOD gene and which exhibits promoter-enhancer activity is disclosed. The promoter-enhancer activity of the element is further modulated by inflammatory mediators to regulate transcription. Methods of using the promoter-enhancer element to regulate gene expression, and therapeutic uses involving the promoter-enhancer element are also described.
    Type: Grant
    Filed: August 28, 2001
    Date of Patent: October 5, 2004
    Assignee: University of Florida
    Inventors: Harry S. Nick, Richard Rogers, John F. Valentine