Patents Represented by Attorney Joseph I. Hirsch
  • Patent number: 7964189
    Abstract: The present invention relates to nutritional supplements to be administered to, or to be taken by, women desiring to become pregnant, and pregnant and nursing women. The nutritional supplements of this invention have a unique blend of vitamins, minerals, lycopene, co-enzyme Q10, DHA, docusate (such as docusate sodium), folic acid, and a nutritionally acceptable carrier therefor. The invention includes specific nutritional supplements for the uses set forth above.
    Type: Grant
    Filed: September 19, 2008
    Date of Patent: June 21, 2011
    Assignee: Argent Development Group, LLC
    Inventors: John C. Morrison, Kenneth R. Greathouse
  • Patent number: 4542237
    Abstract: .alpha.-Arylalkanoic acids or esters, orthoesters or amides thereof are prepared by forming an .alpha.-hydroxy ketal or thioketal of an aryl alkyl ketone, activating the .alpha.-hydroxy substituent with an esterifying agent to form the corresponding ketal or thioketal ester substrate, wherein the ester group is sufficiently labile to non-catalytically disassociate from the substrate in a protic or dipolar, aprotic solvent, maintaining the ester substrate in contact with the protic or dipolar, aprotic solvent or mixtures thereof for a time sufficient to form the corresponding .alpha.-arylakanoic acid or ester, orthoester or amide thereof, and optionally concomitantly or sequentially hydrolyzing any ester, orthoester or amide formed to the corresponding .alpha.-arylalkanoic acid.
    Type: Grant
    Filed: June 7, 1983
    Date of Patent: September 17, 1985
    Assignee: Syntex Pharmaceuticals International Limited
    Inventor: George C. Schloemer
  • Patent number: 4539420
    Abstract: A manufacturing method is described for the preparation of optically active 1-aromatic-group-substituted-1-alkanones characterized in that an optically active alkane acid halide is allowed to react with an aromatic compound in the presence of a Lewis acid. The optically active 1-aromatic-group-substituted-1-alkanones are useful intermediates in the preparation of optically active alpha-arylalkanoic acids, which are useful as pharmaceutical, e.g. anti-inflammatory, analgesic and anti-pyretic, agents and as insecticidal agents.
    Type: Grant
    Filed: June 11, 1982
    Date of Patent: September 3, 1985
    Assignee: Syntex Pharmaceuticals International Limited
    Inventors: Gen-Ichi Tsuchihashi, Shuichi Mitamura, Koji Kitajima
  • Patent number: 4515811
    Abstract: Mixtures of d 2-(6-methoxy-2-naphthyl)propionic acid and 1 2-(6-methoxy-2-naphthyl)propionic acid or soluble salts thereof are resolved with N-R-D-glucamine or salts thereof, where R is alkyl having 2 to 36 carbon atoms or cycloalkyl having 3 to 8 carbon atoms, to yield a product substantially enriched in d 2-(6-methoxy-2-naphthyl)propionic acid.
    Type: Grant
    Filed: June 4, 1980
    Date of Patent: May 7, 1985
    Assignee: Syntex Corporation
    Inventor: Percy G. Holton
  • Patent number: 4474572
    Abstract: An implanting device for implanting pellets and like subcutaneously or intramuscularly in animals is described which utilizes means for indexing an implant magazine having a plurality of pellet-containing stations therein and means for automatically retracting a needle from about an implant charge to deposit the pellets in an animal. The implant magazine is indexed for sequential applications automatically as the retraction mechanism is cocked. Additionally, means for automatically ejecting a spent or empty implant cartridge are provided to prevent false deposition of implants. An implant cartridge having open channels containing implants can be utilized with the implanting device, the channels having means thereon for increasing the size of the channel during the implanting step to substantially eliminate the crushing or breaking of pellets as they are expelled from the cartridge. Alignment and stabilization means for the implant magazine and the implanting device also are provided.
    Type: Grant
    Filed: May 5, 1983
    Date of Patent: October 2, 1984
    Assignee: Syntex (U.S.A.) Inc.
    Inventors: Allen D. McNaughton, Stephen B. Albert, Gerard A. Furbershaw
  • Patent number: 4414127
    Abstract: Disclosed herein are aqueous solutions for cleaning contact lenses comprising a water-soluble peroxide, transition metal salts, an amphoteric or anionic surfactant, and, optionally, tonicity salts.
    Type: Grant
    Filed: July 6, 1981
    Date of Patent: November 8, 1983
    Assignee: Syntex (U.S.A.) Inc.
    Inventor: Cherng-Chyi Fu
  • Patent number: 4403989
    Abstract: An injection device particularly suitable for the intraruminal injection of ruminants is described. The injection device is characterized by a needle carrying means and a needle actuation means, which are operatively coupled such that the needle actuation means permits movement of the needle carrying means from a retracted position to an extended position, wherein the needle is capable of piercing the rumen, only when the needle carrying means is in a preferred orientation (e.g. perpendicular) to the surface of the host animal at the injection site. The injection device is further characterized by a dose delivery actuation means which is responsive to the relative position of the needle carrying means and the needle actuation means such that the dose is delivered to the host animal only when the needle carrying means and the needle actuation means are in a preferred position relative to each other.
    Type: Grant
    Filed: September 14, 1981
    Date of Patent: September 13, 1983
    Assignee: Syntex (U.S.A.) Inc.
    Inventors: Terrence B. Christensen, Allen D. McNaughton, Steven R. Umbach
  • Patent number: 4401372
    Abstract: This invention concerns a minus prescription hydrogel contact lens that permits oxygen diffusion to the cornea in sufficient quantity to avoid the effects of oxygen deprivation; avoids the physiological complications arising from damage to the bulbar conjunctivia due to compression of the limbal capillaries; and avoids corneal scleral or wetting deficiencies. These advantages are accomplished through a combination of lens design and hydrogel properties.
    Type: Grant
    Filed: December 10, 1979
    Date of Patent: August 30, 1983
    Assignee: Syntex (U.S.A.) Inc.
    Inventors: William L. Mancini, Donald R. Korb, Miguel F. Refojo
  • Patent number: 4401797
    Abstract: Copolymers having improved machining and water resistant properties are produced using a monomer containing an adduct protecting group, particularly an alkyl boronic acid adduct, of glyceryl acrylate or glyceryl methacrylate, in combination with an alkyl acrylate or methacrylate, and optionally a glycidyl acrylate or methacrylate. After machining and shaping, the adduct is removed to provide a hydrogel useful as a contact lens material.
    Type: Grant
    Filed: May 20, 1981
    Date of Patent: August 30, 1983
    Assignee: Syntex (U.S.A.) Inc.
    Inventor: Paul M. Gallop
  • Patent number: 4400170
    Abstract: An implanting device for implanting pellets and like subcutaneously or intramuscularly in animals is described which utilizes means for indexing an implant magazine having a plurality of pellet-containing stations therein and means for automatically retracting a needle from about an implant charge to deposit the pellets in an animal. The implant magazine is indexed for sequential applications automatically as the retraction mechanism is cocked. Additionally, means for automatically ejecting a spent or empty implant cartridge are provided to prevent false deposition of implants. An implant cartridge having open channels containing implants can be utilized with the implanting device, the channels having means thereon for increasing the size of the channel during the implanting step to substantially eliminate the crushing or breaking of pellets as they are expelled from the cartridge. Alignment and stabilization means for the implant magazine and the implanting device also are provided.
    Type: Grant
    Filed: September 29, 1981
    Date of Patent: August 23, 1983
    Assignee: Syntex (U.S.A.) Inc.
    Inventors: Allen D. McNaughton, Stephen B. Albert, Gerard A. Furbershaw
  • Patent number: 4397439
    Abstract: A fluid actuated brake assembly for use with a parallelogram linkage on a dental tray support arm is described. Floating brake shoes positioned on opposite sides of one member of the parallelogram linkage with one of the brake shoes pivotably and slideably attached to the other member of the parallelogram linkage provides a braking and locking effect between the two members of the parallelogram linkage to provide an efficient brake for a dental tray support arm. Upon fluid actuation of the brake assembly, the brake shoes grip one member of the parallelogram and form a rigid connection with the other member of the parallelogram to prevent relative movement of the parallelogram linkage members. The frictional brake assembly also provides an override feature above a predetermined force level to prevent accidental jamming of the dental tray support arm against an object.
    Type: Grant
    Filed: February 13, 1981
    Date of Patent: August 9, 1983
    Assignee: Syntex (U.S.A.) Inc.
    Inventors: Lawrence A. Wilbur, Stanley E. Gordon
  • Patent number: 4389220
    Abstract: A method of conditioning diesel engines is described. In accordance with the method, a diesel engine is operated on a diesel fuel containing from about 20-30 ppm of dicyclopentadienyl iron or an equivalent amount of a derivative thereof for a period of time sufficient to eliminate carbon deposits from the combustion surfaces of the engine and to deposit a layer of iron oxide on the combustion surfaces, which layer is effective to prevent further buildup of carbon deposits, and subsequently the diesel engine is operated on a maintenance concentration of from about 10-15 ppm of dicyclopentadienyl iron or an equivalent amount of a derivative thereof on a continuous basis. The maintenance concentration is effective to maintain the catalytic iron oxide layer on the combustion surfaces but insufficient to decrease timing delay in the engine.
    Type: Grant
    Filed: June 4, 1980
    Date of Patent: June 21, 1983
    Assignee: Syntex (U.S.A.) Inc.
    Inventor: John J. Kracklauer
  • Patent number: 4388229
    Abstract: A solution for removing occluded and adsorbed chemicals, such as cationic preservating agents, anionic preserving agents and mixtures thereof, from contact lenses which comprises a nonionic surfactant; a cationic ion exchange resin, an anionic ion exchange resin, or mixtures thereof; water; and optionally sodium chloride. Such solutions are useful to reduce and prevent irritation of the eye of the contact lens wearer.
    Type: Grant
    Filed: November 2, 1981
    Date of Patent: June 14, 1983
    Assignee: Syntex (U.S.A.) Inc.
    Inventor: Cherng-Chyi Fu
  • Patent number: 4379864
    Abstract: The invention provides new hydrogel forming materials comprising synthetic, hydrophilic, aqueous-insoluble polymer networks formed by copolymerization of a hydrophilic dihydroxyalkyl acrylate or methacrylate, a substantially water insoluble alkyl acrylate or methacrylate, one or more additional hydrophilic comonomers selected from the group of vinylic monomers, acrylates, and methacrylates, and a cross-linking agent. The hydrogels are preferably used for the formation of contact lenses, but may also be used for drug and pesticides delivery devices; dialysis, ultrafiltration and reverse osmosis membranes; implants in surgery and dentistry; and the like.
    Type: Grant
    Filed: March 5, 1981
    Date of Patent: April 12, 1983
    Assignee: Syntex (U.S.A.) Inc.
    Inventors: Paul M. Gallop, Donald R. Korb
  • Patent number: 4375964
    Abstract: A dental instrument is disclosed having a light source assembly suspension which includes resilient means, such as a coil spring, for supporting the lamp assembly while at the same time reducing vibration that may be transmitted from the instrument to the light source assembly. The resilient means also reduces heat loss from the light source assembly to the dental instrument so that shorter filament warm-up time is provided. The light source assembly suspension is particularly useful in a dental handpiece in which the frequency of vibration of the gas-driven motor may coincide with one of the harmonic frequencies of vibration of the lamp filament or filament support.
    Type: Grant
    Filed: November 3, 1980
    Date of Patent: March 8, 1983
    Assignee: Syntex (U.S.A.) Inc.
    Inventors: Arthur A. Knopp, Leonard J. Kelly
  • Patent number: 4360281
    Abstract: A reversible cam lock assembly is described. The cam lock assembly is adapted for attachment to a movable member and includes an eccentric cam for engaging a surface of a stationary member to resist movement inducing forces applied to the movable member. Depending on the orientation of the cam lock assembly, clockwise or counterclockwise rotational movement of the movable member relative to the stationary member is resisted.
    Type: Grant
    Filed: July 24, 1980
    Date of Patent: November 23, 1982
    Assignee: Syntex (U.S.A.) Inc.
    Inventors: J. Douglas Alsup, Jr., Arden F. Jenkins
  • Patent number: 4341881
    Abstract: Flexible polyvinyl chloride having improved flame retardancy and reduced smoke generating properties. The plastics are characterized in that they contain about from 0.01 to 0.2 parts, by wt., based on the iron content, of a high molecular weight ferrocene derivative and about 0.1 to 20 parts, by wt., of antimony oxide per 100 parts of polyvinyl chloride resin. A composition comprising the ferrocene derivative and antimony oxide useful for preparing the improved plastic is also disclosed.
    Type: Grant
    Filed: April 19, 1979
    Date of Patent: July 27, 1982
    Assignee: Syntex (U.S.A.) Inc.
    Inventors: John J. Kracklauer, Charles J. Sparkes
  • Patent number: D266109
    Type: Grant
    Filed: December 10, 1979
    Date of Patent: September 7, 1982
    Assignee: Syntex (U.S.A.) Inc.
    Inventors: Anthony T. Sertich, N. Dominic Marucci
  • Patent number: D268149
    Type: Grant
    Filed: December 29, 1980
    Date of Patent: March 8, 1983
    Assignee: Syntex (U.S.A.) Inc.
    Inventor: Robert Case
  • Patent number: RE31406
    Abstract: Contact lenses are fabricated from a copolymer of a polysiloxanylalkyl acrylic ester and an alkyl acrylic ester. The copolymer has increased oxygen permeability.
    Type: Grant
    Filed: December 11, 1980
    Date of Patent: October 4, 1983
    Assignee: Syntex (U.S.A.) Inc.
    Inventor: Norman G. Gaylord