Patents Represented by Attorney, Agent or Law Firm Jonathan Grant
  • Patent number: 6824975
    Abstract: This invention discloses a method and composition for detecting the presence of class specific antibodies reactive with analytes such as bacteria, allergens, autoimmune antigens, viral proteins, and carbohydrates by lateral flow techniques. In one embodiment of the invention, a test sample obtained from bodily fluids reacts with a gold labeled antigen. The resulting complex travels across the membrane, and along the lateral flow strip. Red colored lines formed in specific locations along the test strip indicate the presence of class specific antibodies in the test specimen. In another embodiment of the invention, the lateral flow assay serves as an immunochromatographic screening test for the detection of allergen-specific IgE antibodies in human serum. Test sample reacts with gold labeled anti-IgE antibody. The resulting complex travels across the membrane where immobilized allergens capture the allergen specific IgE complex.
    Type: Grant
    Filed: October 12, 2001
    Date of Patent: November 30, 2004
    Assignee: Dexall Biomedical Labs, Inc
    Inventors: Thomas T. Hubscher, Glen M Ford, Teri M Ruppenthal
  • Patent number: 6752988
    Abstract: A method for the prophylactic and therapeutic treatment of bacterial infections is disclosed which comprises the treatment of an individual with an effective amount of a native or modified version of a lytic enzyme produced by a bacteria infected with a bacteriophage specific for said bacteria. The lytic enzyme is selected from a group consisting of shuffled lytic enzymes, chimericlytic enzymes, wherein the lytic enzyme is in an environment having a pH which allows for activity of said lytic enzyme; and a carrier for delivering said lytic enzyme. Additionally, a holin enzyme for puncturing the membrane may be included in the composition. This method, and composition can be used for the treatment of upper respiratory infections, skin infections, wounds, and burns, vaginal infections, eye infections, intestinal disorders and dental problems.
    Type: Grant
    Filed: April 28, 2000
    Date of Patent: June 22, 2004
    Assignees: New Horizons Diagnostic Corp, Rockefeller University
    Inventors: Vincent Fischetti, Lawrence Loomis
  • Patent number: 6742780
    Abstract: This invention discloses a skateboard maze game comprising a board having a surface, an underside, a front section, and a back section at least one maze grooved into the surface of the board, at east one ball per maze which fits into the grooves, and at least one ground support element. The board is positioned on top of wheels, half wheels or some other supporting structure, allowing an individual standing on the board to move the board around to work the maze.
    Type: Grant
    Filed: December 3, 2002
    Date of Patent: June 1, 2004
    Inventor: Lewis Rudski
  • Patent number: 6737079
    Abstract: A composition for treatment of bacterial infections of burns and wounds of the skin, comprising an effective amount of at least one lytic enzyme produced by a bacteria infected with a bacteriophage specific for said bacteria, and a carrier for delivering said at least one lytic enzyme to the skin. The carrier may be, but is not limited to, a liquid solution applied to a bandage.
    Type: Grant
    Filed: August 20, 2001
    Date of Patent: May 18, 2004
    Assignees: New Horizons Diagnostics Corporation, Rockefeller University
    Inventors: Vincent Fischetti, Lawrence Loomis
  • Patent number: 6733749
    Abstract: A lozenge for the treatment of Hemophilus influenzae infections of the mouth throat and nasal passage is disclosed which comprises a lytic enzyme composition specific for Hemophilus influenzae, and a lozenge carrier for delivering said lytic enzyme.
    Type: Grant
    Filed: February 27, 2002
    Date of Patent: May 11, 2004
    Assignees: New Horizons Diagnostics Corporation, Rockefeller University
    Inventors: Vincent Fischetti, Lawrence Loomis
  • Patent number: 6685937
    Abstract: A chewing gum composition produced by mixing an effective amount of lysin enzyme produced by group C streptococcal bacteria infected with a C1 bacteriophage and a carrier for delivering said lysin enzyme to a mouth, throat, or nasal passage.
    Type: Grant
    Filed: May 25, 2001
    Date of Patent: February 3, 2004
    Assignees: New Horizons Diagnostics Corp., Rockefeller University
    Inventors: Vincent Fischetti, Lawrence Loomis
  • Patent number: 6658188
    Abstract: A dry optical fiber cable, for voice, video and data telecommunication based on a plurality of a loosely fitted tubes placed longitudinally and surrounding a central reinforcement element, said tubes accommodating at least one or several optical fiber filaments. This dry optical fiber cable is characterized because in the internal area, between the central reinforcement element and the plurality of tubes, it has a first dry protection layer; the interior assembly is then externally protected by a second dry protection. It then has a polyethylene cover followed by the third dry protection and finally a polyethylene cover.
    Type: Grant
    Filed: December 18, 2001
    Date of Patent: December 2, 2003
    Assignee: Condumex
    Inventor: Ruben Mandujano Lopez
  • Patent number: 6592424
    Abstract: The invention discloses colorful wind indicator toys and kites having an improved mechanism for securing a hollow rotatable rod containing mechanisms for various rotatable wind collecting parts of the wind indicators and kites. More specifically, it is proposed that a snap lock be used instead of a disk type structure to secure certain hollow rotatable rods onto the frames of wind indicator toys, thereby preventing rods from disengaging and flying away from the structure during high winds.
    Type: Grant
    Filed: July 25, 2002
    Date of Patent: July 15, 2003
    Assignee: Go Fly a Kite
    Inventor: James Christianson
  • Patent number: 6564537
    Abstract: The invention relates to a ring twisting and winding spinning machine with autonomous and independent unitary production modules.
    Type: Grant
    Filed: August 24, 2001
    Date of Patent: May 20, 2003
    Assignee: Galan Textile Machinery
    Inventor: Jose Galan Pujol
  • Patent number: 6528325
    Abstract: This invention discloses a method and composition for detecting the presence of class specific antibodies reactive with analytes such as bacteria, allergens, autoimmune antigens, viral proteins, and carbohydrates by lateral flow techniques. In one embodiment of the invention, a test sample obtained from bodily fluids reacts with a gold labeled antigen. The resulting complex travels across the membrane, and along the lateral flow strip. Red colored lines formed in specific locations along the test strip indicate the presence of class specific antibodies in the test specimen. In another embodiment of the invention, the lateral flow assay serves as an immunochromatographic screening test for the detection of allergen-specific IgE antibodies in human serum. Test sample reacts with gold labeled anti-IgE antibody. The resulting complex travels across the membrane where immobilized allergens capture the allergen specific IgE complex.
    Type: Grant
    Filed: October 13, 2000
    Date of Patent: March 4, 2003
    Assignee: Dexall Biomedical Labs, Inc.
    Inventors: Thomas T. Hubscher, Glen M Ford, Teri M Ruppenthal
  • Patent number: 6520824
    Abstract: A balloon toy vehicle is disclosed which has full direction control, altitude control and a motorized release feature that permits an object to be lifted and dropped remotely. Fixed tandem reversible thruster motors are positioned approximately perpendicular to the gondola body of the vehicle and work in tandem to provide forward, reverse, left turn and right turn movements. A third thruster motor is positioned along the length of the gondola body facing downward to provide lift. In a preferred embodiment, the lift thruster motor, is positioned slightly angularly from a vertical longitudinal plane passing through the gondola body and is attached to the gondola body by a bracket. This motor arrangement gives the vehicle both lift and anti-spin stability. An adjustment feature is provided to set the gondola body in a horizontal plane. This accommodates any variations in the fixed balloon connection. The vehicle is preferably operated by wireless remote control.
    Type: Grant
    Filed: June 13, 2000
    Date of Patent: February 18, 2003
    Assignee: Toytronix
    Inventor: Rom Caroselli
  • Patent number: 6509526
    Abstract: A telephone lead in cable for high performance voice, video, data transmission, and lead in services, having a generally rectangular shaped housing made of thermoplastic material, a data transmission circuit, capable of transmitting data at high speeds, that has two metal wires which are helically twisted about one another, a fusion protection thin band made of heat resistant material that is applied helically or longitudinally on the two metal wires, wherein the two metal wires are positioned to run through the center of the housing, and a circuit element for voice transmission having two metal conductors that are parallel to each other and positioned on an opposite side of the centrally located helically twisted thermoplastic covered wires.
    Type: Grant
    Filed: March 13, 2001
    Date of Patent: January 21, 2003
    Assignee: Servicies Conoumex S.A. Dec.V.
    Inventors: Victor Osornio Osornio, Fermin Marquez Arzate
  • Patent number: 6432444
    Abstract: A bandage for treating a bacterial infection of skin is disclosed wherein the bandage contains a composition produced by the method of obtaining an effective amount of at least one lytic enzyme genetically coded for by a specific bacteriophage specific for a bacteria infecting the skin, wherein the bacteria to be treated is selected from the group consisting of Staphylococcus, Pseudomonas, Streptococcus, and combinations thereof. This lytic enzyme is specific for and has the ability to digest a cell wall of one of the bacteria and is coded for by the same bacteriophage capable of infecting the bacteria being digested. The enzyme produced is mixed with a topical carrier.
    Type: Grant
    Filed: September 28, 2000
    Date of Patent: August 13, 2002
    Assignee: New Horizons Diagnostics Corp
    Inventors: Vincent Fischetti, Lawrence Loomis
  • Patent number: 6428784
    Abstract: A composition for treatment of bacterial infections of the vagina is disclosed which comprises a lytic enzyme composition specific for the infecting bacteria, and a carrier for delivering said lytic enzyme. The lytic enzyme is which is specific for the group B Streptococcus, is genectically coded for by a specific bacteriophage.
    Type: Grant
    Filed: September 28, 2000
    Date of Patent: August 6, 2002
    Assignee: New Horizons Diagnostics Corp
    Inventors: Vincent Fischetti, Lawrence Loomis
  • Patent number: 6399097
    Abstract: An enteric coated pill for treating bacterial infections of the digestive tract, wherein the bacteria to be treated are selected from the group consisting of Listeria, Salmonella, E. coli, Campylobacter and combinations thereof, said pill comprising an effective amount of at least one lytic enzyme genetically coded by a bacteriophage specific for said bacteria of the digestive tract, whereby said enzyme has the ability to digest the cell wall of said bacteria; and a carrier for said enzyme.
    Type: Grant
    Filed: September 1, 2000
    Date of Patent: June 4, 2002
    Assignee: New Horizons Diagnostics Corporation
    Inventors: Vincent Fischetti, Lawrence Loomis
  • Patent number: 6395504
    Abstract: A method for the use of a phage associated lysing enzyme for the detecting the presence and determining the quantity of bacteria present in or on a wide variety of substances is described. The total concentration of microbes is determined by adding or incorporating a phage associated lytic agent to a disposable test system device with the luminescent reagents luciferin and luciferase, and introducing the disposable test system into a luminometer that can read the luminescence. Other systems can be used with the lytic enzymes for the quantitative and qualitative determination for the presence of bacteria.
    Type: Grant
    Filed: September 1, 2000
    Date of Patent: May 28, 2002
    Assignee: New Horizons Diagnostics Corp.
    Inventor: David Trudil
  • Patent number: 6277399
    Abstract: A composition for treatment of bacterial infections of burns and wounds of the skin comprises an effective amount of at least one lytic enzyme produced by a bacteria infected with a bacteriophage specific for said bacteria, and a carrier for delivering said at least one lytic enzyme to the skin. The carrier may be, but is not limited to, a liquid solution applied to a bandage.
    Type: Grant
    Filed: September 28, 2000
    Date of Patent: August 21, 2001
    Assignee: New Horizon Diagnostics Corporation
    Inventors: Vincent Fischetti, Lawrence Loomis
  • Patent number: 6254866
    Abstract: A method for treatment of bacterial infections of the digestive tract is disclosed which comprises administering a lytic enzyme specific for the infecting bacteria. The lytic enzyme is preferably in a carrier for delivering said lytic enzyme. The bacteria to be treated is selected from the group consisting of Listeria, Salmonella, E. coli, Campylobacter, and combinations thereof. The carrier for delivering at least one lytic enzyme to the digestive tract is selected from the group consisting of suppository enemas, syrups, or enteric coated pills.
    Type: Grant
    Filed: September 1, 2000
    Date of Patent: July 3, 2001
    Assignee: New Horizons Diagnostics Corporation
    Inventors: Vincent Fischetti, Lawrence Loomis
  • Patent number: 6238661
    Abstract: Compositions and methods for the prophylactic and therapeutic treatment of bacterial infections are disclosed which comprise administering to an individual an effective amount of a composition comprising an effective amount of lytic enzyme and a carrier for delivering the lytic enzyme. This method and composition can be used for the treatment of upper respiratory infections, skin infections, wounds, burns, vaginal infections, eye infections, intestinal disorders and dental problems.
    Type: Grant
    Filed: April 18, 2000
    Date of Patent: May 29, 2001
    Assignee: New Horizons Diagnostics Corp.
    Inventors: Vincent Fischetti, Lawrence Loomis
  • Patent number: 6218808
    Abstract: An apparatus and method for fast battery charging are provided. A fast battery charger applies high charging current to a battery to minimize charging time. Micropeak detection of the battery voltage prevents overcharging of the battery cells, thereby preventing degradation of battery capacity over time. Noise reduction throughout the system as well as improved detection resolution allows for micropeak detection. A linear power supply eliminates switch noise. The sampling frequency is synchronized with the power supply, eliminating error due to power supply variation. Sleeping sampling is performed to overcome noise due to operation of the CPU. Improved measurement resolution is obtained via a 10-bit analog to digital converter. A subtraction technique maintains the high measurement resolution.
    Type: Grant
    Filed: March 24, 2000
    Date of Patent: April 17, 2001
    Assignee: Model Rectifier Corporation
    Inventor: Zhiping Lin