Patents Represented by Attorney Johanna M. Corbin

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  • Peptide antiangiogenic drugs
    Patent number: 6774211
    Abstract: Peptides having the formula: A0-A1-A2-A3-A4-A5-A6-A7-A8-A9-A10 wherein A0 is selected from hydrogen or an acyl group; A10 is a hydroxyl group or an amino acid amide; and A1, A2, A3, A4, A5, A6, A7, A8, and A9 are amino acyl residues as defined herein.
    Type: Grant
    Filed: April 11, 2001
    Date of Patent: August 10, 2004
    Assignee: Abbott Laboratories
    Inventors: Jack Henkin, Fortuna Haviv, Michael F. Bradley, Douglas M. Kalvin, Andrew J. Schneider
  • Peptides having antiangiogenic activity
    Patent number: 6753408
    Abstract: Peptides of formula (I) Xaa1-Xaa2-Xaa3-Xaa4-Xaa5-Xaa6-Xaa7-Xaa8-Xaa9-Xaa10-Xaa11  (I), are useful for inhibiting angiogenesis. Also disclosed are angiogenesis-inhibiting compositions and methods of inhibiting angiogenesis in a mammal.
    Type: Grant
    Filed: November 22, 2000
    Date of Patent: June 22, 2004
    Inventors: Fortuna Haviv, Jack Henkin, Michael F. Bradley, Douglas M. Kalvin, Andrew J. Schneider
  • Fluorenes and anthracenes that inhibit P2X3 and P2X2/3 containing receptors
    Patent number: 6693136
    Abstract: Compounds of formula (I) are novel P2X3 and P2X2/P2X3 containing receptor antagonists and are useful in treating pain, urinary incontinence, and bladder overactivity.
    Type: Grant
    Filed: July 26, 2002
    Date of Patent: February 17, 2004
    Assignee: Abbott Laboratories
    Inventors: Chih-Hung Lee, Meiqun Jiang, Richard A. Perner, Arthur Gomtsyan, Erol K. Bayburt, Guo Zhu Zheng
  • Concentrated spent fermentation beer or saccharopolyspora erythraea activated by an enzyme mixture as a nutritional feed supplement
    Patent number: 6616953
    Abstract: A feed additive composition which contains enzyme-treated, concentrated spent fermentation beer of Saccharopolyspora erythraea; a method for making a feed additive containing enzyme-treated concentrated spent fermentation beer of Saccharopolyspora erythraea; a process for improving the nutritive value of spent fermentation beer of Saccharopolyspora erythraea by enzymatic treatment; a method for feeding livestock with a feed containing an enzyme-treated, concentrated spent fermentation beer of Saccharopolyspora erythraea additive and a process for improving poultry feed conversion, breast meat yield and intestinal strength by feeding a feed containing an enzyme-treated, concentrated spent fermentation beer of Saccharopolyspora erythraea additive are disclosed. Preferably, the spent fermentation beer of Saccharopolyspora erythraea is treated with a cellulase and at least one glycosidase, and then concentrated.
    Type: Grant
    Filed: December 21, 2001
    Date of Patent: September 9, 2003
    Assignee: Abbott Laboratories
    Inventors: Daniel J. Fidler, Jay Sanford Lampel, Daniel B. Weyant