Patents Represented by Attorney Joanee M. Giesser

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  • Cell culture of hepatitis A virus
    Patent number: 5514376
    Abstract: Hepatitis A virus is attenuated in virulence by in vitro passage in susceptible cell cultures, without prior passage in a subhuman primate. This process results in a live, attenuated hepatitis A virus vaccine suitable for human disease prevention.
    Type: Grant
    Filed: February 10, 1993
    Date of Patent: May 7, 1996
    Assignee: Merck & Co., Inc.
    Inventors: Paula A. Giesa, Philip J. Provost, Maurice R. Hilleman