Abstract: The present application describes inhibitors of factor Xa with a neutral P1 specificity group of formula I:
or pharmaceutically acceptable salt forms thereof, wherein R and E may be groups such as methoxy and halo.
Type:
Grant
Filed:
May 16, 2002
Date of Patent:
August 5, 2003
Assignee:
Bristol-Myers Squibb Company
Inventors:
Robert A. Galemmo, Jr., Celia Dominguez, John M. Fevig, Qi Han, Patrick Y. Lam, Donald J. P. Pinto, James R. Pruitt, Mimi L. Quan