Patents Represented by Attorney, Agent or Law Firm Jonathon Alan Quine
  • Evolution of whole cells and organisms by recursive sequence recombination
    Patent number: 6379964
    Abstract: The invention provides methods employing iterative cycles of recombination and selection/screening for evolution of whole cells and organisms toward acquisition of desired properties. Examples of such properties include enhanced recombinogenicity, genome copy number, and capacity for expression and/or secretion of proteins and secondary metabolites.
    Type: Grant
    Filed: July 15, 1999
    Date of Patent: April 30, 2002
    Assignee: Maxygen, Inc.
    Inventors: Stephen del Cardayre, Matthew Tobin, Willem P. C. Stemmer, Jeremy Minshull