Abstract: The frequency shift of reflected laser beam from a target is transformed o an angular measurement which is proportional to the velocity of the target relative to the measurement platform. The system uses the refraction angle of the reflected beam from a movable optical grating to produce the angular measurement.

Abstract: A sensitive and specific radioimmunoassay is developed for L-hyoscyamine ulting from atropine administration with which a concentration as low as 25 pg/ml using 0.1 ml of sample can be measured without the need for extraction. Specificity studies indicate that an antibody according to this invention has high specific recognition of L-hyoscyamine with only about 37% cross reaction with the D-hyoscyamine enantiomer of atropine. The antibody is produced from an immunogen having conjugated at least 42 and preferably 45 L-hyoscyamine-p-aminobenzoic acid haptenic molecules per molecule of bovine serum albumin. An antibody according to this invention can be used with a dilution titer as high as 1:2000.

Abstract: This invention relates to a novel method for separating and measuring the amount of polar compounds, such as pyridostigmine, acetylcholine, neostigmine, and edrophonium, and their metabolites in aqueous solutions. The method is used to determine the urinary excretion and plasma levels of polar compounds administered to animals.

Abstract: This invention involves amine-carbamoylborane compounds of the formulaR.sub.1 R.sub.2 NH.BH.sub.2 C(O)NHR.sub.3wherein R.sub.1 and R.sub.2 are hydrogen or certain alkyl moieties and R..3 is an alkyl. A process for their preparation involving an amine displacement reaction is also described. A method of use and pharmaceutical compositions containing the subject compounds are also described.

Abstract: A typical embodiment of the invention enables a surgeon to occupy only one and in manipulating a suture needle. The instrument thumb handle has, on one end, a freely rotatable short roller. The ring finger handle, moreover, has a long roller that is journalled within that handle. One end of the long roller bears against the short roller to form a nip that engages the suture needle. The other end of the long roller terminates near the ring finger handle grip to enable the surgeon to rotate the long roller with another finger of the same hand and thereby draw the needle through the nip, repositioning the needle for another stitch.

Abstract: A novel material consisting of a combination of a proteolipid and biodegradable, biocompatible copolymer has been developed for improving and accelerating the healing of osseous tissue. The proteolipid was prepared by combining muco-peptide-N-acetyl-muramoylhydrolase with phosphatidyl inositol, 4,5-diphosphate and the copolymer consists essentially of a 50:50 poly(L)(-)lactide co-glycolide.

Abstract: A method and apparatus are provided for data compression in a digital facile document transmission system. In accordance with the method, only alternate scan lines are transmitted, i.e., every other line is deleted in transmission, and at the receiver, the missing scan lines are interpolated from the transmitted data. This compression technique provides a fixed compression ratio of 2 to 1 regardless of the complexity of the input document. The interpolation method relies on comparing, for each picture element to be interpolated, the colors of one or more pairs of adjacent picture elements of the transmitted scan lines and making a decision as to the color of the picture element to be interpolated on this basis.

Abstract: This invention is directed to a Wheatstone bridge circuit for measuring pressure in the distal esophageal sphincter (D.E.S.) as well as in other organs and bodily cavities. A flexible hollow tube having three spaced electrodes is lodged in the esophagus. The tube is partly filled with a saline solution to cover the electrodes, thereby producing two series connected, pressure sensitive resistors. The electrolytic resistors are coupled to two series connected fixed resistors to complete the bridge circuit. Electrical imbalances in the bridge circuit are measured in terms of the pressure corresponding to the pressure applied by the D.E.S.

Abstract: SSICM is a missile configuration which employs spin stabilization, nutatil motion, and impulsive thrusting, and a body mounted passive or semiactive sensor to achieve very small miss distances against a high speed moving target. SSICM does not contain an autopilot, control surfaces, a control actuation system, nor sensor stabilization gimbals. SSICM spins at a rate sufficient to provide frequency separation between body motions and inertial target motion. Its impulsive thrusters provide near instantaneous changes in lateral velocity whereas conventional missiles require a significant time delay to achieve lateral acceleration.

Abstract: Improved means for the chemotherapy of malaria have been achieved with 5-oxy-primaquine analogues having the formula: ##STR1## wherein R.sub.4 represents hydrogen or a methyl grouping, and R represents an alkyl group containing 3 to 12 carbon atoms and pharmaceutically acceptable salts thereof, wherein the salt-forming acid may be organic or inorganic in nature. These primaquine-related compounds afford improvement in the chemotherapy of malaria by exerting plasmodicidal action on malaria parasites which may be present in either the blood, formed tissues, or blood and formed tissues of the mammalian host. Such broad and practical spectrum of effectiveness distinguishes the said primaquine analogues, which may be administered parenterally or perorally to infected animals.

Abstract: This rotationally symmetric optical sensor consists of six lens elements e selectively of the alkali halide materials KBr, C I, and KI. It has a wide field-of-view coverage of 60 degrees and operates in the middle infrared through the far infrared bands and extends well into the extreme infrared band. The combination of optical materials selected to be used effectively corrects the chromatic and monochromatic aberrations of the sensor.

Abstract: The guidance scheme utilizes wide beam width semi-active RF sensors, a prsion roll altitude reference, and a controlled grade pitch, yaw and roll rate gyros to deliver high quality homing guidance information to a spin stabilized controlled missile. A filtering system is utilized to eliminate errors caused by body roll signals generated due to the spin of the missiles. The nutational motion is used to calibrate the sensors. Impulsive maneuvers are utilized to intercept incoming ballistic targets.

Abstract: This disclosure concerns a communications network information system, and ovides apparatus and a method for efficiently providing survivable communications capability to every surviving node in the communications network from every other surviving node. The types of information provided can include high priority message between users of the communications system, or perhaps of even greater importance, very frequently updated status information about the communications network nodes and their interconnecting links for use in optimally utilizing the surviving resources of a heavily damaged network. With this capability every surviving node in the network will be automatically and efficiently provided with the status of every node and interconnecting link.

Abstract: Disclosed is a method of microwave drying of ammonium perchlorate grinding pheres. A preferred embodiment of the method employs a tunnel oven in combination with a microwave generator having an appropriate power supply. The tunnel oven receives microwave energy through transmission ducts in communication with a channeling device to distribute microwave energy over the grinding spheres to be dried. A preheated air supply facilitates moisture removal from the tunnel oven after the moisture adhered or occluded to the grinding spheres' surfaces is evaporated from the grinding spheres as a result of molecular vibrations of the water molecules after they absorb the microwave energy. A predetermined microwave frequency range and a predetermined drying time are employed to more efficiently remove adhered or occluded moisture from carbide grinding spheres as compared to conventional convection drying.

Abstract: Ethanol is recovered from fermentation products by a countercurrent extraction process which employs diethyl ether as the extraction solvent to form a diethyl ether-ethanol mixture. The ethanol is salted out by adding calcium chloride to the mixture, and the diethyl ether layer is separated and recycled. The calcium chloride in ethanol solution is removed by adding sodium carbonate to form the solids calcium carbonate and sodium chloride which are removed by filtration. The ethanol is recovered as the filtrate.

Abstract: A typical embodiment of the invention provides a means for protecting delte instruments from damage. A flexible membrane separates two chambers in which, during ordinary operation, the fluid pressures are the same. One of the two chambers also serves as a fluid conduit in the system. Pressure loss in the system causes the higher pressure chamber to flex the membrane which closes a port in the fluid conduit chamber, thereby preventing further system pressure loss and consequent equipment damage. The membrane, moreover, can have a small bleed to permit gradual, dampened fluid pressure release.

Abstract: An apparatus for measuring the strength of a bond between a lamina and its ubstrate, or the like is shown and described. Air, or some other fluid under pressure, causes a gasket to protrude from a piston to seal the atmosphere from a chamber within the piston and the adjacent exposed lamina surface. The fluid also pressurizes this chamber to pull a loading fixture and a portion of the lamina attached thereto away from the substrate. The force required to pull the lamina from the substrate is equal to the strength of the bond.

Abstract: A tomographic marking device is disposed in an electron microscope between a goniometer stage for holding a specimen and a fluorescent screen for displaying a magnified image of the specimen. The device comprises an externally geared, ring wheel, having a pair of spaced-apart, colinearly disposed pins fixed to the inner periphery of the wheel and defining a straight line parallel to both the screen and the tilt axis of rotation of the goniometer stage. Because the magnetic lenses of the microscope rotate the magnified image on the screen, means are provided to rotate the wheel and to indicate the position of angular rotation of the tilt axis of the goniometer stage located on the screen relative to the actual tilt axis of the goniometer stage.

Abstract: A method for the production of stroma-free, non-heme protein-free hemoglo by use of zinc ion to promote precipitation of a zinc ion-bound insoluble hemoglobin complex, followed by membrane ultrafiltration of the zinc-hemoglobin complex from the filtrate fluid medium, preferably with a saline dialyzate.

Abstract: Unconfined detonation by a single-event process is achieved by simultaneous ispersion of both fuel and the initiating chemical catalyst into the atmosphere. The fuel is selected from a volatile liquid (lower molecular weight, alkanes, epoxyalkanes, etc.), aluminum, boron, etc. or mixtures thereof. The initiating chemical catalyst is selected from n-hexylcarborane, carboranylmethyl propionate, ferrocene, n-butylferrocene etc. The fuel and initiating chemical catalyst are dispersed simultaneously to form a cloud after the catalyst is premixed with the fuel and housed in a container prior to dispersion. The dispersed catalyst catalyzes the reaction between fuel and atmosphere oxygen to produce the explosive oxidation of the fuel-air mixture.Additional enhancers for detonability such as a bis(difluoroamino) compound (TVOPA) and/or ultrafinely-ground ammonium perchlorate are included in the fuel-catalyst mixture when the unconfined detonation is to be achieved in an oxygen-deficient atmosphere.