Patents Represented by Attorney John Blasdale

Find this attorney in the Justia Lawyer Directory

  • Piperidine derivatives as neurokinin antagonists
    Patent number: 5654316
    Abstract: The invention relates to compounds of the formula ##STR1## wherein X, i, j, n, n', A, A', R.sub.2, R.sub.3, and U are as described herein. The compounds of the invention are NK.sub.1 or NK.sub.2 or NK.sub.3 receptor antagonists and as such are useful in the treatment of diseases such as asthma.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: August 5, 1997
    Assignee: Schering Corporation
    Inventors: Nicholas I. Carruthers, Cheryl A. Alaimo
  • Process for the preparation of triazolones
    Patent number: 5625064
    Abstract: Described is a process for preparing triazolone compounds of the formula ##STR1## comprising heating a mixture of a compound of the formula ##STR2## and a hydrazine derivative of the formula R.sup.5 --NH--NH--CHO, R.sup.5 --NH--NH--C(O)OC(CH.sub.3).sub.3 or R.sup.5 --NH--NH--C(O)OCH.sub.2 C.sub.6 H.sub.5, optionally in the presence of an added base.
    Type: Grant
    Filed: June 2, 1995
    Date of Patent: April 29, 1997
    Assignee: Schering Corporation
    Inventors: David R. Andrews, Dinesh Gala, Jacques Gosteli, Frank Guenter, William Leong, Ingrid Mergelsberg, Anantha Sudhakar