Abstract: The invention relates to medicine and pharmacology, and represents a pharmaceutical composition for the treatment of bone resorption of various etiology comprising, as the biologically active ingredient, liposomes with biphosphonates in gel dosage form suitable for transdermal delivery of biphosphonates and effective local therapy. Using this composition, methods for the prevention and treatment of osteoporosis, Paget's disease, patoplogical fractures associated with oncological diseases, and some other pathological processes associated with bone resorption and reparation are proposed.
Type:
Grant
Filed:
March 18, 2008
Date of Patent:
December 4, 2012
Inventors:
Aleksander Vladimirovich Dikovskiy, Boris Anatolievich Rudoy, Oleg Valentinovich Dorozhko