Abstract: The invention relates to novel cyclopenteno[b]pyridine derivatives which have a group X on the 7-position and related tricyclic compounds. X is CONHR.sup.3, or CO.sub.2 R.sup.5 wherein R.sup.3 is hydrogen or lower alkyl and R.sup.5 is hydrogen or a lower alkyl or lower aralkyl group which may be substituted by alkyl, alkoxy, halogen, nitro or trifluoromethyl; other substituents may be present. The compounds are intermediates for compounds wherein X is CSNHR.sup.3 which are anti-ulcer agents.

Abstract: It has been found that compounds having a stereochemically unencumbered access to a nitrogen-nitrogen bond have antiviral activity in extremely low dose ranges. Hydrazine, hydrazine derivatives and related compounds have been found to be active in protecting animals against disease caused by both DNA and RNA type viruses at doses of about 250 picograms to 250 micrograms per kilogram of host body weight.

Abstract: An electrical shocking device includes a manipulatable, preferably tubular, housing, one end of which is open and provided with a flange. A plastic tube is movably positioned within the housing against the flange. The plastic tube contains an electric circuit, including a spark gap and circuit members for converting a low direct voltage into a very high voltage, storing a high voltage charge and intermittently discharging the storage device. A pair of probes extend outwardly from the tube beyond the flange, those ends of the probes within the tube being connected to opposite ends of a charge-storing capacitor through a spark gap in series with one of the probes. Batteries and a switch are provided within the housing for supplying the low direct voltage to the circuit upon movement of the tube in response to force on the probes.

Abstract: The disclosure is directed to the combination of a container for dispensing liquid from an inverted position and a hanger device for suspending the container in an inverted position from the wall of a water closet. The hanger device consists of a planar member connected to a flanged cylindrical shaft eccentrically of the center of rotation of the shaft and opposite the flanged end. Recesses are defined in the side wall of the container to retain the shaft and in the end wall of the container to receive the planar member. The planar member and shaft swivel so that the planar member may be moved from a position where it is substantially flush with the container out to a position where it will engage the top of a wall of a water closet. The length of the shaft and the size of the recesses relative to one another may be such that the hanger device merely rotates in the recesses or such that the hanger device both rotates and reciprocates in the recesses.

Abstract: A new process for preparing 5-oxo-tetrahydroquinolines comprises condensing a compound of formula II with a ##STR1## compound of formula III to obtain a compound of formula I wherein R, R.sup.1, R.sup.2 and R.sup.3 are selected from hydrogen or alkyl, aralkyl or aryl groups, Y is NH.sub.2 or OH accompanied by an ethylenic bond or Y is oxo and the double bond is absent and A is an amino or lower alkoxy group of 1-4 carbon atoms at least one of Y or A being amino. Compounds of formula I are intermediates for pharmaceuticals.

Abstract: A sealed dispensing container for liquid medicaments is described which may be readily opened by a twisting force applied on opposite ends of the container. All of the parts of the container making up a chamber for the medicament are shaped to be substantially completely flattened by the application of a compressive force, such as that applied by thumb and forefinger, to completely discharge the liquid medicament. After the container is opened, the liquid will be retained in the container in the absence of a compressive force and regardless of the orientation of the container in a horizontal or inverted position.

Abstract: The formation of hydrates of anhydrous ampicillin in aqueous suspension may be retarded or entirely prevented for extended periods by (1) the addition of about 70 to 86% w/v of sucrose and (2) adjustment of the product pH to about 5.0 to 6.5. The invention is useful in extending the shelf life of aqueous dosage forms of anhydrous ampicillin.

Abstract: The disclosure is directed to 1,6-bis-(substituted oxy)-xanthen-9-ones which have the formula ##SPC1##Where R.sub.1 is morpholino(lower)alkyl, di(lower)alkylamino(lower)-alkyl, or pyrrolidinyl(lower)alkyl; and R.sub.2 is lower alkylamino (lower)alkyl or hydrogen. The compounds are active as immunoregulators or as intermediates in the preparation of immunoregulators. The intermediates also have trichomonacidal activity.

Abstract: It has been found that compounds having a stereochemically unencumbered access to a nitrogen-nitrogen bond have antiviral activity in extremely low dose ranges. Hydrazine, hydrazine derivatives and related compounds have been found to be active in protecting animals against disease caused by both DNA and RNA type viruses at doses of about 250 picograms to 250 micrograms per kilogram of host body weight.

Abstract: The disclosure is directed to apparatus for inverting ferromagnetic containers so that foreign matter contained in them may fall free or be blown free while they are in the inverted position. The containers are then returned to the upright position and transferred to further operating stations.

Abstract: A method for transferring a coverslip from one location to another comprises placing a suction pad on to one surface of the coverslip, applying suction to the suction pad so that the coverslip adheres temporarily to the suction pad and transferring the suction pad with the adhering coverslip from a first location to a second location. The invention also provides a specific apparatus for carrying out the method. Also provided is an apparatus for feeding coverslips singly from a stack of coverslips employing an open bottomed hopper for the stack of coverslips which rests on a plate having a depression, to accommodate a single coverslip, in its upper surface. The invention further provides a substantially automatic apparatus for placing mounting medium and coverslips on to microscope slides which apparatus can include the apparatus for transferring coverslips and the apparatus for feeding coverslips singly from a stack of coverslips.

Abstract: The disclosure is directed to an improved popcorn package made of a metal foil pan closed by an expansible, clear plastic cover, and an annular gasket disposed adjacent the cover. The gasket has a plurality of fingers adhesively connected to the expansible plastic cover and adapted to support it during expansion.

Abstract: The disclosure is directed to a container for unit doses of dry vaccines which are to be administered on the surface of the skin. The unit dose container is made up of a rigid receptacle and a compressible closure which supports a bifurcated needle bearing dried vaccine. The closure is adapted to support the needle in the container during a lyophilizing process while liquid vaccine is dried on the needle. The closure has grooves which in one position of the closure relative to the receptacle permit the vaporized liquid from the vaccine to be withdrawn from the receptacle during lyophilizing. In another position the closure seals the container. The move from the first position to the second position is accomplished merely by pressing on the end of the closure.

Abstract: The invention is directed to 4-amino-2-phenyl-6-thiopyrimidine compounds having the formula ##SPC1##Where R.sup.1 -R.sup.3 are as defined in the specification. The compounds have pharmacodynamic activity as central nervous system depressants. That is, they produce a calming effect in the host.

Abstract: The disclosure is directed to formulations for tablets which are to be deeply grooved to facilitate breaking into predetermined portions by the user. A critical tablet weight for deeply grooved tablets is disclosed.

Abstract: The disclosure is directed to formulations for tablets which are to be deeply grooved to facilitate breaking into predetermined portions by the user. A critical tablet weight for deeply grooved tablets is disclosed.