Abstract: A method for solubilization and naturation of somatotropin protein from refractile bodies of host cells is disclosed. The method embraces the discovery that an aqueous solution of urea, or dimethylsulfone, or mixtures of urea and dimethylsulfone, can be effectively used to solubilize refractile bodies containing such somatotropin protein. Once solubilized, somatotropin protein can be natured in an aqueous solution of urea, or dimethylsulfone, or mixtures of urea and dimethylsulfone, by contacting the solution with a mild oxidizing agent for a time sufficient to result in the formation of the disulfide bonds. Naturation can efficiently occur even at high protein concentration, in an impure preparation and in the absence of reducing agent.

Abstract: A method for solubilization and naturation of somatotropin protein from refractile bodies of host cells is disclosed. The method embraces the discovery that an aqueous solution of urea, or dimethylsulfone, or mixtures of urea and dimethylsulfone, can be effectively used to solubilize refractile bodies containing such somatotropin protein. Once solubilized, somatotropin protein can be natured in an aqueous solution of urea, or dimethylsulfone, or mixtures of urea and dimethylsulfone, by contacting the solution with a mild oxidizing agent for a time sufficient to result in the formation of the disulfide bonds. Naturation can efficiently occur even at high protein concentration, in an impure preparation and in the absence of reducing agent.

Abstract: Production of N-acetyl-p-aminophenol by hydrogenation of p-nitrophenol to p-aminophenol and concurrently acetylating the p-aminophenol with acetic anhydride with the acetylation controlled so that substantially no excess acetic anhydride is present in the system until the hydrogenation reaction has reached substantial completion.

Abstract: Disclosed are compositions of polyethylene terephthalate and certain N-substituted phthalimide plasticizers, particularly polyethylene terephthalate molding compositions additionally containing a reinforcing agent and a nucleating agent.

Abstract: A tall oil rosin paper sizing composition comprising a homogeneous aqueous liquid which is fully miscible with water at 5.degree. C. On a solids basis, the composition contains between about 15% and about 75% by weight of an alkali metal soap of a condensation product of tall oil rosin and an aldehyde, and between about 85% and about 25% by weight urea. Also disclosed are methods for preparation and use of the novel paper sizing composition.

Abstract: Grafted starch polymer solution of a low viscosity through the use of cinnamic acid material. The cinnamic acid material is incorporated into the grafted starch polymer which is prepared from starch and vinyl monomer, preferably acrylamide.

Abstract: Grafted starch polymer solutions of a low viscosity through the use of cinnamic acid material. The cinnamic acid material is incorporated into the grafted starch polymer which is prepared from starch and vinyl monomer, preferably acrylamide.

Abstract: A grafted starch polymer solution having a lower viscosity through the incorporation of styrene into said grafted starch polymer.

Abstract: A terpolymer comprising repeating units derived from an olefin, a diester of an addition polymerizable unsaturated dicarboxylic acid, and a solubilizing monomer which promotes compatibility between the terpolymer and a vinyl halide polymer. A granular form of the processing aid and a method for its preparation are also disclosed.

Abstract: Solid state compositions having improved storage stability are provided by reacting an aqueous solution or slurry of polymeric acetal carboxylate and alkali metal hydroxide with carbon dioxide to form alkali metal carbonate in intimate admixture with the polymer and recovering the admixture in solid form. The compositions are useful as builders in detergent formulations.

Abstract: Aqueous solutions of aminomethylenephosphonic acid selected from diethylenetriaminepenta(methylenephosphonic acid). diethylenetriaminetetra(methylenephosphonic acid), diethylenetriaminetri(methylenephosphonic acid) and mixtures thereof are stabilized against crystallization of said aminomethylenephosphonic acid by including non-oxidizing mineral acid in such solutions in an amount stoichiometrically equivalent to at least 10% hydrochloric acid by weight of the solution.

Abstract: A process for increasing the color-free shelf life of a crude N-acetyl aminophenol prepared by the acetylation of an aminophenol wherein the N-acetyl aminophenol contains color-forming impurities which are the products of oxidation of the aminophenol and other side reactions. The process comprises dissolving the crude N-acetyl aminophenol in a solvent containing a reducing agent, heating the solution at about the boiling point, crystallizing the N-acetyl aminophenol from the solution, washing the crystalline N-acetyl aminophenol with solvent containing reducing agent and thereafter separating and drying the crystalline N-acetyl aminophenol.

Abstract: Crude vanillin is purified by supercritical extraction of impurities. The process is especially useful in purifying crude vanillin obtained from paper mill waste liquors. Preferred supercritical extraction fluid is CO.sub.2.

Abstract: The invention is a new family of phosphine compounds which can be used to make optically active metal coordination complex catalysts which combine high efficiency with a capability of performing rapidly (high efficiency and rapidly being established from Tables I, II and III as being greater than 75% efficiency and in times of not more than a few hours, preferably less than one hour) in water and thus avoiding solvent recovery and loss problems. The catalysts can be used in some alcoholic mediums as well as in some aqueous mediums. These catalysts are useful in catalytic asymmetric hydrogenation of some olefinic compounds. The new phosphine compounds are made from novel phosphine oxides.

Abstract: Aqueous compositions thickened by galactomannan gums are described which are stabilized by soluble molybdenum.

Abstract: A free flowing granulation, comprising a high concentration of acetaminophen and a low level of excipient, including ground cross-linked sodium carboxymethylcellulose fiber, allows the manufacture of analgesic tablets by direct compression. The method provides improvements in manufacturing economics and tablet properties.

Abstract: A process is disclosed for producing chlorinated trisodium phosphate, comprising:(a) producing a hot sodium phosphate liquor, preferably with an overall Na/P mole ratio from 2.60 to 2.85;(b) adding sodium hypochlorite solution, preferably with an available chlorine content greater than 14%;(c) mixing the components, preferably from 70.degree. C. to 80.degree. C., only long enough to form a true solution;(d) cooling the melt by evaporative cooling under reduced pressure to form crystalline chlorinated trisodium phosphate;(e) air drying the product, if necessary, below about 40.degree. C.

Abstract: The concentration of chlorine-containing compounds in a gaseous mixture in contact with a solid chloroisocyanurate can be safely lowered by use of a porous crystalline alumino-silicate having an essentially uniform pore size and a free aperture dimension of at least about 3.5 angstroms, said alumino-silicate being essentially unreactive with the chloroisocyanurate and its hydrolysis and decomposition products.

Abstract: A method for stabilizing color, inhibiting color development, and reducing color of monoalkyl phenols by incorporation of N,N-diethylhydroxylamine, preferably from about 5 parts per million to about 50 parts per million. Also a color stabilized monoalkyl phenol composition comprising a monoalkyl phenol and a color stabilizing amount of N,N-diethylhydroxylamine.

Abstract: An acrylamide polymer comprising acrylamide and a sufficient amount of cinnamic acid to substantially reduce the viscosity of the acrylamide polymer and solution.