Patents Represented by Attorney Joseph I. Hirsch
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Patent number: 7964189Abstract: The present invention relates to nutritional supplements to be administered to, or to be taken by, women desiring to become pregnant, and pregnant and nursing women. The nutritional supplements of this invention have a unique blend of vitamins, minerals, lycopene, co-enzyme Q10, DHA, docusate (such as docusate sodium), folic acid, and a nutritionally acceptable carrier therefor. The invention includes specific nutritional supplements for the uses set forth above.Type: GrantFiled: September 19, 2008Date of Patent: June 21, 2011Assignee: Argent Development Group, LLCInventors: John C. Morrison, Kenneth R. Greathouse
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Patent number: 4542237Abstract: .alpha.-Arylalkanoic acids or esters, orthoesters or amides thereof are prepared by forming an .alpha.-hydroxy ketal or thioketal of an aryl alkyl ketone, activating the .alpha.-hydroxy substituent with an esterifying agent to form the corresponding ketal or thioketal ester substrate, wherein the ester group is sufficiently labile to non-catalytically disassociate from the substrate in a protic or dipolar, aprotic solvent, maintaining the ester substrate in contact with the protic or dipolar, aprotic solvent or mixtures thereof for a time sufficient to form the corresponding .alpha.-arylakanoic acid or ester, orthoester or amide thereof, and optionally concomitantly or sequentially hydrolyzing any ester, orthoester or amide formed to the corresponding .alpha.-arylalkanoic acid.Type: GrantFiled: June 7, 1983Date of Patent: September 17, 1985Assignee: Syntex Pharmaceuticals International LimitedInventor: George C. Schloemer
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Patent number: 4539420Abstract: A manufacturing method is described for the preparation of optically active 1-aromatic-group-substituted-1-alkanones characterized in that an optically active alkane acid halide is allowed to react with an aromatic compound in the presence of a Lewis acid. The optically active 1-aromatic-group-substituted-1-alkanones are useful intermediates in the preparation of optically active alpha-arylalkanoic acids, which are useful as pharmaceutical, e.g. anti-inflammatory, analgesic and anti-pyretic, agents and as insecticidal agents.Type: GrantFiled: June 11, 1982Date of Patent: September 3, 1985Assignee: Syntex Pharmaceuticals International LimitedInventors: Gen-Ichi Tsuchihashi, Shuichi Mitamura, Koji Kitajima
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Patent number: 4515811Abstract: Mixtures of d 2-(6-methoxy-2-naphthyl)propionic acid and 1 2-(6-methoxy-2-naphthyl)propionic acid or soluble salts thereof are resolved with N-R-D-glucamine or salts thereof, where R is alkyl having 2 to 36 carbon atoms or cycloalkyl having 3 to 8 carbon atoms, to yield a product substantially enriched in d 2-(6-methoxy-2-naphthyl)propionic acid.Type: GrantFiled: June 4, 1980Date of Patent: May 7, 1985Assignee: Syntex CorporationInventor: Percy G. Holton
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Patent number: 4474572Abstract: An implanting device for implanting pellets and like subcutaneously or intramuscularly in animals is described which utilizes means for indexing an implant magazine having a plurality of pellet-containing stations therein and means for automatically retracting a needle from about an implant charge to deposit the pellets in an animal. The implant magazine is indexed for sequential applications automatically as the retraction mechanism is cocked. Additionally, means for automatically ejecting a spent or empty implant cartridge are provided to prevent false deposition of implants. An implant cartridge having open channels containing implants can be utilized with the implanting device, the channels having means thereon for increasing the size of the channel during the implanting step to substantially eliminate the crushing or breaking of pellets as they are expelled from the cartridge. Alignment and stabilization means for the implant magazine and the implanting device also are provided.Type: GrantFiled: May 5, 1983Date of Patent: October 2, 1984Assignee: Syntex (U.S.A.) Inc.Inventors: Allen D. McNaughton, Stephen B. Albert, Gerard A. Furbershaw
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Patent number: 4414127Abstract: Disclosed herein are aqueous solutions for cleaning contact lenses comprising a water-soluble peroxide, transition metal salts, an amphoteric or anionic surfactant, and, optionally, tonicity salts.Type: GrantFiled: July 6, 1981Date of Patent: November 8, 1983Assignee: Syntex (U.S.A.) Inc.Inventor: Cherng-Chyi Fu
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Patent number: 4403989Abstract: An injection device particularly suitable for the intraruminal injection of ruminants is described. The injection device is characterized by a needle carrying means and a needle actuation means, which are operatively coupled such that the needle actuation means permits movement of the needle carrying means from a retracted position to an extended position, wherein the needle is capable of piercing the rumen, only when the needle carrying means is in a preferred orientation (e.g. perpendicular) to the surface of the host animal at the injection site. The injection device is further characterized by a dose delivery actuation means which is responsive to the relative position of the needle carrying means and the needle actuation means such that the dose is delivered to the host animal only when the needle carrying means and the needle actuation means are in a preferred position relative to each other.Type: GrantFiled: September 14, 1981Date of Patent: September 13, 1983Assignee: Syntex (U.S.A.) Inc.Inventors: Terrence B. Christensen, Allen D. McNaughton, Steven R. Umbach
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Patent number: 4401797Abstract: Copolymers having improved machining and water resistant properties are produced using a monomer containing an adduct protecting group, particularly an alkyl boronic acid adduct, of glyceryl acrylate or glyceryl methacrylate, in combination with an alkyl acrylate or methacrylate, and optionally a glycidyl acrylate or methacrylate. After machining and shaping, the adduct is removed to provide a hydrogel useful as a contact lens material.Type: GrantFiled: May 20, 1981Date of Patent: August 30, 1983Assignee: Syntex (U.S.A.) Inc.Inventor: Paul M. Gallop
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Patent number: 4401372Abstract: This invention concerns a minus prescription hydrogel contact lens that permits oxygen diffusion to the cornea in sufficient quantity to avoid the effects of oxygen deprivation; avoids the physiological complications arising from damage to the bulbar conjunctivia due to compression of the limbal capillaries; and avoids corneal scleral or wetting deficiencies. These advantages are accomplished through a combination of lens design and hydrogel properties.Type: GrantFiled: December 10, 1979Date of Patent: August 30, 1983Assignee: Syntex (U.S.A.) Inc.Inventors: William L. Mancini, Donald R. Korb, Miguel F. Refojo
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Patent number: 4400170Abstract: An implanting device for implanting pellets and like subcutaneously or intramuscularly in animals is described which utilizes means for indexing an implant magazine having a plurality of pellet-containing stations therein and means for automatically retracting a needle from about an implant charge to deposit the pellets in an animal. The implant magazine is indexed for sequential applications automatically as the retraction mechanism is cocked. Additionally, means for automatically ejecting a spent or empty implant cartridge are provided to prevent false deposition of implants. An implant cartridge having open channels containing implants can be utilized with the implanting device, the channels having means thereon for increasing the size of the channel during the implanting step to substantially eliminate the crushing or breaking of pellets as they are expelled from the cartridge. Alignment and stabilization means for the implant magazine and the implanting device also are provided.Type: GrantFiled: September 29, 1981Date of Patent: August 23, 1983Assignee: Syntex (U.S.A.) Inc.Inventors: Allen D. McNaughton, Stephen B. Albert, Gerard A. Furbershaw
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Patent number: 4397439Abstract: A fluid actuated brake assembly for use with a parallelogram linkage on a dental tray support arm is described. Floating brake shoes positioned on opposite sides of one member of the parallelogram linkage with one of the brake shoes pivotably and slideably attached to the other member of the parallelogram linkage provides a braking and locking effect between the two members of the parallelogram linkage to provide an efficient brake for a dental tray support arm. Upon fluid actuation of the brake assembly, the brake shoes grip one member of the parallelogram and form a rigid connection with the other member of the parallelogram to prevent relative movement of the parallelogram linkage members. The frictional brake assembly also provides an override feature above a predetermined force level to prevent accidental jamming of the dental tray support arm against an object.Type: GrantFiled: February 13, 1981Date of Patent: August 9, 1983Assignee: Syntex (U.S.A.) Inc.Inventors: Lawrence A. Wilbur, Stanley E. Gordon
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Patent number: 4389220Abstract: A method of conditioning diesel engines is described. In accordance with the method, a diesel engine is operated on a diesel fuel containing from about 20-30 ppm of dicyclopentadienyl iron or an equivalent amount of a derivative thereof for a period of time sufficient to eliminate carbon deposits from the combustion surfaces of the engine and to deposit a layer of iron oxide on the combustion surfaces, which layer is effective to prevent further buildup of carbon deposits, and subsequently the diesel engine is operated on a maintenance concentration of from about 10-15 ppm of dicyclopentadienyl iron or an equivalent amount of a derivative thereof on a continuous basis. The maintenance concentration is effective to maintain the catalytic iron oxide layer on the combustion surfaces but insufficient to decrease timing delay in the engine.Type: GrantFiled: June 4, 1980Date of Patent: June 21, 1983Assignee: Syntex (U.S.A.) Inc.Inventor: John J. Kracklauer
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Patent number: 4388229Abstract: A solution for removing occluded and adsorbed chemicals, such as cationic preservating agents, anionic preserving agents and mixtures thereof, from contact lenses which comprises a nonionic surfactant; a cationic ion exchange resin, an anionic ion exchange resin, or mixtures thereof; water; and optionally sodium chloride. Such solutions are useful to reduce and prevent irritation of the eye of the contact lens wearer.Type: GrantFiled: November 2, 1981Date of Patent: June 14, 1983Assignee: Syntex (U.S.A.) Inc.Inventor: Cherng-Chyi Fu
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Patent number: 4379864Abstract: The invention provides new hydrogel forming materials comprising synthetic, hydrophilic, aqueous-insoluble polymer networks formed by copolymerization of a hydrophilic dihydroxyalkyl acrylate or methacrylate, a substantially water insoluble alkyl acrylate or methacrylate, one or more additional hydrophilic comonomers selected from the group of vinylic monomers, acrylates, and methacrylates, and a cross-linking agent. The hydrogels are preferably used for the formation of contact lenses, but may also be used for drug and pesticides delivery devices; dialysis, ultrafiltration and reverse osmosis membranes; implants in surgery and dentistry; and the like.Type: GrantFiled: March 5, 1981Date of Patent: April 12, 1983Assignee: Syntex (U.S.A.) Inc.Inventors: Paul M. Gallop, Donald R. Korb
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Patent number: 4375964Abstract: A dental instrument is disclosed having a light source assembly suspension which includes resilient means, such as a coil spring, for supporting the lamp assembly while at the same time reducing vibration that may be transmitted from the instrument to the light source assembly. The resilient means also reduces heat loss from the light source assembly to the dental instrument so that shorter filament warm-up time is provided. The light source assembly suspension is particularly useful in a dental handpiece in which the frequency of vibration of the gas-driven motor may coincide with one of the harmonic frequencies of vibration of the lamp filament or filament support.Type: GrantFiled: November 3, 1980Date of Patent: March 8, 1983Assignee: Syntex (U.S.A.) Inc.Inventors: Arthur A. Knopp, Leonard J. Kelly
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Patent number: 4360281Abstract: A reversible cam lock assembly is described. The cam lock assembly is adapted for attachment to a movable member and includes an eccentric cam for engaging a surface of a stationary member to resist movement inducing forces applied to the movable member. Depending on the orientation of the cam lock assembly, clockwise or counterclockwise rotational movement of the movable member relative to the stationary member is resisted.Type: GrantFiled: July 24, 1980Date of Patent: November 23, 1982Assignee: Syntex (U.S.A.) Inc.Inventors: J. Douglas Alsup, Jr., Arden F. Jenkins
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Patent number: 4341881Abstract: Flexible polyvinyl chloride having improved flame retardancy and reduced smoke generating properties. The plastics are characterized in that they contain about from 0.01 to 0.2 parts, by wt., based on the iron content, of a high molecular weight ferrocene derivative and about 0.1 to 20 parts, by wt., of antimony oxide per 100 parts of polyvinyl chloride resin. A composition comprising the ferrocene derivative and antimony oxide useful for preparing the improved plastic is also disclosed.Type: GrantFiled: April 19, 1979Date of Patent: July 27, 1982Assignee: Syntex (U.S.A.) Inc.Inventors: John J. Kracklauer, Charles J. Sparkes
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Patent number: D266109Type: GrantFiled: December 10, 1979Date of Patent: September 7, 1982Assignee: Syntex (U.S.A.) Inc.Inventors: Anthony T. Sertich, N. Dominic Marucci
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Patent number: D268149Type: GrantFiled: December 29, 1980Date of Patent: March 8, 1983Assignee: Syntex (U.S.A.) Inc.Inventor: Robert Case
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Patent number: RE31406Abstract: Contact lenses are fabricated from a copolymer of a polysiloxanylalkyl acrylic ester and an alkyl acrylic ester. The copolymer has increased oxygen permeability.Type: GrantFiled: December 11, 1980Date of Patent: October 4, 1983Assignee: Syntex (U.S.A.) Inc.Inventor: Norman G. Gaylord