Patents Represented by Attorney Jone Day
  • Patent number: 8349814
    Abstract: The present invention provide compounds, and pharmaceutical compositions thereof, encompassed by the formulae (I), (II) or (III). The present invention also provides methods for treating an FAAH mediated disease, disorder or condition by administering a therapeutically effective amount of a provided compound of the formulae (I), (II) or (III), or a pharmaceutical composition thereof, to a patient in need thereof. Additionally, the present invention provides methods for inhibiting FAAH in a patient by administering a therapeutically effective amount of a compound of the formulae (I), (II) or (III), or a pharmaceutical composition thereof, to a patient in need thereof.
    Type: Grant
    Filed: March 16, 2011
    Date of Patent: January 8, 2013
    Assignee: Infinity Pharmaceuticals, Inc.
    Inventors: Julian Adams, Mark L. Behnke, Alfredo C. Castro, Catherine A. Evans, Louis Grenier, Michael J. Grogan, Tao Liu, Daniel A. Snyder, Thomas T. Tibbitts
  • Patent number: 8348674
    Abstract: A method, system and computer-readable carrier for using a discrimination index to select test items from an item bank for a test are disclosed. At least one parameter may be identified for each of a plurality of test items in an item bank. A first test item may be selected from the item bank based on at least the parameter for the test item. Each unselected test item may be evaluated to determine whether one or more constraints would be satisfied if the test item were selected. A next test item may be selected from the unselected test items that satisfy the one or more first constraints based on at least the parameter for each test item. The Evaluation and test item selection processes may be repeated until one or more second constraints are satisfied.
    Type: Grant
    Filed: August 12, 2005
    Date of Patent: January 8, 2013
    Assignee: Educational Testing Service
    Inventor: Robert Aaron Henson
  • Patent number: 8351843
    Abstract: A method for specifying content of interest using a digital radio broadcast receiver is described. A digital radio broadcast signal includes first audio content and first program data, wherein the first program data includes information identifying a first item, and includes second audio content and second program data, wherein the second program data includes information identifying a second item. A user command entered at a user interface during reception of audio content is registered, indicating a user's interest in either the first or second audio content. It is determined whether there is an ambiguity in the content of interest. If there is an ambiguity, a first data structure is stored for the first audio content, and a second data structure is stored for the second audio content. The first data structure includes the information identifying the first item, and the second data structure includes the information identifying the second item.
    Type: Grant
    Filed: September 4, 2007
    Date of Patent: January 8, 2013
    Assignee: iBiquity Digital Corporation
    Inventors: Robert Michael Dillon, Harvey Chalmers, Thomas Joseph O'Brien, Gregory Nungester, Rodney Bernard Burke, Joseph F. D'Angelo
  • Patent number: 8348540
    Abstract: A writing instrument that includes an ink reservoir and a writing tip fluidly connected to the reservoir and through which the ink comes out during use of the instrument. The reservoir contains, in addition to the ink, grains that are separate and that may have angles and sharp edges of dimensions that are significant relative to an apparent dimension (d) of the grains.
    Type: Grant
    Filed: January 12, 2007
    Date of Patent: January 8, 2013
    Assignee: Societe BIC
    Inventors: Vincent Bedhome, Didier Lange, Franck Rolion
  • Patent number: 8349319
    Abstract: The invention relates to dose escalation enzyme replacement therapy using acid sphingomyelinase (ASM) for the treatment of human subjects having acid sphingomyelinase deficiency (ASMD), and, in particular, patients with non-neurological manifestations of Niemann-Pick Disease (NPD), and in certain embodiments, NPD type B.
    Type: Grant
    Filed: August 28, 2010
    Date of Patent: January 8, 2013
    Assignees: Mount Sinai School of Medicine, Genzyme Corporation
    Inventors: Edward H. Schuchman, Robert J. Desnick, Gerald F. Cox, Laura P. Andrews, James M. Murray
  • Patent number: 8352738
    Abstract: Phishing attacks succeed by exploiting a user's inability to distinguish legitimate websites from spoofed websites. Most prior work focuses on assisting the user in making this distinction; however, users must make the right security decision every time. Unfortunately, humans are ill-suited for performing the security checks necessary for secure site identification, and a single mistake may result in a total compromise of the user's online account. Fundamentally, users should be authenticated using information that they cannot readily reveal to malicious parties. Placing less reliance on the user during the authentication process enhances security and eliminates many forms of fraud. We disclose using a trusted device to perform mutual authentication that eliminates reliance on perfect user behavior, thwarts Man-in-the-Middle attacks after setup, and protects a user's account even in the presence of keyloggers and most forms of spyware.
    Type: Grant
    Filed: December 3, 2007
    Date of Patent: January 8, 2013
    Assignee: Carnegie Mellon University
    Inventors: Bryan Parno, Cynthia Kuo, Adrian Perrig
  • Patent number: 8349307
    Abstract: The invention provides polymer conjugates of opioid antagonists comprising a polymer, such as poly(ethylene glycol), covalently attached to an opioid antagonist. The linkage between the polymer and the opioid antagonist is preferably hydrolytically stable. The invention also includes a method of treating one or more side effects associated with the use of opioid analgesics, such as constipation, nausea, or pruritus, by administering a polymer conjugate of the invention.
    Type: Grant
    Filed: October 6, 2009
    Date of Patent: January 8, 2013
    Assignee: Nektar Therapeutics
    Inventors: Michael David Bentley, Michael James Roberts, Xiaoming Shen, Lin Cheng
  • Patent number: 8349851
    Abstract: Provided herein are quinazoline compounds of formula (I): The compounds are useful for treatment of JAK kinase mediated diseases, including JAK2 kinase-, JAK3 kinase- or TYK2 kinase-mediated diseases. Also provided are pharmaceutical compositions comprising the compounds and methods of using the compounds and compositions.
    Type: Grant
    Filed: February 26, 2010
    Date of Patent: January 8, 2013
    Assignee: Ambit Biosciences Corp.
    Inventors: Sunny Abraham, Qi Chao, Michael J. Hadd, Mark W. Holladay, Gang Liu, Eduardo Setti
  • Patent number: 8348504
    Abstract: A temperature measurement system capable of operating in harsh environments including a temperature sensor having an antenna, diode, and dielectric layer disposed on the object of interest is provided, wherein the antenna includes a buried portion that extends through and is electrically coupled to the object of interest, and an exposed portion disposed upon an outer surface of the dielectric layer and the diode is coupled between the object of interest and the exposed portion of the antenna. The antenna is configured to receive interrogating signals from a transmitter, and to transmit response signals corresponding to the resonant frequency of the temperature sensor and its harmonics, which are indicative of the measured temperature of the object of interest. A receiver detects the response signals and correlates the frequency to a known temperature response of the dielectric material. Methods of making and using the temperature measurement system are also provided.
    Type: Grant
    Filed: May 12, 2010
    Date of Patent: January 8, 2013
    Assignee: Wireless Sensor Technologies, LLC
    Inventors: Otto J. Gregory, John R. Conkle, Thomas J. Birnbaum
  • Patent number: 8349578
    Abstract: Provided are hydrolases, including lipases, saturases, palmitases and/or stearatases, and polynucleotides encoding them, and methods of making and using these polynucleotides and polypeptides. Further provided are polypeptides, e.g., enzymes, having a hydrolase activity, e.g., lipases, saturases, palmitases and/or stearatases and methods for preparing low saturate or low trans fat oils, such as low saturate or low trans fat animal or vegetable oils, e.g., soy or canola oils.
    Type: Grant
    Filed: April 8, 2011
    Date of Patent: January 8, 2013
    Assignee: Bunge Oils, Inc.
    Inventors: Christopher L. G. Dayton, Tim Hitchman, Katie Kline, Jonathan Lyon, Mark A. Wall, Nelson R. Barton
  • Patent number: 8346691
    Abstract: Computer-implemented systems and methods for determining a subset of unknown targets to investigate. For example, a method can be configured to receive a target data set, wherein the target data set includes known targets and unknown targets. A supervised model such as a neural network model is generated using the known targets. The unknown targets are used with the neural network model to generate values for the unknown targets. Analysis with an unsupervised model is performed using the target data set in order to determine which of the unknown targets are outliers. A comparison of list of outlier unknown targets is performed with the values for the unknown targets that were generated by the neural network model. The subset of unknown targets to investigate is determined based upon the comparison.
    Type: Grant
    Filed: September 6, 2007
    Date of Patent: January 1, 2013
    Assignee: SAS Institute Inc.
    Inventors: Revathi Subramanian, Vijay S. Desai, Hongrui Gong
  • Patent number: 8344643
    Abstract: Driver system and method for multiple cold-cathode fluorescent lamps and/or external-electrode fluorescent lamps. According to an embodiment, the present invention provides a system for driving a plurality of cold-cathode fluorescent lamps. The system includes a subsystem configured to receive at least a DC voltage and generate a first AC voltage in response to at least the DC voltage. The system also includes a power converter configured to receive the first AC voltage and convert the first AC voltage to at least a second AC voltage. The system further includes a plurality of current balancing devices. Each of the plurality of current balancing devices is configured to receive two currents and balance the two currents. The plurality of current balancing devices includes at least a first current balancing device, a second current balancing device, and a third current balancing device. In addition, the system includes a plurality of lamp pairs.
    Type: Grant
    Filed: April 21, 2010
    Date of Patent: January 1, 2013
    Assignee: On-Bright Electronic (Shanghai) Co., Ltd.
    Inventors: Lieyi Fang, Changshan Zhang, Zhiliang Chen, Shifeng Zhao
  • Patent number: 8343937
    Abstract: A method and composition for treating a host infected with flavivirus or pestivirus comprising administering an effective flavivirus or pestivirus treatment amount of a described 1?, 2? or 3?-modified nucleoside or a pharmaceutically acceptable salt or prodrug thereof, is provided.
    Type: Grant
    Filed: September 25, 2006
    Date of Patent: January 1, 2013
    Assignees: Idenix Pharmaceuticals, Inc., Universita Degli Studi di Cagliari
    Inventors: Jean-Pierre Sommadossi, Paulo LaColla
  • Patent number: 8343555
    Abstract: The present invention relates to a composition and method for treating or preventing white spot syndrome virus of arthropod. The present invention is based on using Artemisia japonica extract, and preferably, a mixture of Artemisia japonica extract and Saururus chinensis extract as effective agent. More preferably, the present invention provides a composition for treating or preventing white spot syndrome virus, comprising Artemisia japonica extract and Saururus chinensis extract which are coated by a polymer. The present invention also provides a method for treating or preventing white spot syndrome virus of arthropod, using Artemisia japonica extract and Saururus chinensis extract which are coated by a polymer.
    Type: Grant
    Filed: May 29, 2007
    Date of Patent: January 1, 2013
    Assignee: CTC Bio, Inc.
    Inventors: Hwa-Gyun Oh, Ki-Hong Sung, Hong-Ryeol Jeon, Hong-Suk Kye, Se-Geun Yu, Dong-Jin Ha
  • Patent number: 8344715
    Abstract: System and method for providing frequency control to a power converter. The system includes a controller configured to receive a load signal and generate a first control signal. The load signal indicates an output load for a power converter. Additionally, the system includes a signal generator configured to receive the first control signal and generates at least a first output signal. The first output signal is associated with a first signal strength and a first frequency. The first frequency is inversely proportional to a sum of a first time period, a second time period, and a third time period. The first signal strength increases with the time during the first time period, the first signal strength decreases with the time during the second time period, and the first signal strength is constant with respect to the time during the third time period.
    Type: Grant
    Filed: August 4, 2010
    Date of Patent: January 1, 2013
    Assignee: On-Bright Electronics (Shanghai) Co., Ltd.
    Inventors: Jun Ye, Zhen Zhu, Shifeng Zhao, Lieyi Fang, Zhiliang Chen
  • Patent number: 8344073
    Abstract: Provided herein are telechelic polymers and methods for producing the same. In some embodiments, provided herein are compounds having the formula and methods for producing the same.
    Type: Grant
    Filed: January 16, 2009
    Date of Patent: January 1, 2013
    Assignee: The University of Southern Mississippi
    Inventors: Robson F. Storey, David L. Morgan
  • Patent number: 8343967
    Abstract: Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-2 proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-2 protein.
    Type: Grant
    Filed: April 27, 2012
    Date of Patent: January 1, 2013
    Assignee: Abbott Laboratories
    Inventors: Hong Ding, Steven W. Elmore, Laura A. Hexamer, Aaron R. Kunzer, Cheol-Min Park, Andrew J. Souers, Gerard M. Sullivan, Michael D. Wendt
  • Patent number: 8347390
    Abstract: A messaging server forwards emails to mobile communication devices of users to whom the emails were respectively addressed. An antivirus server determines whether an email addressed to a user of a mobile communication device, to be forwarded by the messaging server to the mobile communication device, is infected with a virus. In response to determining the email is infected with a virus, a bulletin generator transmits, to the mobile communication devices besides the mobile communication device of the addressee of the email determined to be infected, an all points bulletin message disclosing the existence of the virus. The bulletin message is transmitted directly to, instead of via email to, the wireless mobile communication devices.
    Type: Grant
    Filed: May 11, 2010
    Date of Patent: January 1, 2013
    Assignee: Research In Motion Limited
    Inventors: William D. Castell, Allan D. Lewis, Tabitha K. Ferguson, Bill Yuan, Ian M. Patterson
  • Patent number: 8346295
    Abstract: In accordance with the teachings described herein, systems and methods are provided for implementing a dual-mode keypad for a mobile device. The keypad may operate in a telephony mode and a text-entry mode. The keypad may include a plurality of dual-mode keys that each include an associated telephony character and at least one associated text-entry character. The dual-mode keys may include one or more toggle keys, with each toggle key having a plurality of associated text-entry characters and one associated telephony character. The dual-mode keys may be partially covered by the keypad surface so that a plurality of key surfaces extend from the key and protrude through the keypad surface. In text-entry mode, the dual-mode keys are operable to input text-entry characters. In telephony mode, the dual-mode keys are operable to input telephony characters.
    Type: Grant
    Filed: August 13, 2007
    Date of Patent: January 1, 2013
    Assignee: Research In Motion Limited
    Inventors: Jason T. Griffin, Mihal Lazaridis, Frank M. Tyneski
  • Patent number: 8345856
    Abstract: A method for determining a number of calls to generate in an automated contact center, wherein the automated contact center comprises a dialer for dialing generated calls and an agent pool where successfully connected dialed calls are handled by agents. The method collects empirical data on durations in which calls spend in the dialer and agent handling times. The collected data is used to generate discrete density or discrete distribution functions. Using the discrete density or distribution functions, an individual impact is calculated for each call presently in the dialer. The method uses the individual impacts to calculate a dialer impact, which is used to predict a future agent occupancy. Based upon the prediction, a number of calls to generate is determined. Calls are generated based upon the number of calls to generate.
    Type: Grant
    Filed: December 21, 2011
    Date of Patent: January 1, 2013
    Assignee: Five9, Inc.
    Inventors: Nikolay Anisimov, Dmitry Spasibenko, Sam Shkrabov, David Van Everen