Patents Represented by Attorney John McDonnell

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  • Pentanedioic acid derivatives
    Patent number: 4645858
    Abstract: Compounds of formula I are described which are useful to inhibit the formation of serum cholesterol by virtue of their ability to inhibit .beta.-hydroxy-.beta.-methylglutaryl-CoA(HMG CoA), the rate-controlling substance in the synthesis of serum cholesterol.
    Type: Grant
    Filed: October 10, 1985
    Date of Patent: February 24, 1987
    Assignee: G. D. Searle & Co.
    Inventors: Harman S. Lowrie, John S. Baran