Patents Represented by Attorney John S. Nagle

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  • Composition and method of treating depression using naloxone or naltrexone in combination with a serotonin reuptake inhibitor
    Patent number: 5817665
    Abstract: This invention relates to a composition and method for treating depression by administering to a patient a pharmacologically effective dose of an opioid antagonist having a pentacyclic nucleus structurally analogous to naltrexone, and a pharmacologically effective dose of a nontricyclic antidepressant
    Type: Grant
    Filed: November 20, 1995
    Date of Patent: October 6, 1998
    Assignee: John S. Nagle
    Inventor: Lee G. Dante
  • Composition and method of treating depression using natoxone or naltrexone in combination with a serotonin reuptake inhibitor
    Patent number: 5512593
    Abstract: A new composition and method of treating depression includes administering to a depressed patient a pharmacologically effective dose of naloxone or naltrexone or their pharmacologically effective salts and esters in combination with at least one nontricyclic serotonin reuptake inhibitor antidepressant or their pharmacologically effective salts and esters. The patient may while undergoing antidepressant therapy be undergoing treatment with a benzodiazepine for anxiety.
    Type: Grant
    Filed: March 2, 1993
    Date of Patent: April 30, 1996
    Assignee: John S. Nagle
    Inventor: Lee G. Dante