Patents Represented by Attorney Joseph E. Mueth
  • Patent number: 4387137
    Abstract: A novel laminate adapted for use in the manufacture of capacitors comprising layers of microthin pin-hole free electroformed copper bonded together by a thin layer of hardened dielectric material, said bonded surfaces of said microthin copper having first been treated to form thereon a superficial coating of cupric oxide, bonded to the outer surfaces of said microthin copper, layers of self-sustaining copper foil, the bonded surfaces of said copper foil having been passivated under reducing or cathodic conditions in an aqueous solution of chromic oxide to passivate the surface thereof and to render said copper foil peelably removable from said microthin copper.
    Type: Grant
    Filed: December 1, 1980
    Date of Patent: June 7, 1983
    Assignee: The Mica Corporation
    Inventor: James M. Rice
  • Patent number: 4370484
    Abstract: A novel antimicrobial agent having the formula: ##STR1## The new antimicrobial agent may exist as the dihydrochloride salt, as shown or as tautomers of the structure, or in the form of other salts and derivatives such as amides and is normally associated with water of crystallization.The novel antimicrobial agent is obtained from Agelas sceptrum, Agelas conifera, Agelas schmidti, an unknown sponge species from Canton atoll and an unknown sponge Axinella sp., from Belize.
    Type: Grant
    Filed: March 12, 1981
    Date of Patent: January 25, 1983
    Assignee: The Regents of the University of California
    Inventor: D. John Faulkner
  • Patent number: 4350430
    Abstract: A photograph materials processing unit having:a motor drive unit comprising,a base member which has an upper surface, anda drive wheel extending from the upper surface which is in operative relationship to a drive motor, the drive motor also being part of the base.The upper surface of the base member also carries a pair of spaced-apart undriven wheels which are rotatable in planes parallel to the plane of rotation of said drive wheel.The motor drive unit is adapted to carry a cylindrical drum for receiving photographic materials including film and liquid processing chemicals. The drum is carried in 3-point contact on the upper surfaces of the wheels whereby when the drive motor is turned on, the drum rotates on the wheels without substantial longitudinal movement of the drum with respect to the motor drive unit so long as the longitudinal center line of the drum is parallel to the axes of rotation of the wheels.
    Type: Grant
    Filed: January 16, 1981
    Date of Patent: September 21, 1982
    Assignee: Dev Tec Resources, Inc.
    Inventor: Ronald M. Johnson
  • Patent number: 4338300
    Abstract: The method of treating Peyronie's disease which comprises administering an effective amount of the enzyme collagenase directly into the plaques which form in the course of the disease.
    Type: Grant
    Filed: February 5, 1981
    Date of Patent: July 6, 1982
    Assignee: The Regents Of The University Of California
    Inventor: Martin K. Gelbard
  • Patent number: 4336949
    Abstract: A basket for a skipole, consisting of a periphery frame and a connecting piece between the pole and the periphery frame, said piece being an axle located in respect to the skiing direction crosswise, and being asymmetrically fastened to the rear of the said frame, said axle being of rubber or soft plastics called elastomer, and fastened without free play to said frame and said pole thus acting between these as an elastic torsion piece.
    Type: Grant
    Filed: November 12, 1976
    Date of Patent: June 29, 1982
    Inventor: Yrjo Aho
  • Patent number: 4310505
    Abstract: Lipid vesicles comprising a lipid bilayer which includes analogs of cell-surface receptors such as dicetyl phosphate; stearylamine; 6-(5-cholesten-3.beta.-yloxy) hexyl 1-thio-.beta.-L-fucopyranoside; 6-(5-cholesten-3.beta.-yloxy) hexyl 1-thio-.beta.-D-galactopyranoside; 6-(5-cholesten-3.beta.-yloxy)hexyl 1-thio-.alpha.-D-mannopyranoside; 6-(5-cholesten-3-yloxy)hexyl 2-acetamido-2-deoxy-1-thio-.beta.-D-galactopyranoside; 6-(5-cholesten-3.beta.-yloxy)hexyl 6-amino-6-deoxy-1-thio-.beta.-D-galactopyranoside; or 6-(5-cholesten-3.beta.-yloxy)hexyl 6-amino-6-deoxy-1-thio-.alpha.-D-mannopyranoside; cholesterol and distearoyl phospatidylcholine, and an effective amount of physiologically compatible radioactive tracer, cytotoxic or therapeutic agent as a part of the vesicles. The vesicles of this invention can be administered to the human host and have been found to release the contents of the vesicles in a predetermined manner, i.e.
    Type: Grant
    Filed: November 8, 1979
    Date of Patent: January 12, 1982
    Assignee: California Institute of Technology
    Inventors: John D. Baldeschwieler, Ronald C. Gamble, Marcia R. Mauk, Tsung-Ying Shen, Mitree M. Ponpipom
  • Patent number: 4310506
    Abstract: Unilamellar vesicles comprising a lipid bilayer, an ionophore being incorporated in said lipid bilayer, a chelating agent entrapped within the vesicles, and an effective amount of physiologically compatible cation bound to said chelating agent within the vesicles. Unilamellar vesicles are loaded by incubating the vesicles with the cation, terminating the incubation and recovering the loaded vesicles by chromatography. In some applications of the invention, the cation may be a radioactive tracer, in which case the vesicles can be administered to the human host and observed by scintillation techniques to produce a radioimage which is useful for diagnostic purposes.
    Type: Grant
    Filed: February 20, 1980
    Date of Patent: January 12, 1982
    Assignee: California Institute of Technology
    Inventors: John D. Baldeschwieler, Ronald C. Gamble, Marcia R. Mauk
  • Patent number: 4302577
    Abstract: An improved process or method for the preparation of pharmaceutical grade biologically and physiologically "active" chondroitin sulfate, predominantly chondroitin sulfate A, chondroitin sulfate C, and mixtures thereof from source material comprising forming a solution from the source material containing said "active" material, adding thereto a complexing agent to form a precipitate which is a water insoluble complex of the active material and the complexing agent, and breaking said complex to recover the pharmaceutical grade "active" material.
    Type: Grant
    Filed: February 4, 1980
    Date of Patent: November 24, 1981
    Assignee: Biomed Research Inc.
    Inventor: Perry G. Rucker
  • Patent number: 4299812
    Abstract: In the immunoassay of thyroxine using dried blood samples spotted on filter paper, the assay in this invention is run at a pH of 9.2 to 10.0, preferably at about 9.5, rather than the pH range of about 8.4 to 8.7 generally used in the art. The advantage of this higher pH range is that more accurate results are obtained with neonatal specimens. An additional advantage is that the blank or nonspecific binding is lower for many immunoassay procedures.
    Type: Grant
    Filed: November 29, 1978
    Date of Patent: November 10, 1981
    Assignee: Diagnostic Products Corp.
    Inventor: Robert F. Coombes
  • Patent number: 4296747
    Abstract: A device for introducing fluid into urethral catheters having a free end fitment and/or a pierceable injection site comprising a syringe structure actuable to expel fluid from an outlet at one end thereof, and a connector structure extending from the one end of the syringe structure and defining an axial fluid passage communicating with the outlet. The connector structure is provided with a first axially tapered surface portion receivable in sealing relationship within the free end fitments of urethral catheters, and a second axially tapered surface portion engageable in sealing relationship with a luer needle fitment. Fluid from the syringe structure is introduced into the catheters either through a free end fitment or an injection site for passage toward the urethra.
    Type: Grant
    Filed: February 11, 1980
    Date of Patent: October 27, 1981
    Assignee: IMS Limited
    Inventor: Robert W. Ogle
  • Patent number: 4293778
    Abstract: A partially conductive security screen arrangement for use with an intrusion alarm system designed to operate in a normally closed sensing circuit condition and to produce a warning signal when the sensing circuit is broken, which arrangement includes conductive means overlying and bonded to a mesh screen positionable to cover an opening in a building. The conductive means is connectible at its two ends to the sensing circuit in a series relationship with the remainder of that circuit. The conductive means is positioned on the screen in a configuration preventing passage of a human being through the screen unless the conductive means is severed. Passage of a human being through the opening while the screen is in position to cover the opening therefore breaks the sensing circuit to produce a warning signal.
    Type: Grant
    Filed: February 12, 1979
    Date of Patent: October 6, 1981
    Assignee: Sandstone, Inc.
    Inventor: William H. Williams
  • Patent number: 4286389
    Abstract: Apparatus for use in lyophilizing a substance in a container and sealing the substance within the container after lyophilization. The apparatus includes an upper portion positionable about a resilient stopper in frictional engagement therewith, and a structure supporting the upper portion. The supporting structure is positionable on the open end of the container to space the upper portion and the stopper axially therefrom and define at least one fluid path communicating with the interior of the container. The upper portion and the supporting means may define an axial passageway for conducting the stopper from the initial position to a sealing position at least partially within the open end of the container upon application of an axial force to the stopper.
    Type: Grant
    Filed: March 3, 1980
    Date of Patent: September 1, 1981
    Assignee: IMS Limited
    Inventor: Robert W. Ogle
  • Patent number: 4259956
    Abstract: This patent describes a novel medicament package particularly adapted for the containment of liquid medication comprising a shell vial having cylindrical walls and an open end and a closed end, within said vial an inwardly extending annular shoulder integral with said cylindrical walls of said vial, said shoulder forming an annular indentation on the exterior of the wall of said vial, said cylindrical walls extending from said shoulder to said open and closed end, said shoulder being in proximity to the open end of said vial, an imperforate resilient stopper sealing the closed end of said vial, the peripheral portion of that side of the stopper facing the open end of the vial forming a seal on the inner surface of said shoulder to prevent the outward movement of said stopper within said vial under the influence of the vapor pressure of said liquid medication, said stopper being adapted to reciprocate in a piston-like fashion to the closed end of said vial to expel the contents thereof through a hollow needle
    Type: Grant
    Filed: September 21, 1976
    Date of Patent: April 7, 1981
    Assignee: IMS Limited
    Inventor: Robert W. Ogle
  • Patent number: 4253501
    Abstract: A transfer device for withdrawal of aliquots from a container of bulk solution is provided with a body having a tapered chamber, a first passage venting the smaller end of the chamber to the surrounding air, a second passage communicating at one end with the larger end of the chamber, and a third passage having one end for withdrawal of fluid therefrom. A tapered valve element is received within the chamber for movement between first and second conditions in response to changes in the presence differential between the first and second passages. The first condition provides a fluid seal between the first and second passages by engagement of the valve element with the walls of the chamber for pressures within the second passage greater than that within the first passage, and the second condition provides a fluid path from the first passage to the second passage for pressures within the second passage somewhat less than that within the first passage.
    Type: Grant
    Filed: November 9, 1979
    Date of Patent: March 3, 1981
    Assignee: IMS Limited
    Inventor: Robert W. Ogle
  • Patent number: 4252769
    Abstract: An improved apparatus for the performance of chemical processes having a reaction chamber with an open end, a reaction cell mounted within the chamber and having a substantially cylindrical interior wall in which is formed an annular groove, and means for spinning the cell about its axis to distribute a chemical compound on the interior wall as a thin film, which includes a closure member mounted for rotation about an axis displaced from the axis of the cell, and a fluid conduit extending through the closure member and terminating at an inner end within the cell for the withdrawal of fluid therefrom. The inner end of the conduit is displaced from the axis of rotation of the closure member and is positioned substantially opposite the annular groove such that it is actuable for adjustment between a first location displaced radially from the annular groove and a second location substantially within the groove by rotation of the closure member through a preselected angle.
    Type: Grant
    Filed: December 26, 1979
    Date of Patent: February 24, 1981
    Assignee: California Institute of Technology
    Inventors: Leroy E. Hood, Michael W. Hunkapiller
  • Patent number: D263254
    Type: Grant
    Filed: August 27, 1979
    Date of Patent: March 2, 1982
    Assignee: IMS Limited
    Inventor: Robert W. Ogle