Abstract: A nuclear reactor having a chemical decontamination clean-up system is provided in which every component of the chemical decontamination clean-up equipment which processes radioactive fluids is located within a shielded room of an existing on-site support building. Those components of the clean-up system not in direct contact with radioactive fluids are housed in portable trailers. The decontamination clean-up system is designed to provide for adequate shielding to minimize personnel exposure and also incorporates a modular design for component transportation and storage.