Abstract: The invention relates to compounds of the formula to processes for the preparation thereof, and to the use thereof for treatment and/or prophylaxis of cardiovascular diseases and tumour diseases.
Type:
Grant
Filed:
May 27, 2010
Date of Patent:
June 19, 2012
Assignee:
Bayer Intellectual Property GmbH
Inventors:
Dirk Heimbach, Susanne Röhrig, Yolanda Cancho Grande, Eckhard Bender, Katja Zimmermann, Anja Buchmüller, Christoph Gerdes, Mark Jean Gnoth, Kersten Matthias Gericke, Mario Jeske
Abstract: The invention relates to novel substituted oxazolidinones, to processes for preparation thereof, to the use thereof for treatment and/or prophylaxis of diseases, and to the use thereof for producing medicaments for treatment and/or prophylaxis of diseases, especially of thromboembolic disorders.
Type:
Grant
Filed:
June 13, 2008
Date of Patent:
June 12, 2012
Assignee:
Bayer Intellectual Property GmbH
Inventors:
Swen Allerheiligen, Marcus Bauser, Hartmut Schirok, Michael Härter, Stephan Siegel, Ulrich Rester, Christoph Gerdes, Stefan Heitmeier, Georges Von Degenfeld, Anja Buchmüller, Elke Dittrich-Wengenroth, Uwe Saatman, Julia Strassburger, Mark Jean Gnoth, Dieter Lang
Abstract: The present application relates to a novel tetrahydroquinoline derivative, to a process for its preparation, to its use on its own or in combination for treating and/or preventing diseases and to its use for preparing medicaments, in particular as an inhibitor of the cholesterol ester transfer protein (CETP) for the treatment and/or prevention of cardiovascular disorders, in particular hypolipoproteinaemias, dyslipidaemias, hypertriglyceridaemias, hyperlipidaemias, hypercholesterolaemias and arteriosclerosis.
Type:
Grant
Filed:
December 15, 2005
Date of Patent:
February 28, 2012
Assignee:
Bayer Pharma Aktiengesellschaft
Inventors:
Hilmar Bischoff, Heike Gielen-Haertwig, Volkhart Li, Carsten Schmeck, Michael Thutewohl, Alexandros Vakalopoulos, Olaf Weber, Martina Wuttke
Abstract: The invention relates to novel heterocyclic derivatives of the general formula (I), processes for their preparation, and their use in medicaments, especially for the treatment of chronic obstructive pulmonary diseases, acute coronary syndrome, acute myocardial infarction and heart failure development.
Type:
Grant
Filed:
February 15, 2005
Date of Patent:
January 24, 2012
Assignee:
Bayer Pharma Aktiengesellschaft
Inventors:
Heike Gielen-Haertwig, Barbara Albrecht, Jörg Keldenich, Volkhart Li, Josef Pernerstorfer, Karl-Heinz Schlemmer, Leila Telan
Abstract: The present application relates to a novel tetrahydroquinoline derivative, to a process for its preparation, to its use on its own or in combination for treating and/or preventing diseases and to its use for preparing medicaments, in particular as an inhibitor of the cholesterol ester transfer protein (CETP) for the treatment and/or prevention of cardiovascular disorders, in particular hypolipoproteinaemias, dyslipidaemias, hypertriglyceridaemias, hyperlipidaemias, hypercholesterolaemias and arteriosclerosis.
Type:
Grant
Filed:
December 15, 2005
Date of Patent:
October 18, 2011
Assignee:
Bayer Pharma Aktiengesellschaft
Inventors:
Hilmar Bischoff, Heike Gielen-Haertwig, Volkhart Li, Carsten Schmeck, Michael Thutewohl, Alexandros Vakalopoulos, Olaf Weber, Martina Wuttke
Abstract: The present application relates to novel 4-chromenonyl-1,4-dihydropyridines, process for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially cardiovascular disorders.