Patents Represented by Attorney, Agent or Law Firm John W. Schneller
  • Patent number: 6228618
    Abstract: Methods for enhancing the production of tissue plasminogen activator (tPA) in cell culture are disclosed. The methods involve culturing tPA-producing cells in growth media supplemented with an alkanoic acid or salt thereof at a concentration which enhances tPA production. The most preferred methods utilize butyric acid or sodium butyrate at a concentration of between 0.5 mM and 2.5 mM.
    Type: Grant
    Filed: October 22, 1997
    Date of Patent: May 8, 2001
    Assignee: Alusuisse Holdings A.G.
    Inventor: Raymond Paul Field
  • Patent number: 6083866
    Abstract: Catalytic system which can be used for the polymerisation of .alpha.-olefins comprising:a solid based on complexed titanium trichloride of .delta. crystalline form;an organoaluminium compound;an organic oxygenated silicon compound; characterised in that the organoaluminium compound is a non-halogenated compound.
    Type: Grant
    Filed: February 6, 1997
    Date of Patent: July 4, 2000
    Assignee: Solvay Polyolefins Europe-Belgium
    Inventors: Jean-Louis Costa, Sabine Pamart, Herve Collette, Serge Bettonville
  • Patent number: 5895803
    Abstract: Statistical propylene copolymer containing 0.2-0.9% by weight monomeric units derived from ethylene; 13-21% by weight monomeric units derived from .alpha.-olefin having 4-10 carbon atoms, and 78.1-86.8% by weight monomeric units derived from propylene. The copolymer has a melting point of 115-125.degree. C.; a proportion of polymer soluble in boiling heptane greater than or equal to 95% by weight, and a proportion of polymer soluble in cold xylene (25.degree. C.) greater than 40% by weight.
    Type: Grant
    Filed: June 25, 1997
    Date of Patent: April 20, 1999
    Assignee: Solvay Polyolefins Europe-Belgium
    Inventors: Veerle Deblauwe, Antonio Belforte, Mathieu Wilkin
  • Patent number: 5863854
    Abstract: A catalyst system for olefin polymerization, including a catalytic solid based on chromium deposited on a support containing silica, alumina and aluminium phosphate and a cocatalyst chosen from organoaluminium compounds. One of the essential characteristics of the invention is the combination of an organoaluminium compound as cocatalyst with a catalytic solid based on chromium deposited on a support containing silica, alumina and aluminium phosphate.
    Type: Grant
    Filed: July 24, 1997
    Date of Patent: January 26, 1999
    Assignee: Solvay Polyolefins Europe-Belgium (Societe Anonyme)
    Inventors: Abel Grosjean, Benoit Koch
  • Patent number: 5350697
    Abstract: An apparatus in which scattered light is measured, said apparatus having a light source aligned to direct illumination toward an interface between a sample container and an aqueous solution at an angle less than the critical angle. A detector to measure the scattered light is located at a place outside the envelope of the critical angle.
    Type: Grant
    Filed: August 28, 1990
    Date of Patent: September 27, 1994
    Assignee: Akzo N.V.
    Inventors: C. Hermas Swope, John G. Link, Jones M. Hyman
  • Patent number: 5316764
    Abstract: The present invention concerns a vaccine comprising a novel canine parvovirus strain and having the property of being able to break through the maternally derived antibody levels persistent in 9-12 week old pups, and even to immunize the majority of pups at the age of 6 weeks in the presence of maternally derived antibodies.
    Type: Grant
    Filed: February 25, 1993
    Date of Patent: May 31, 1994
    Assignee: AKZO N.V.
    Inventor: Jill Walsh
  • Patent number: 4945041
    Abstract: Monoclonal antibodies specific for Mycoplasma pneumoniae determinants and their use in the diagnosis of mycoplasma pneumoniae and purification of a protein determinant of M. pneumoniae.
    Type: Grant
    Filed: January 9, 1987
    Date of Patent: July 31, 1990
    Assignee: Board of Regents
    Inventor: Joel B. Baseman
  • Patent number: 4923970
    Abstract: A substituted 1-(2-chloroethyl)-3-acyl-3-alkyltriazene of the formula: ##STR1## in which R.sub.1 is 1-oxoalkyl containing from two to eight carbon atoms, fluorinated 1-oxoalkyls containing from two to eight carbon atoms and substituted with up to three fluorine atoms, benzoyl, phenylacetyl, carboalkoxy containing from two to eight carbon atoms, fluorinated carboalkyl containing from two to eight carbon atoms and up to three fluorine atoms, carbophenoxy, N-phenyl aminocarbonyl, N-alkyl aminocarbonyl containing from two to eight carbon atoms, thiocarbamoyl, N-alkylthiocarbamoyls with from two to eight carbon atoms, N-phenylthiocarbamoyl, dialkylphosphonates in which the alkyl groups can be the same or different and each contains from one to seven carbon atoms, phenylsulfonyl, and meta or para-substituted phenylsulfonyl in which the meta or para substituent is methyl, ethyl, methoxy, ethoxy, fluoro and chloro; and R.sub.
    Type: Grant
    Filed: March 28, 1988
    Date of Patent: May 8, 1990
    Assignee: Bionetics Research, Inc.
    Inventors: Christopher J. Michejda, Richard H. Smith, Jr.
  • Patent number: 4915686
    Abstract: The invention relates to an injection device, in particular for once-only use, for injecting an implant which can release a drug in a controlled manner, which device comprises a housing which is provided at the injection end with an injection needle in which the implant can be disposed and in which a passage opening is disposed at the actuating end of the housing for a plunger, mounted in the housing and displaceable in the axial direction of the needle, which, on the one hand, can interact with the implant and, on the other hand, is provided with an actuating element, which element is constructed as an element for pressing and supporting against or on the part of the body to be treated.
    Type: Grant
    Filed: July 28, 1988
    Date of Patent: April 10, 1990
    Assignee: Akzo N.V.
    Inventor: Mervyn J. Frederick