Patents Represented by Attorney John D. Fish & Richardson Conway
  • Patent number: 6004928
    Abstract: The present invention relates to a method of decreasing body weight in a patient. The method includes the step of administering a therapeutically effective amount of a type-5 selective somatostatin agonist to the patient.
    Type: Grant
    Filed: May 13, 1998
    Date of Patent: December 21, 1999
    Assignee: Biomeasure, Incorporated
    Inventors: Michael Anthony Cawthorne, Yong-Ling Liu, Matthew V. Sennitt
  • Patent number: 6001801
    Abstract: A cyclic peptide analog of somatostatin wherein a disulfide bond links the N-terminus residue and the C-terminus residue.
    Type: Grant
    Filed: January 13, 1998
    Date of Patent: December 14, 1999
    Assignees: Biomeasure, Inc., Tulane Univ. Medical Ctr.
    Inventors: David H. Coy, John E. Taylor
  • Patent number: 5969095
    Abstract: Peptide variants of fragment (1-34) of parathyroid hormone, in which at least one of the amino acid residues at positions 7, 11, 23, 24, 27, 28, and 31 is cyclohexylalanine, or at least one of the amino acid residues at positions 3, 16, 17, 18, 19, and 34 is .alpha.-aminoisobutyric acid; or, alternatively, at least the amino acid residue at position 1 is .alpha.,.beta.-diaminopropionic acid, the amino acid residue at position 27 is homoarginine, or the amino acid residue at position 31 is norleucine.
    Type: Grant
    Filed: January 7, 1997
    Date of Patent: October 19, 1999
    Assignee: Biomeasure, Inc.
    Inventor: Zheng Xin Dong
  • Patent number: 5968903
    Abstract: The present invention is directed to a method of using somatostatin or a somatostatin agonist to inhibit the proliferation of Helicobacter pylori (H. pylori), which comprises administering to a patient in need thereof an effective amount of said somatostatin or somatostatin agonist. Preferably, a somatostatin sub-type receptor 2 (SSTR-2) selective somatostatin agonist is administered in a method of this invention. The inhibition of H. pylori proliferation is useful in treating various gastroduodenal diseases such as peptic ulcers, gastric cancer and gastric lymphoma.
    Type: Grant
    Filed: May 7, 1998
    Date of Patent: October 19, 1999
    Assignee: Biomeasure, Incorporated
    Inventors: Hiroshi Kaneko, Terunori Mitsuma, Koichi Yamashita, Barry Morgan
  • Patent number: 5863985
    Abstract: Disclosed is a sustained release pharmaceutical composition. The composition includes a polyester containing a free COOH group ionically conjugated with a bioactive polypeptide comprising at least one effective ionogenic amine, wherein at least 50% by weight of the polypeptide present in the composition is ionically conjugated to the polyester.
    Type: Grant
    Filed: June 2, 1997
    Date of Patent: January 26, 1999
    Assignee: Kinerton Limited
    Inventors: Shalaby W. Shalaby, Steven A. Jackson, Jacques-Pierre Moreau
  • Patent number: 5814463
    Abstract: Pure nucleic acids encoding novel receptors for bombesin-like peptides, the novel receptors themselves, and their antibodies. Also disclosed is a method of screening for a compound capable of interacting with any of these novel receptors.
    Type: Grant
    Filed: August 12, 1997
    Date of Patent: September 29, 1998
    Assignee: The Medical Research Foundation of Oregon
    Inventors: Eliot R. Spindel, Srinivasa Nagalla, Brenda Barry
  • Patent number: 5747456
    Abstract: A method of promoting bone formation in a human patient, which includes the step of administering continuously to the patient parathyroid hormone or its agonist for a period of at least one month at a dosage between 10 and 400 units/24 hrs. Also disclosed are novel parathyroid hormone agonists.
    Type: Grant
    Filed: September 30, 1996
    Date of Patent: May 5, 1998
    Assignee: Beth Israel Deaconess Medical Center
    Inventors: Michael Chorev, Michael Rosenblatt