Patents Represented by Attorney John M. Sanders
  • Patent number: 5316943
    Abstract: Recombinant cells and an improved method utilizing them is disclosed for the preparation of an optically pure, L-amino acid from its D and D,L isomer forms. The process utilizes cell cultures that possess high aminotransferase activity that exhibits moderate selectivity in the conversion of D and L amino acids to their respective 2-keto acids as well as absolute stereospecificity in the conversion of the 2-keto acids to the L isomer alone.
    Type: Grant
    Filed: June 19, 1989
    Date of Patent: May 31, 1994
    Inventors: Gene E. Kidman, Larry E. Robinson, Mark P. Scollar, Ian G. Fotheringham
  • Patent number: 5266717
    Abstract: N-(sulfomethyl)-N'-arylureas inhibit or suppress bitter and sweet tastes when mixed with sweet and/or bitter tasting compositions, such as foods, beverages and pharmaceutical preparations.
    Type: Grant
    Filed: October 17, 1990
    Date of Patent: November 30, 1993
    Inventors: Glenn Roy, Chris Culberson, George Muller, Srinivasan Nagarajan
  • Patent number: 5229158
    Abstract: Macrocolloids of polyhydroxyalkanoates are used as fat substitutes. Polyhydroxybutyrate is the preferred homopolymer. The polymeric particles can have a particle size of from 0.1-10 microns.
    Type: Grant
    Filed: November 21, 1990
    Date of Patent: July 20, 1993
    Inventor: Manssur Yalpani
  • Patent number: 5225227
    Abstract: Polyhydroxyalkanoates are combined with fat soluble flavors to provide a flavor delivery system for low-fat and no-fat foods. The polyhydroxyalkanoates preferably have a porous structure.
    Type: Grant
    Filed: November 21, 1990
    Date of Patent: July 6, 1993
    Inventor: Manssur Yalpani
  • Patent number: 5143741
    Abstract: Substantially non-aggregated casein micelles are employed as a fat substitute in food products. The concentrated casein micelles can replace all or a portion of the fat or cream in food products such as frozen dairy desserts, icings, puddings, whipped toppings, fortified skim milk, dips, spreads and sauces.
    Type: Grant
    Filed: October 30, 1991
    Date of Patent: September 1, 1992
    Inventors: Joseph S. Podolski, Maher Habib
  • Patent number: 5112956
    Abstract: The present invention relates to a method for the removal of lipids and cholesterol from protein materials comprising the steps of (a) treating the protein with an extraction mixture comprising a lower alcohol, water and an acid, in concentrations selected to extract cholesterol and lipids from the protein, and (b) removing the extraction mixture from the protein.
    Type: Grant
    Filed: March 17, 1989
    Date of Patent: May 12, 1992
    Assignee: The NutraSweet Company
    Inventors: Pamela S. Tang, Norman S. Singer, Hsien-Hsin Chang
  • Patent number: 5053532
    Abstract: A one-pot process for the preparation of .alpha.-L-aspartyl-L-phenylalanine methyl ester hydrochloride is disclosed (.alpha.-APM(HCl)). .alpha.-APM(HCl) is an intermediate in the preparation of aspartame.
    Type: Grant
    Filed: July 3, 1990
    Date of Patent: October 1, 1991
    Assignee: The Nutra Sweet Company
    Inventors: John B. Hill, Yefim Gelman, Hugh L. Dryden, Jr., Robert Erickson, Kuang Hsu, Mark R. Johnson
  • Patent number: 5030460
    Abstract: A formulation which may be used to produce sugar-free marshmallow bits and frosted coatings is disclosed. The marshmallow bits may be used in ready-to-eat cereals. The frosted coatings may be added to a variety of food products, including cereals, cookies, confections, pastries, and sweetened snack foods. The formulation preferably includes hydrogenated starch hydrolysate, egg whites, and aspartame.
    Type: Grant
    Filed: February 23, 1990
    Date of Patent: July 9, 1991
    Assignee: The Nutra Sweet Company
    Inventor: Patricia A. Baggerly
  • Patent number: 4994490
    Abstract: N-(sulfomethyl)-N'-arylureas inhibit or suppress bitter and sweet tastes when mixed with sweet and/or bitter tasting compositions, such as foods, beverages and pharmaceutical preparations.
    Type: Grant
    Filed: April 3, 1989
    Date of Patent: February 19, 1991
    Assignee: The NutraSweet Company
    Inventors: Glenn Roy, Chris Culberson, George Muller, Srinivasan Nagarajan
  • Patent number: 4946988
    Abstract: A process for the preparation of .alpha.-L-aspartyl-L-phenylalanine methyl ester hydrochloride (.alpha.-APM(HCl)) is disclosed. .alpha.-APM(HCl) is an intermediate in the preparation of aspartame.
    Type: Grant
    Filed: July 14, 1988
    Date of Patent: August 7, 1990
    Assignee: The NutraSweet Company
    Inventors: John B. Hill, Yefim Gelman
  • Patent number: 4945172
    Abstract: N-formyl-L-aspartic anhydride is prepared using a minimum excess of formic acid. Acetic anhydride and a C.sub.3 -C.sub.6 secondary alcohol are added to the reaction mixture to consume excess formic acid. The reaction is suitable for further reactions without modification.
    Type: Grant
    Filed: November 28, 1989
    Date of Patent: July 31, 1990
    Assignee: The Nutra Sweet Company
    Inventors: John B. Hill, Hugh L. Dryden, Jr., Robert Erickson
  • Patent number: 4911946
    Abstract: A fat substitute is disclosed which comprises water-dispersable macro-colloid particles having a substantially spheroidal shape and a particle size distribution effective to impart substantially smooth organoleptic character of an oil-and-water emulsion. The particles are composed of carbohydrate material.
    Type: Grant
    Filed: June 24, 1988
    Date of Patent: March 27, 1990
    Assignee: The Nutra Sweet Company
    Inventors: Norman S. Singer, Hsien-Hsin Chang, Pamela Tang, John M. Dunn
  • Patent number: 4900740
    Abstract: N,N'-disubstituted guanidines containing a tetrazolyl or glycine moiety are provided as high potency sweetening agents.
    Type: Grant
    Filed: October 2, 1987
    Date of Patent: February 13, 1990
    Assignee: The NutraSweet Company
    Inventors: George W. Muller, Eric Walters, Grant DuBois
  • Patent number: 4892820
    Abstract: Alkylphosphate solvents are disclosed for use in an amino acid and amino acid ester enzymatic coupling process. .alpha.-Aspartylphenylalanine methyl ester and intermediates thereof are prepared enzymatically in an alkylphosphate solvent or cosolvent.
    Type: Grant
    Filed: June 10, 1987
    Date of Patent: January 9, 1990
    Assignee: The Nutrasweet Company
    Inventors: John B. Hill, Steven O. Roczniak
  • Patent number: 4447257
    Abstract: The addition of crop oil to herbicidal compositions containing pyridyloxy-phenoxy alkanoate herbicides and benzothiadiazinone herbicides inhibits the antagonism between the pyridyloxy-phenoxy alkanoate herbicides and the benzothiadiazinone herbicides.
    Type: Grant
    Filed: November 16, 1981
    Date of Patent: May 8, 1984
    Assignee: The Dow Chemical Company
    Inventor: Ben C. Gerwick, III
  • Patent number: 4419453
    Abstract: Latex agglutination test methods and kits. Employing dyed latex polymer particles and adding a water-soluble, non-latex polymer particle absorbing dye contrasting in color to the dyed latex polymer particles produces a reaction mixture that changes color when agglutination occurs. Direct and indirect latex agglutination tests are contemplated which are useful in detecting disease states or physiological states such as pregnancy.
    Type: Grant
    Filed: September 30, 1982
    Date of Patent: December 6, 1983
    Assignee: The Dow Chemical Company
    Inventors: Linneaus C. Dorman, Leigh B. Bangs
  • Patent number: 4387058
    Abstract: Novel phenyl and naphthyl esters of 2-(1-oxo-alkoxy)ethyl carbamic acids are prepared. The compounds are useful as pharmacological and agricultural agents.
    Type: Grant
    Filed: October 2, 1981
    Date of Patent: June 7, 1983
    Assignee: The Dow Chemical Company
    Inventor: Chester E. Pawloski
  • Patent number: 4380649
    Abstract: Novel isophorone derivatives are disclosed and possess utility as insect sterilants, plant growth regulators and fungicides.
    Type: Grant
    Filed: November 23, 1981
    Date of Patent: April 19, 1983
    Assignee: The Dow Chemical Company
    Inventor: Joseph E. Dunbar
  • Patent number: 4356309
    Abstract: Compounds of the formula ##STR1## wherein R.sub.1 represents C.sub.1 to C.sub.20 alkyl-substituted benzyl, orC.sub.2 to C.sub.20 alkyl which can optionally bear one or two --OR.sub.2 radicals, wherein each R.sub.2 independently represents hydrogen or the radical ##STR2## wherein R.sub.3 represents C.sub.1 to C.sub.20 alkyl are disclosed. These compounds are useful for the selective extraction of cobalt, nickel or copper ions from aqueous acidic ore leach liquors.
    Type: Grant
    Filed: July 13, 1981
    Date of Patent: October 26, 1982
    Assignee: The Dow Chemical Company
    Inventors: James W. Lalk, Frances P. Hamburg
  • Patent number: 4336384
    Abstract: In a new method of producing 4-amino-3,5,6-trichloropicolinic acid 3,4,5,6-tetrachloropicolinonitrile is reacted with ammonium hydroxide, preferably at about 130.degree. C. to about 160.degree. C. The free acid is precipitated upon acidification of the reaction mixture and may be recovered therefrom.
    Type: Grant
    Filed: April 23, 1981
    Date of Patent: June 22, 1982
    Assignee: The Dow Chemical Company
    Inventors: Edwin R. Henson, David J. Koranek