Patents Represented by Attorney John Kappos

Find this attorney in the Justia Lawyer Directory

  • Antibiotic 107891, its factors A1 and A2, pharmaceutically acceptable salts and compositions, and use thereof
    Patent number: 7351687
    Abstract: The invention relates to an antibiotic substance of microbial origin, arbitrarily denominated antibiotic 107891 which is produced by fermentation of Microbispora sp. ATCC PTA-5024, the pharmaceutically acceptable salts and compositions thereof, and their use as an antibacterial agent having inhibitory activity versus susceptible microbes. Antibiotic 107891, which is a complex comprising two Factors, denominated Factors A1 and A2, has a peptide structure containing lanthionine and methyllanthionine as constituents which are typical characteristics of the antibiotics of the lantibiotics group. Antibiotic 107891 and its Factors A1 and A2 show a good antibacterial activity against Gram-positive bacteria including methicillin resistant and vancomycin resistant strains, and is active also against some Gram-negative bacteria such as M. catharralis, Neisseria species and H. influenzae and Mycobacteria.
    Type: Grant
    Filed: January 26, 2005
    Date of Patent: April 1, 2008
    Assignee: Vicuron Pharmaceuticals, Inc.
    Inventors: Ameriga Lazzarini, Luciano Gastaldo, Gianpaolo Candiani, Ismaela Ciciliato, Daniele Losi, Flavia Marinelli, Enrico Selva, Franco Parenti
  • Antibiotic 107891, its factors A1 and A2, pharmaceutically acceptable salts and compositions, and use thereof
    Patent number: 7319088
    Abstract: The invention relates to an antibiotic substance of microbial origin, arbitrarily denominated antibiotic 107891 which is produced by fermentation of Microbispora sp. ATCC PTA-5024, the pharmaceutically acceptable salts and compositions thereof, and their use as an antibacterial agent having inhibitory activity versus susceptible microbes. Antibiotic 107891, which is a complex comprising two Factors, denominated Factors A1 and A2, has a peptide structure containing lanthionine and methyllanthionine as constituents which are typical characteristics of the antibiotics of the lantibiotics group. Antibiotic 107891 and its Factors A1 and A2 show a good antibacterial activity against Gram-positive bacteria including methicillin resistant and vancomycin resistant strains, and is active also against some Gram-negative bacteria such as M. catharralis, Neisseria species and H. influenzae and Mycobacteria.
    Type: Grant
    Filed: January 12, 2005
    Date of Patent: January 15, 2008
    Assignee: Vicuron Pharmaceuticals Inc.
    Inventors: Ameriga Lazzarini, Luciano Gastaldo, Gianpaolo Candiani, Ismaela Ciciliato, Daniele Losi, Flavia Marinelli, Enrico Selva, Franco Parenti