Patents Represented by Attorney K. J. Dow

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  • Urethanes and ureas that induce cytokine production
    Patent number: 5312831
    Abstract: The invention relates to novel ureas and urethanes of Formula I: ##STR1## which stimulate cytokine production and may be used to accelerate recovery from neutropenia accompanying radio- or chemotherapy, bone marrow transplantation, or infections. Compounds in the invention or pharmaceutical compositions employing these compounds may be useful in the treatment of cancer, AIDS, aplastic anemia, myelodysplastic syndrome, and infectious diseases, and in the enhancement of immune response.
    Type: Grant
    Filed: May 12, 1993
    Date of Patent: May 17, 1994
    Assignee: American Cyanamid Company
    Inventors: Semiramis Ayral-Kaloustian, Steven R. Schow, Mila T. Du, James J. Gibbons, Jr.
  • Method and apparatus for providing controlled light distribution from a cylindrical fiberoptic diffuser
    Patent number: 5303324
    Abstract: The invention discloses a cylindrical optical radiating device for obtaining controlled light distribution in a cylindrical pattern from an optical fiber. The device is constructed of a solid cylindrical tip made from material containing an optical scattering material in which a tapered central lumen having a conical shape has been drilled, cast or bored. Light emerging from the end of the fiber is radiated out in a cylindrical pattern through the use of the tapered central lumen.
    Type: Grant
    Filed: October 29, 1992
    Date of Patent: April 12, 1994
    Assignee: American Cyanamid Company
    Inventor: Scott Lundahl
  • Intermediates in the asymmetric synthesis of 3-substituted furanoside compounds
    Patent number: 5296620
    Abstract: Novel processes, intermediates and reagents for the preparation of 3-substituted furanose or furanoside compounds of Formula I: ##STR1## wherein M is hydrogen or alkyl (C.sub.1 -C.sub.3), A is halogen or A may be selected from a moiety of the formula: OR, SR, N.sub.3, SCR, OC--R or CN wherein R is hydrogen, branched or unbranched alkyl (C.sub.1 -C.sub.4) or phenyl which compounds have antiviral and other biological activity.
    Type: Grant
    Filed: March 12, 1993
    Date of Patent: March 22, 1994
    Assignee: American Cyanamid Company
    Inventor: Yuri E. Raifeld