Patents Represented by Attorney, Agent or Law Firm John Christopher James
  • Patent number: 6827711
    Abstract: The invention provides a nested tubing cannula which comprises outer and inner elongate tubular members, both having a proximal end, a distal end, and a lumen therebetween. The inner tubular member is sealed at its distal end and is nested substantially coaxially within the lumen of the outer tubular member, so that the gap between the inner and the outer tubular member defines a second lumen whereas the first lumen is the lumen of the inner tubular member. A tubular sleeve is disposed coaxially between the inner and outer tubular members. A balloon is mounted on a distal region of the outer tubular member and is in communication with the first lumen. The cannula further comprises a port proximal or distal the balloon occluder and is in communication with the second lumen. Methods for making the devices herein are disclosed.
    Type: Grant
    Filed: November 29, 2001
    Date of Patent: December 7, 2004
    Assignee: Edwards Lifesciences Corporation
    Inventor: Gary Sunseri
  • Patent number: 6827494
    Abstract: A hydrodynamic thrust bearing of this invention comprises a body having a load-bearing surface comprising an oil supply channel and an oil return channel positioned along respective inside and outside body diameters. A number of thrust pads are positioned along the surface that each include an oil supply groove, positioned adjacent a leading edge/upstream portion of each thrust pad and extending radially a distance from the oil supply channel, and an oil return groove, positioned adjacent a trailing edge/downstream portion of each thrust pad and extending radially a distance from the oil return channel. The oil supply grooves are separate from the oil return grooves, and the thrust pads each comprise a series arrangement of three differently configured land or pad sections. Configured in this manner, oil is provided onto the series of land sections by the oil supply groove and is collected after passing over the series of land sections by the separate oil collection groove.
    Type: Grant
    Filed: October 23, 2002
    Date of Patent: December 7, 2004
    Assignee: Honeywell International, Inc.
    Inventor: Scott Grover Aguilar
  • Patent number: 6811756
    Abstract: An exhaust gas cooler for reducing the temperature of exhaust gases from internal combustion engines, comprising an external tube extending between two tube plates or end walls and defining a coolant chamber, coolant inlet and outlet means communicating with the coolant chamber, and a plurality of internal tubes extending between the end walls and arranged to carry the exhaust gas through the coolant chamber. The external tube has a cross-sectional shape which has a height (H) in the major axis which is greater than its width (W) in the minor axis perpendicular to the major axis, preferably oval, or comprising two semi-circles connected by common straight line tangents parallel to the major axis. Such a cross-sectional shape means that the exterior tube has a planar face which simplifies the fitting of mounting brackets and placement with an engine compartment.
    Type: Grant
    Filed: April 30, 2001
    Date of Patent: November 2, 2004
    Assignee: Honeywell International INC
    Inventor: George Atkinson
  • Patent number: 6807955
    Abstract: An exhaust gas recirculation cooler (1) with a coolant chamber (14), a bypass tube (50) and means (70) to selectively direct exhaust gas through the coolant chamber (14) or bypass tube (50). The bypass tube (50) may be used to direct hot exhaust gases to the engine under low engine temperature/load operating conditions and during start up of the engine; the coolant chamber (14) may be used to cool very hot gases under high engine temperature/load conditions and direct the cooled gas to the engine. The bypass tube (50) is integrally formed with the coolant chamber, reducing space required for the cooler and making for easier installation.
    Type: Grant
    Filed: January 6, 2003
    Date of Patent: October 26, 2004
    Assignee: Honeywell International, Inc.
    Inventors: Stewart William Leedham, Matthew Thomas Graham Stonehouse
  • Patent number: 6802860
    Abstract: An assembly for holding a substantially flexible suture guide of predetermined length in a substantially taut position used to achieve a suture line having a dimension equal to the length of the suture guide, such as the circumference about a heart valve annulus. The assembly includes a rigid suture guide holder having a surface against which the length of suture guide is releasably positioned. The guide holder can have a shape or geometry, such as a circumference or circumferential segment, equivalent to the shape or geometry of the intended suture line. The shape of the guide holder can therefore be selected to hold the suture guide in the shape most advantageous to placing the desired suture line.
    Type: Grant
    Filed: April 8, 2003
    Date of Patent: October 12, 2004
    Assignee: Edwards Lifesciences Corporation
    Inventors: Delos M. Cosgrove, Than Nguyen
  • Patent number: 6790219
    Abstract: An endoluminal device having an elongate tubular member and a filter slideably received within a lumen of the tubular member. An obturator tip is carried by the filter and shaped to rest against the distal end of the elongate tubular member when the filter is within the lumen of the tubular member. Methods of using the obturator and the introducer for introducing the filter into a vessel, such as an aorta, are also disclosed.
    Type: Grant
    Filed: November 6, 2001
    Date of Patent: September 14, 2004
    Assignee: Edwards Lifesciences Corporation
    Inventor: Richard O. Murphy
  • Patent number: 6767362
    Abstract: Expandable heart valves for minimally invasive valve replacement surgeries are disclosed. In a first embodiment, an expandable pre-assembled heart valve includes a plastically-expandable annular base having plurality of upstanding commissure posts. A tubular flexible member including a prosthetic section and a fabric section is provided, with the prosthetic section being connected to the commissure posts and defining leaflets therebetween, and the fabric section being attached to the annular base. In a second embodiment, an expandable heart valve includes an annular tissue-engaging base and a subassembly having an elastic wireform and a plurality of leaflets connected thereto. The annular base and subassembly are separately stored and connected just prior to delivery to the host annulus. Preferably, the leaflet subassembly is stored in its relaxed configuration to avoid deformation of the leaflets. The expandable heart valves may be implanted using a balloon catheter.
    Type: Grant
    Filed: June 28, 2002
    Date of Patent: July 27, 2004
    Assignee: Edwards Lifesciences Corporation
    Inventor: Stefan Schreck
  • Patent number: 6767323
    Abstract: The invention provides devices and methods for endoscopically cannulating the aorta, right atrium, and other body tissues to establish cardiopulmonary bypass for minimally invasive coronary artery bypass grafting surgery, and for other surgeries. After inserting the suction support through a minimal access port, the suction support having an arcuate member with suction ports provides countertraction to the aorta by creating a vacuum seal between its suction ports and the aorta, therefore facilitating aortic incision and cannulation. In one embodiment, the suction support allows aorta stabilization, incision, and insertion with an introducer to be achieved sequentially. Methods for using the devices herein are also disclosed.
    Type: Grant
    Filed: May 24, 2001
    Date of Patent: July 27, 2004
    Assignee: Edwards Lifesciences Corporation
    Inventor: Lorraine Mangosong Martinez
  • Patent number: 6749630
    Abstract: An annuloplasty ring having a three-dimensional discontinuous form generally arranged about an axis with two free ends that are axially offset. The ring is particularly suited for repair of the tricuspid valve, and more closely conforms to the annulus shape. The ring is more flexible in bending about radially extending axes than about the central axis. A deliver template having a mounting ring with about the same shape as the ring facilitates implant, and may be releasably attached to a delivery handle. The deliver template may include a plurality of cutting guides for releasably attaching the annuloplasty ring thereto while presenting maximum outer surface area of the ring. The template may have an outwardly-facing groove to receive and retain the ring.
    Type: Grant
    Filed: August 28, 2001
    Date of Patent: June 15, 2004
    Assignee: Edwards Lifesciences Corporation
    Inventors: Patrick M. McCarthy, Richard S. Rhee, Stefan G. Schreck
  • Patent number: 6743246
    Abstract: Method and apparatus for deploying a medical device in a vessel. The apparatus includes a cannula and a medical device, for example a blood filter. The cannula has a lumen that extends from a proximal end to a distal end, and a port on the outer surface of the cannula. The port has a passage extending distally. In use, the distal end of the cannula is inserted into a vessel. The medical device is inserted into the port. The medical device is advanced through the passage into the blood vessel. The medical device is deployed within the vessel. Finally, the medical device is removed from the vessel.
    Type: Grant
    Filed: March 7, 2001
    Date of Patent: June 1, 2004
    Assignee: Edwards Lifesciences Corporation
    Inventor: Tracy D. Maahs
  • Patent number: 6736845
    Abstract: A holder for a highly flexible tissue-type heart valve is disclosed that maintains an implant shape to the valve. The holder may have cusp and commissure contacting supports, and may be attached at all six such supports, or only three. The holder may be flexible to permit inward flexing of the heart valve during implant for greater visibility when implanting using a running suture method. The holder may be formed of flexible wires such as Nitinol, and shaped to resist excessive axial and torsional deformation of the valve. A short handle connector suitable for manual grasping may be attached and stored with the valve, with the handle connector having a coupling for receiving a longer delivery handle. A two stage holder may be utilized to accommodate different implant methods.
    Type: Grant
    Filed: May 3, 2001
    Date of Patent: May 18, 2004
    Assignee: Edwards Lifesciences Corporation
    Inventors: Salvador Marquez, Claudio Argento, Richard S. Rhee
  • Patent number: 6732739
    Abstract: A minimally invasive approach for surgery on portions of the heart and great vessels. A parasternal incision is made extending across a predetermined number of costal cartilages, e.g., a right parasternal incision extending from the lower edge of the second costal cartilage to the superior edge of the fifth costal cartilage. One or more costal cartilages, e.g., the third and fourth, are then excised to provide access to the portion of the heart or great vessels of interest, for example between a point approximately three centimeters above supra annular ridge and the mid ventricular cavity, and a desired procedure completed.
    Type: Grant
    Filed: February 10, 2003
    Date of Patent: May 11, 2004
    Assignee: The Cleveland Clinic Foundation
    Inventor: Delos M. Cosgrove
  • Patent number: 6733525
    Abstract: Expandable heart valves for minimally invasive valve replacement surgeries are disclosed. The valves are rolled into a first, contracted configuration for minimally invasive delivery and then unrolled or unfurled at the implantation site. One- and two-piece stents may be used in conjunction with a plurality of flexible leaflet-forming membranes. The one-piece stents may include an annulus anchoring section, a sinus section with the membranes attached over sinus apertures, and a rigid outflow section. The two-piece stent may include a primary stent to provide a tubular base at the annulus, and a secondary stent having the membranes that couples within the primary stent. Lockout tabs to secure the stents in their expanded shapes are provided. Also, alignment structure may be provided to ensure concentric unfurling. Anchoring barbs at the stent edges or in the stent body secure the valve within the annulus. Methods of implantation are also provided.
    Type: Grant
    Filed: March 23, 2001
    Date of Patent: May 11, 2004
    Assignee: Edwards Lifesciences Corporation
    Inventors: Jibin Yang, Matthew L. Pease, Brandon G. Walsh
  • Patent number: 6730313
    Abstract: The invention provides methods for treating injuries to one or more internal structures of a subject by administering a drug delivery vehicle to an external surface of the injured structure. The drug delivery vehicle substantially adheres to the site of administration and provides for the release of a bioactive agent that reduces or prevents further injury to the internal structure by disease processes, such as hyperplasia.
    Type: Grant
    Filed: January 25, 2001
    Date of Patent: May 4, 2004
    Assignee: Edwards Lifesciences Corporation
    Inventors: Michael N. Helmus, Crystal M. Cunanan, Patrice Tremble
  • Patent number: 6726716
    Abstract: The resilient self molding annuloplasty ring which may be enlarged prior to implantation to facilitate implantation within a dilated or otherwise incompetent valve annulus having sufficient contractive force to render a valve competent. The self molding annuloplasty ring of the invention may further comprise integral attachment devices to aid in the implantation process. The invention further discloses an illustrative method of implantation.
    Type: Grant
    Filed: August 24, 2001
    Date of Patent: April 27, 2004
    Assignee: Edwards Lifesciences Corporation
    Inventor: Salvador Marquez
  • Patent number: 6726717
    Abstract: The present invention refers to an annular prosthesis for mitral valve. In one of its embodiments the annular prosthesis for mitral valve is made up of a posterior half-ring and an anterior half-ring coupled to each other on a first transverse plane which defines a maximum width section of the prosthesis, characterised in that the ratio between the distance between said anterior half-ring and said posterior half-ring, as measured along a second plane, perpendicular to said first plane and equidistant to said couplings, and said maximum width of the prosthesis is lower than 3/4.
    Type: Grant
    Filed: May 15, 2002
    Date of Patent: April 27, 2004
    Assignee: Edwards Lifesciences Corporation
    Inventors: Ottavio Alfieri, Francesco Maisano, Alberto Redaelli
  • Patent number: 6723085
    Abstract: A filter comprising a porous material is arranged in a generally conical shape having an expandable base and a vertex. An elongate member having a proximal end and a distal end is attached to the expandable base of the porous material at a first circumferential location of the expandable base and extends perpendicularly from a central axis of the filter. An aspiration tube, for removing embolic material under vacuum, communicates with an area at the first circumferential location of the expandable base. Methods of using the filter and occluding devices for protecting a patient from embolization during cardiovascular procedures are described.
    Type: Grant
    Filed: June 17, 2002
    Date of Patent: April 20, 2004
    Assignee: Edwards Lifesciences Corporation
    Inventors: Yue-Teh Jang, Richard O. Murphy, Roman Turovskiy
  • Patent number: 6706033
    Abstract: Modular systems comprising a cannula and at least one access port adjacent to a distal end of the cannula provide insertion of one or more therapeutic or diagnostic devices into a vessel or cardiac tissue through a single incision site. Other embodiments include a vessel introducer or multi-port introducer. The devices can be operated in combination or independently. The systems can be employed to provide multiple therapies, including blood perfusion, filtration, aspiration, vessel occlusion, atherectomy, and endoscopic devices. Methods of using the system for vessel cannulation are also disclosed herein.
    Type: Grant
    Filed: August 2, 1999
    Date of Patent: March 16, 2004
    Assignee: Edwards Lifesciences Corporation
    Inventors: Lorraine Mangosong Martinez, Jobert Balceta, Kevin Hahnen, Bruce Addis, Timothy J. Wood, Roman Turovskiy, Richard O. Murphy, Tracy D. Maahs
  • Patent number: 6702852
    Abstract: An improved holder, system and method for implanting a tissue-type prosthetic heart mitral valve that constricts the commissure posts of the valve and allows the user to detach the handle of the holder prior to withdrawing the holder itself. The ability to remove the handle allows a surgeon greater access to suturing the prosthetic valve to the mitral annulus. The holder may include two relatively movable plates, one of which attaches to the valve sewing on the inflow end of the valve ring and the other which attaches via sutures to the valve commissures on the outflow end. Separation of the plates places the sutures in tension and constricts the commissures. An adjusting member or adapter is interposed between the handle and holder to enable separation of the two plates and removal of the handle. The adjusting member or adapter may be packaged with the valve and holder combination, or may be sold as a separate unit, possibly with the handle, so that prior art holders can be retrofit.
    Type: Grant
    Filed: April 23, 2002
    Date of Patent: March 9, 2004
    Assignee: Edwards Lifesciences Corporation
    Inventors: Robert Stobie, Jerry L. Jackman, Cuong Ton-That, C. Roger Ekholm, Steve Newborg
  • Patent number: 6692512
    Abstract: A percutaneous filtration catheter used to entrap emboli from a patient's aorta and heart during cardiac surgery. The catheter has an elongate member, a proximal end, and a distal end. A balloon occluder is mounted on the distal end of the elongate member and an expandable filter is mounted on the elongate member distal the balloon occluder. Methods for using the devices are also disclosed herein.
    Type: Grant
    Filed: June 25, 2001
    Date of Patent: February 17, 2004
    Assignee: Edwards Lifesciences Corporation
    Inventor: Yue-Teh Jang