Patents Represented by Attorney Joanne R. Dehlinger & Associates Petithory

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  • Antitumor therapy using ovine or bovine interferon-tau
    Patent number: 5958402
    Abstract: The invention provides antitumor therapeutic methods employing bovine or ovine interferon-tau (IFN-.tau.) proteins and polypeptides. The IFN-.tau. proteins exhibit the antiviral and antiproliferative properties characteristic of type I interferons. An advantage of the invention is that IFN-.tau. has essentially no cytotoxic effects on treated cells as does, for example, IFN-.alpha..
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: September 28, 1999
    Assignee: University of Florida
    Inventors: Fuller Warren Bazer, Howard Marcellus Johnson, Carol Hanlon Pontzer, Troy Lee Ott, Gino Van Heeke
  • Antiviral therapy using ovine or bovine interferon-tau
    Patent number: 5942223
    Abstract: The invention provides antiviral therapeutic methods employing bovine or ovine interferon-tau (IFN-.tau.) proteins and polypeptides. The IFN-.tau. proteins exhibit the antiviral and antiproliferative properties characteristic of type I interferons. An advantage of the invention is that IFN-.tau. has essentially no cytotoxic effects on treated cells as does, for example, IFN-.alpha..
    Type: Grant
    Filed: May 31, 1995
    Date of Patent: August 24, 1999
    Assignee: University of Florida
    Inventors: Fuller Warren Bazer, Howard Marcellus Johnson, Carol Hanlon Pontzer, Troy Lee Ott, Gino Van Heeke
  • Soluble 7-transmembrane domain G-protein-coupled receptor compositions and methods
    Patent number: 5925549
    Abstract: Chimeric polypeptides containing the N-terminal amino acid sequence of a glycoprotein hormone receptor polypeptide and a membrane anchor polypeptide, with a protease recognition site between the two, are disclosed. Also disclosed are nucleic acids encoding such polypeptides, expression vectors containing such nucleic acids and methods of producing such recombinant chimeric polypeptides, as well as uses thereof. The chimeric polypeptides are particularly useful for the production of soluble glycoprotein hormone receptor polypeptides.
    Type: Grant
    Filed: April 14, 1997
    Date of Patent: July 20, 1999
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Aaron J. W. Hsueh, Brian K. Kobilka, Masataka Kudo